Arteriosclerosis, vascular calcifications and cardiovascular disease in uremia

Quantification of coronary artery calcium using ultrafast computed tomography

1990 • 7,166 citations

Clinical epidemiology of cardiovascular disease in chronic renal disease

1998 • 3,896 citations

Aortic Stiffness Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Hypertensive Patients

2001 • 3,767 citations

Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis

2004 • 2,590 citations

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1998 • 2,473 citations

Coronary-Artery Calcification in Young Adults with End-Stage Renal Disease Who Are Undergoing Dialysis

2000 • 2,426 citations

CORONARY-ARTERY CALCIFICATION IN YOUNG ADULTS WITH END-STAGE RENAL DISEASE WHO ARE UNDERGOING DIALYSIS

2000 • 2,241 citations

Impact of Aortic Stiffness on Survival in End-Stage Renal Disease

1999 • 2,131 citations

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

1997 • 2,050 citations

Accelerated Atherosclerosis in Prolonged Maintenance Hemodialysis

1974 • 1,789 citations

Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality

2003 • 1,778 citations

Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients

2002 • 1,452 citations

Arterial Calcifications, Arterial Stiffness, and Cardiovascular Risk in End-Stage Renal Disease

2001 • 1,391 citations

Phosphate Regulation of Vascular Smooth Muscle Cell Calcification

2000 • 1,361 citations

Association of Elevated Serum PO4, Ca × PO4 Product, and Parathyroid Hormone with Cardiac Mortality Risk in Chronic Hemodialysis Patients

2001 • 1,198 citations

The Effects of Parathyroid Hormone and Alendronate Alone or in Combination in Postmenopausal Osteoporosis

2003 • 1,150 citations

Cardiac calcification in adult hemodialysis patients

2002 • 1,084 citations

Coronary Artery Calcification: Pathophysiology, Epidemiology, Imaging Methods, and Clinical Implications

1996 • 1,066 citations

Bone morphogenetic protein expression in human atherosclerotic lesions.

1993 • 1,014 citations

Arterial Calcification and Not Lumen Stenosis Is Highly Correlated With Atherosclerotic Plaque Burden in Humans: A Histologic Study of 723 Coronary Artery Segments Using Nondecalcifying Methodology

1998 • 997 citations

Arterial stiffening and vascular calcifications in end‐stage renal disease

2000 • 991 citations

Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study

2003 • 902 citations

The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification

2003 • 888 citations

Human Vascular Smooth Muscle Cells Undergo Vesicle-Mediated Calcification in Response to Changes in Extracellular Calcium and Phosphate Concentrations

2004 • 887 citations

Arterial Wave Reflections and Survival in End-Stage Renal Failure

2001 • 851 citations

The Effects of Parathyroid Hormone, Alendronate, or Both in Men with Osteoporosis

2003 • 831 citations

Electron beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients

1996 • 794 citations

Smooth Muscle Cell Phenotypic Transition Associated With Calcification

2001 • 789 citations

Advanced Coronary and Carotid Arteriopathy in Young Adults With Childhood-Onset Chronic Renal Failure

2002 • 719 citations

Medial Localization of Mineralization-Regulating Proteins in Association With Mönckeberg’s Sclerosis

1999 • 626 citations

Abdominal Aortic Calcific Deposits Are an Important Predictor of Vascular Morbidity and Mortality

2001 • 620 citations

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

1994 • 616 citations

Lipid Oxidation Products Have Opposite Effects on Calcifying Vascular Cell and Bone Cell Differentiation

1997 • 602 citations

Traditional Cardiovascular Disease Risk Factors in Dialysis Patients Compared with the General Population

2002 • 592 citations

Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification

2003 • 578 citations

Arterial Calcifications and Bone Histomorphometry in End-Stage Renal Disease

2004 • 578 citations

Vascular Calcification Mechanisms

2004 • 560 citations

Tumor Necrosis Factor-α Promotes In Vitro Calcification of Vascular Cells via the cAMP Pathway

2000 • 512 citations

Pathophysiology of Vascular Calcification in Chronic Kidney Disease

2004 • 482 citations

Bone loss and the progression of abdominal aortic calcification over a 25 year period: The Framingham heart study

2001 • 475 citations

Cardiac and arterial interactions in end-stage renal disease

1996 • 473 citations

Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins

2002 • 451 citations

Diabetes Mellitus, Aortic Stiffness, and Cardiovascular Mortality in End-Stage Renal Disease

2001 • 447 citations

Calcification of Vascular Smooth Muscle Cell Cultures

1999 • 446 citations

Prognostic value of coronary calcification and angiographic stenoses in patients undergoing coronary angiography

1996 • 443 citations

Osteopontin Inhibits Mineral Deposition and Promotes Regression of Ectopic Calcification

2002 • 407 citations

Progression of Aortic Valve Calcification

2001 • 397 citations

RANK Ligand and Osteoprotegerin

2002 • 396 citations

Cardiac Valve Calcification as an Important Predictor for All-Cause Mortality and Cardiovascular Mortality in Long-Term Peritoneal Dialysis Patients

2003 • 394 citations

Long-Term Prognostic Value of Coronary Calcification Detected by Electron-Beam Computed Tomography in Patients Undergoing Coronary Angiography

2001 • 389 citations

Osteoprotegerin Inhibits Artery Calcification Induced by Warfarin and by Vitamin D

2001 • 381 citations

Progression of Aortic Calcification Is Associated With Metacarpal Bone Loss During Menopause

