Regulation of serotonin-2C receptor G-protein coupling by RNA editing

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1991 • 1,465 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

Control of Kinetic Properties of AMPA Receptor Channels by Nuclear RNA Editing

1994 • 735 citations

Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor

1988 • 691 citations

RNA editing of AMPA receptor subunit GluR-B: A base-paired intron-exon structure determines position and efficiency

1993 • 657 citations

A mammalian RNA editing enzyme

1996 • 512 citations

Determinants of ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: Diversity by RNA editing

1993 • 453 citations

[20] Computer prediction of RNA structure

1989 • 387 citations

RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase

1996 • 336 citations

Ca2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6.

1993 • 304 citations

Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase

1995 • 260 citations

Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands.

1994 • 249 citations

Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling.

1993 • 226 citations

Structural Requirements for RNA Editing in Glutamate Receptor Pre-mRNAs by Recombinant Double-stranded RNA Adenosine Deaminase

1996 • 157 citations

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

1996 • 155 citations

The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins

1996 • 155 citations

Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine

1995 • 145 citations

Glutamate Receptor RNA Editing in Vitro by Enzymatic Conversion of Adenosine to Inosine

1995 • 141 citations

Reciprocal binding properties of 5-hydroxytryptamine type 2C receptor agonists and inverse agonists.

1994 • 88 citations

Intron sequence directs RNA editing of the glutamate receptor subunit GluR2 coding sequence.

1994 • 87 citations

The mouse 5-HT1C receptor contains eight hydrophobic domains and is X-linked

1991 • 70 citations

Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization.

1995 • 70 citations

Molecular pharmacological differences in the interaction of serotonin with 5-hydroxytryptamine1C and 5-hydroxytryptamine2 receptors.

1992 • 64 citations

G Protein GTPase-Activating Proteins: Regulation of Speed, Amplitude, and Signaling Selectivity

1995 • 43 citations

Receptor reserve for D2 dopaminergic inhibition of prolactin release in vivo and in vitro.

1991 • 30 citations