A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation

Goodman and Gilman's the Pharmacological Basis of Therapeutics

1986 • 6,964 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Crystal Structure of the Aequorea victoria Green Fluorescent Protein

1996 • 2,167 citations

Primary structure of the Aequorea victoria green-fluorescent protein

1992 • 2,135 citations

Goodman and Gilman's The Pharmacological Basis of Therapeutics

1991 • 958 citations

Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

1996 • 938 citations

Sequence Alignment of the G-Protein Coupled Receptor Superfamily

1992 • 847 citations

Generation and analysis of 280,000 human expressed sequence tags.

1996 • 474 citations

A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration.

1994 • 361 citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

1996 • 332 citations

From DNA sequence to biological function

1996 • 309 citations

Visual arrestin interaction with rhodopsin. Sequential multisite binding ensures strict selectivity toward light-activated phosphorylated rhodopsin

1993 • 303 citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

1996 • 264 citations

Synergistic Regulation of β₂-Adrenergic Receptor Sequestration: Intracellular Complement of β-Adrenergic Receptor Kinase and β-Arrestin Determine Kinetics of Internalization

1997 • 231 citations

Construction of mutant and chimeric genes using the polymerase chain reaction

1989 • 224 citations

Internal Trafficking and Surface Mobility of a Functionally Intact β₂-Adrenergic Receptor-Green Fluorescent Protein Conjugate

1997 • 220 citations

Role of Phosphorylation in Agonist-promoted β2-Adrenergic Receptor Sequestration

1995 • 213 citations

Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimeras.

1995 • 195 citations

Visual Arrestin Binding to Rhodopsin

1995 • 157 citations

The Conserved Seven-Transmembrane Sequence NP(X)2,3Y of the G-Protein-Coupled Receptor Superfamily Regulates Multiple Properties of the .beta.2-Adrenergic Receptor

1995 • 151 citations

Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2.

1994 • 150 citations

Visualization of protein transport along the secretory pathway using green fluorescent protein

1995 • 131 citations

Regulation of G Protein-Coupled Receptors by Receptor Kinases and Arrestins

1995 • 128 citations

Adrenergic receptors. Models for regulation of signal transduction processes.

1990 • 96 citations

Binding of wild type and chimeric arrestins to the m2 muscarinic cholinergic receptor

1993 • 96 citations

Members of the G Protein-Coupled Receptor Kinase Family That Phosphorylate the β₂-Adrenergic Receptor Facilitate Sequestration

1996 • 88 citations

The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and Expressed Sequence Tag Databases

1997 • 86 citations

Selective amplification of protein-coding regions of large sets of genes using statistically designed primer sets

1996 • 37 citations