2000 • 379 citations

The Serum Protein α2-HS Glycoprotein/Fetuin Inhibits Apatite Formation in Vitro and in Mineralizing Calvaria Cells

1996 • 355 citations

Risk factors and mortality associated with calciphylaxis in end-stage renal disease

2001 • 348 citations

Atherosclerosis and arteriosclerosis in chronic renal failure

1997 • 345 citations

Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro

2004 • 333 citations

Monocyte/Macrophage Regulation of Vascular Calcification In Vitro

2002 • 330 citations

Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells

2002 • 326 citations

Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels

2003 • 317 citations

Inactivation of the Osteopontin Gene Enhances Vascular Calcification of Matrix Gla Protein–deficient Mice

2002 • 316 citations

Phosphate-Induced Vascular Calcification

2004 • 300 citations

1,25-Dihydroxyvitamin D ₃ Increases In Vitro Vascular Calcification by Modulating Secretion of Endogenous Parathyroid Hormone–Related Peptide

1998 • 294 citations

Signal Transduction of Mechanical Stresses in the Vascular Wall

1998 • 293 citations

Vascular Calcification

2003 • 285 citations

Calcification of Human Vascular Cells In Vitro Is Correlated With High Levels of Matrix Gla Protein and Low Levels of Osteopontin Expression

1998 • 264 citations

Excessive mineralization with growth plate closure in rats on chronic warfarin treatment.

1982 • 261 citations

Poly[allylamine hydrochloride] (RenaGel): A noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure

1997 • 250 citations

Pathophysiological mechanisms of vascular calcification in end-stage renal disease

2001 • 248 citations

Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells

2001 • 226 citations

BMP-7 Is an Efficacious Treatment of Vascular Calcification in a Murine Model of Atherosclerosis and Chronic Renal Failure

2003 • 217 citations

Cardiovascular Calcifications in Uremic Patients

2003 • 213 citations

High-Density Lipoprotein Regulates Calcification of Vascular Cells

2002 • 206 citations

Prevalence and Clinical Correlates of Coronary Artery Disease among New Dialysis Patients in the United States

2001 • 203 citations

Association of Inflammation and Malnutrition with Cardiac Valve Calcification in Continuous Ambulatory Peritoneal Dialysis Patients

2001 • 199 citations

Role of Calcium-Phosphate Product and Bone-Associated Proteins on Vascular Calcification in Renal Failure

2001 • 186 citations

C-Reactive Protein Is Associated With Subclinical Epicardial Coronary Calcification in Men and Women

2002 • 178 citations

Coronary artery calcification and aortic pulse wave velocity in chronic kidney disease patients

2004 • 177 citations

Teriparatide (Human Parathyroid Hormone (1–34)) Inhibits Osteogenic Vascular Calcification in Diabetic Low Density Lipoprotein Receptor-deficient Mice

2003 • 175 citations

Parathyroid Hormone–Related Peptide as a Local Regulator of Vascular Calcification

1997 • 173 citations

Medial Artery Calcification Predicts Cardiovascular Mortality in Patients With NIDDM

1994 • 166 citations

The Role of Gla Proteins in Vascular Calcification

1998 • 165 citations

Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats

2003 • 165 citations

Significant association between the progression of coronary artery calcification and dyslipidemia in patients on chronic hemodialysis

2001 • 148 citations

Coronary artery calcification measured with electron-beam computerized tomography correlates poorly with coronary artery angiography in dialysis patients

2004 • 134 citations

Heritability of Coronary Artery Calcium Quantity Measured by Electron Beam Computed Tomography in Asymptomatic Adults

2002 • 132 citations

Racial Differences in Coronary Artery Calcification in Older Adults

2002 • 131 citations

Valvular calcification in hemodialysis patients randomized to calcium-based phosphorus binders or sevelamer.

2004 • 115 citations

The Effects of Sevelamer and Calcium Acetate on Proxies of Atherosclerotic and Arteriosclerotic Vascular Disease in Hemodialysis Patients

2003 • 107 citations

Matrix Gla protein synthesis and gamma-carboxylation in the aortic vessel wall and proliferating vascular smooth muscle cells--a cell system which resembles the system in bone cells.

1999 • 97 citations

Autosomal Genome-Wide Scan for Coronary Artery Calcification Loci in Sibships at High Risk for Hypertension

2002 • 91 citations

Evaluation of the Aortic Root by MRI

1998 • 90 citations

Cardiac calcification in renal patients: what we do and don't know

2004 • 83 citations

Serum concentration of calcium, 1,25 vitamin D and parathyroid hormone are not correlated with coronary calcifications. An electron beam computed tomography study

1998 • 77 citations

Cyclic strain inhibits switching of smooth muscle cells to an osteoblast‐like phenotype

2003 • 71 citations

Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease

2004 • 70 citations

Matrix Gla Protein Synthesis and Gamma-carboxylation in the Aortic Vessel Wall and Proliferating Vascular Smooth Muscle Cells

1999 • 56 citations

Hypoparathyroidism Potentiates Cardiovascular Complications through Disturbed Calcium Metabolism: Possible Risk of Vitamin D<sub>3</sub> Analog Administration in Dialysis Patients with End-Stage Renal Disease

2000 • 48 citations

Prevalence and progression of peripheral arterial calcifications in patients with ESRD

2002 • 46 citations

Isolation of calcifiable vesicles from aortas of rabbits fed with high cholesterol diets

2000 • 40 citations

Bone mineral density may be related to atherosclerosis in hemodialysis patients

2003 • 19 citations