gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5

1996 • 1,181 citations

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

1996 • 1,058 citations

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1996 • 971 citations

Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase γ

1997 • 671 citations

Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel

1993 • 600 citations

Activation of the cloned muscarinic potassium channel by G protein βγ subunits

1994 • 472 citations

Activation of Dual T Cell Signaling Pathways by the Chemokine RANTES

1995 • 463 citations

Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors

1997 • 454 citations

A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation

1997 • 420 citations

Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5

1997 • 394 citations

Evidence for Cell-Surface Association Between Fusin and the CD4-gp120 Complex in Human Cell Lines

1996 • 367 citations

Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor

1997 • 357 citations

Atrial G protein-activated K+ channel: expression cloning and molecular properties.

1993 • 355 citations

CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons

1997 • 327 citations

Chemokines and HIV–1 second receptors

1996 • 304 citations

Regulation of Human Chemokine Receptors CXCR4

1997 • 290 citations

Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor

1997 • 207 citations

HIV-1 Entry and Macrophage Inflammatory Protein-1β-mediated Signaling Are Independent Functions of the Chemokine Receptor CCR5

1997 • 183 citations

Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

1997 • 176 citations

Platelet-derived Growth Factor and Fibronectin-stimulated Migration Are Differentially Regulated by the Rac and Extracellular Signal-regulated Kinase Pathways

1997 • 173 citations

Differences in CD4 dependence for infectivity of laboratory-adapted and primary patient isolates of human immunodeficiency virus type 1

1994 • 148 citations

Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors

1996 • 139 citations

Direct G Protein Activation of Ion Channels?

1994 • 127 citations

Ligand-induced Desensitization of the Human CXC Chemokine Receptor-2 Is Modulated by Multiple Serine Residues in the Carboxyl-terminal Domain of the Receptor

1997 • 119 citations

Inhibition of an inwardly rectifying K+ channel by G-protein α-subunits

1996 • 116 citations

Metabotropic Glutamate Receptors Activate G-Protein-Coupled Inwardly Rectifying Potassium Channels inXenopusOocytes

1996 • 112 citations

CD4-Independent Binding of SIV gp120 to Rhesus CCR5

1997 • 109 citations

Agonist-induced Desensitization of the Mu Opioid Receptor-coupled Potassium Channel (GIRK1)

1995 • 102 citations

A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes.

1995 • 102 citations

Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses

1997 • 83 citations

Binding of Human Immunodeficiency Virus Type 1 to CD4 Induces Association of Lck and Raf-1 and Activates Raf-1 by a Ras-Independent Pathway

1996 • 83 citations

Receptor-mediated Endocytosis of CC-chemokines

1997 • 80 citations

Role of the C Terminus of the Interleukin 8 Receptor in Signal Transduction and Internalization

1996 • 69 citations

Binding of HIV-1 to Its Receptor Induces Tyrosine Phosphorylation of Several CD4-Associated Proteins, Including the Phosphatidylinositol 3-Kinase

1997 • 51 citations

The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and particpates in the activation of NF-kappa B

1996 • 45 citations

Intrinsic gating properties of a cloned G protein-activated inward rectifier K+ channel.

1995 • 35 citations

Deleted Work

1955 • 0 citations