Agonist-induced Desensitization of the Mu Opioid Receptor-coupled Potassium Channel (GIRK1)

Ionic channels of excitable membranes

1985 • 7,199 citations

Ionic Channels of Excitable Membranes

1985 • 3,014 citations

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

1993 • 935 citations

Molecular cloning and functional expression of a mu opioid receptor from rat brain

1994 • 805 citations

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

1987 • 616 citations

Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel

1993 • 600 citations

Drug addiction: A model for the molecular basis of neural plasticity

1993 • 548 citations

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

1983 • 471 citations

Direct Activation of Mammalian Atrial Muscarinic Potassium Channels by GTP Regulatory Protein G _k

1987 • 441 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

Ionic Channels and Their Regulation by G Protein Subunits

1990 • 413 citations

Molecular biology of opioid receptors

1993 • 358 citations

Atrial G protein-activated K+ channel: expression cloning and molecular properties.

1993 • 355 citations

The α Subunit of the GTP Binding Protein G _k Opens Atrial Potassium Channels

1987 • 317 citations

Drug receptors and the inhibition of nerve cells

1989 • 308 citations

The G protein-gated atrial K+ channel is stimulated by three distinct GIα-subunits

1988 • 306 citations

The Opiate Receptor

1974 • 188 citations

Mechanisms of cellular adaptive sensitivity changes: applications to opioid tolerance and dependence.

1989 • 176 citations

Differential regulation by cAMP-dependent protein kinase and protein kinase C of the mu opioid receptor coupling to a G protein-activated K+ channel.

1994 • 163 citations

Opioids activate both an inward rectifier and a novel voltage-gated potassium conductance in the hippocampal formation

1991 • 145 citations

Anomalous permeabilities of the egg cell membrane of a starfish in K+-Tl+ mixtures.

1977 • 112 citations

Transient homologous mu-opioid receptor desensitization in rat locus coeruleus neurons

1991 • 106 citations

Single potassium channels opened by opioids in rat locus ceruleus neurons.

1989 • 103 citations

Short-term desensitization of muscarinic K+ channel current in isolated atrial myocytes and possible role of GTP-binding proteins

1987 • 100 citations

Ca2+ extrusion across plasma membrane and Ca2+ uptake by intracellular stores

1991 • 99 citations

Chapter 12: Muscarinic acetylcholine receptor subtypes: localization and structure/function

1993 • 93 citations

Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes.

1993 • 85 citations

G protein activation of cardiac muscarinic K+ channels

1992 • 85 citations

Desensitization of the acetylcholine‐induced increase of potassium conductance in rabbit cardiac Purkinje fibres.

1986 • 69 citations

Activation of atrial muscarinic K+ channels by low concentrations ofβγ subunits of rat brain G protein

1989 • 68 citations

Fourier transform infrared difference spectroscopy of the nicotinic acetylcholine receptor: evidence for specific protein structural changes upon desensitization

1993 • 61 citations

Muscarinic K+ Channels Are Activated by βγ Subunits and Inhibited by the GDP-Bound Form of α Subunit of Transducin

1994 • 39 citations

Dual effects of K ions upon the inactivation of the anomalous rectifier of the tunicate egg cell membrane

1980 • 26 citations