Overexpression of TAP/p15 Heterodimers Bypasses Nuclear Retention and Stimulates Nuclear mRNA Export

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

The leucine-rich repeat: a versatile binding motif

1994 • 1,209 citations

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

2000 • 923 citations

Kinetic analysis of translocation through nuclear pore complexes

2001 • 756 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus

1998 • 557 citations

The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

2000 • 514 citations

Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores

1997 • 510 citations

The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human

1999 • 431 citations

Splicing is required for rapid and efficient mRNA export in metazoans

1999 • 375 citations

REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export

2000 • 365 citations

Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export

2000 • 351 citations

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon–exon junctions

2000 • 337 citations

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates

2000 • 329 citations

Pre-mRNA Splicing Imprints mRNA in the Nucleus with a Novel RNA-Binding Protein that Persists in the Cytoplasm

2000 • 326 citations

Release of Proteins and Peptides from Fusion Proteins Using a Recombinant Plant Virus Proteinase

1994 • 282 citations

Nuclear mRNA Export Requires Complex Formation between Mex67p and Mtr2p at the Nuclear Pores

1998 • 263 citations

REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus

2001 • 248 citations

The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences

1999 • 246 citations

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway

1997 • 236 citations

Binding of the Mex67p/Mtr2p Heterodimer to Fxfg, Glfg, and Fg Repeat Nucleoporins Is Essential for Nuclear mRNA Export

2000 • 229 citations

TAP (NXF1) Belongs to a Multigene Family of Putative RNA Export Factors with a Conserved Modular Architecture

2000 • 224 citations

TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus

1999 • 179 citations

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export

1997 • 171 citations

The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain

2000 • 146 citations

The Acute Myeloid Leukemia-Associated Protein, Dek, Forms a Splicing-Dependent Interaction with Exon-Product Complexes

2000 • 126 citations

Identification of Novel Import and Export Signals of Human TAP, the Protein That Binds to the Constitutive Transport Element of the Type D Retrovirus mRNAs

1999 • 125 citations

Retroviruses as Model Systems for the Study of Nuclear RNA Export Pathways

1998 • 123 citations

Minimal Rev-response element for type 1 human immunodeficiency virus

1991 • 117 citations

NXT1 (p15) Is a Crucial Cellular Cofactor in TAP-Dependent Export of Intron-Containing RNA in Mammalian Cells

2001 • 106 citations

The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p

2000 • 106 citations

Identification of an NTF2-Related Factor That Binds Ran-GTP and Regulates Nuclear Protein Export

1999 • 91 citations

Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins

2000 • 87 citations

Posttranscriptional regulation by the human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex proteins through a heterologous RNA binding site

1992 • 79 citations

Nxt1 Is Necessary for the Terminal Step of Crm1-Mediated Nuclear Export

2001 • 71 citations

In vitro splicing of the terminal intervening sequence of Saccharomyces cerevisiae cytochrome b pre-mRNA.

1987 • 55 citations

Roles of U4 and U6 snRNAs in the assembly of splicing complexes.

1992 • 52 citations

RanGTP-Binding Protein NXT1 Facilitates Nuclear Export of Different Classes of RNA In Vitro

2000 • 44 citations

Analysis of Cellular Factors That Mediate Nuclear Export of RNAs Bearing the Mason-Pfizer Monkey Virus Constitutive Transport Element

2000 • 40 citations