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The Fate of dsRNA in the Nucleus

Data up to Jan 2025

Published2001
Citations470
References64

Total Citations Per Year

Abstract

References (64)

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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Conserved Structures and Diversity of Functions of RNA-Binding Proteins

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RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

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RNA interference—2001

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TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus

1998 • 557 citations

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Double-Stranded RNA as a Template for Gene Silencing

2000 • 421 citations

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Cloning and characterization of PSF, a novel pre-mRNA splicing factor.

1993 • 359 citations

Quality Control of mRNA Function

2001 • 326 citations

A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs.

1989 • 318 citations

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1998 • 314 citations

Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase.

1994 • 297 citations

hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing

1999 • 253 citations

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway

1997 • 236 citations

The Role of RNA Editing in Controlling Glutamate Receptor Channel Properties

1996 • 230 citations

TAP (NXF1) Belongs to a Multigene Family of Putative RNA Export Factors with a Conserved Modular Architecture

2000 • 224 citations

A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction.

1994 • 217 citations

Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcripts

1997 • 196 citations

RNA editing and hypermutation by adenosine deamination

1997 • 186 citations

PSF Is a Novel Corepressor That Mediates Its Effect through Sin3A and the DNA Binding Domain of Nuclear Hormone Receptors

2001 • 172 citations

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export

1997 • 171 citations

Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF andDrosophilaNONA/BJ6

1993 • 163 citations

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

1996 • 155 citations

Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain

1991 • 147 citations

The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis

1991 • 146 citations

Overexpression of TAP/p15 Heterodimers Bypasses Nuclear Retention and Stimulates Nuclear mRNA Export

2001 • 135 citations

NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss.

1993 • 115 citations

The RNA-splicing Factor PSF/p54 Controls DNA-Topoisomerase I Activity by a Direct Interaction

1998 • 94 citations

Identification and Characterization of RNA Editing Events within the 5‐HT2C Receptora

1998 • 89 citations

Intron sequence directs RNA editing of the glutamate receptor subunit GluR2 coding sequence.

1994 • 87 citations

The Intracisternal A-Particle Proximal Enhancer-Binding Protein Activates Transcription and Is Identical to the RNA- and DNA-Binding Protein p54nrb/NonO

1997 • 82 citations

Polypyrimidine Tract-Binding Protein-Associated Splicing Factor Is a Negative Regulator of Transcriptional Activity of the Porcine P450scc Insulin-Like Growth Factor Response Element

2000 • 74 citations

Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion

2000 • 72 citations

Myotonic Dystrophy

2000 • 70 citations

Electron Tomography Reveals Posttranscriptional Binding of Pre-Mrnps to Specific Fibers in the Nucleoplasm

2000 • 63 citations

Molecular analysis of no-on-transient A, a gene required for normal vision in drosophila

1990 • 61 citations

NonO enhances the association of many DNA-binding proteins to their targets

1997 • 60 citations

Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells

1993 • 59 citations

Identification of tyrosine‐phosphorylated proteins associated with the nuclear envelope

2001 • 57 citations

Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB

2000 • 55 citations

The cytoplasm of Xenopus oocytes contains a factor that protects double-stranded RNA from adenosine-to-inosine modification.

1994 • 51 citations

Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle

1999 • 50 citations

The snRNP-free U1A (SF-A) complex(es): Identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor

1998 • 45 citations

PSF/p54nrb Stimulates “Jumping” of DNA Topoisomerase I between Separate DNA Helices

2000 • 44 citations

Mason–Pfizer Monkey Virus (MPMV) Constitutive Transport Element (CTE) Functions in a Position-Dependent Manner

1997 • 39 citations

Transcription Modulation by a Rat Nuclear Scaffold Protein, P130, and a Rat Highly Repetitive DNA Component or Various Types of Animal and Plant Matrix or Scaffold Attachment Regions

2000 • 38 citations

Nuclear NonO/p54nrb Protein Is a Nonclassical Carbonic Anhydrase

2000 • 34 citations

A Mammalian Activity Required for the Second Step of Pre-messenger RNA Splicing

1995 • 29 citations

Loss of Expression of a 55 kDa Nuclear Protein (nmt55) in Estrogen Receptor-Negative Human Breast Cancer

1997 • 25 citations

Purification and characterization of nuclear scaffold proteins which bind to a highly repetitive bent DNA from rat liver

1993 • 25 citations

Modulation of Double‐Stranded RNAs in Vivo by RNA Duplex Unwindasea

1992 • 20 citations

Properties of a DNA-Binding Protein from Rat Nuclear Scaffold Fraction

1993 • 17 citations

Involvement of phosphorylation in binding of nuclear scaffold proteins from rat liver to a highly repetitive DNA component

1998 • 16 citations

The RRM Protein NonA from Drosophila Forms a Complex with the RRM Proteins Hrb87F and S5 and the Zn Finger Protein PEP on hnRNA

1999 • 15 citations

Nuclear antisense RNA

1994 • 12 citations

The puff-specific RRM protein NonA is a single-stranded nucleic acid binding protein

1999 • 10 citations

Deleted Work

1955 • 0 citations

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