Atherosclerosis and arteriosclerosis in chronic renal failure

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

The Effect of Vitamin E and Beta Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers

1994 • 4,626 citations

Wine, alcohol, platelets, and the French paradox for coronary heart disease

1992 • 3,600 citations

Compensatory Enlargement of Human Atherosclerotic Coronary Arteries

1987 • 3,549 citations

Lack of Effect of Long-Term Supplementation with Beta Carotene on the Incidence of Malignant Neoplasms and Cardiovascular Disease

1996 • 2,429 citations

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1996 • 2,163 citations

Vitamin E Consumption and the Risk of Coronary Disease in Women

1993 • 2,158 citations

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

1992 • 2,138 citations

Advanced oxidation protein products as a novel marker of oxidative stress in uremia

1996 • 1,856 citations

Accelerated Atherosclerosis in Prolonged Maintenance Hemodialysis

1974 • 1,789 citations

Hyperinsulinemia as an Independent Risk Factor for Ischemic Heart Disease

1996 • 1,727 citations

Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine

1993 • 1,665 citations

Physiologic basis for assessing critical coronary stenosis

1974 • 1,503 citations

The oxidation hypothesis of atherosclerosis

1994 • 1,418 citations

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

1992 • 1,332 citations

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

1995 • 1,244 citations

Acute Vascular Endothelial Changes Associated with Increased Blood Velocity Gradients

1968 • 1,237 citations

Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells

1985 • 1,237 citations

Reductions in Arterial Diameter Produced by Chronic Decreases in Blood Flow Are Endothelium-Dependent

1986 • 1,106 citations

Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries.

1988 • 1,024 citations

Aortic input impedance in normal man: relationship to pressure wave forms.

1980 • 1,009 citations

Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits?

1996 • 1,007 citations

Haemodynamic shear stress activates a K+ current in vascular endothelial cells

1988 • 1,003 citations

Dietary Antioxidant Vitamins and Death from Coronary Heart Disease in Postmenopausal Women

1996 • 976 citations

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

1995 • 886 citations

Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.

1996 • 884 citations

Adaptive regulation of wall shear stress to flow change in the canine carotid artery

1980 • 812 citations

The impact of anemia on cardiomyopathy, morbidity, and mortality in end-stage renal disease

1996 • 758 citations

Epidemiology as a Guide to Clinical Decisions

1980 • 708 citations

Mechanical stress mechanisms and the cell. An endothelial paradigm.

1993 • 636 citations

Relation of pulse pressure and blood pressure reduction to the incidence of myocardial infarction.

1994 • 604 citations

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

1996 • 587 citations

Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.

1996 • 557 citations

Pulsatile versus steady component of blood pressure: a cross-sectional analysis and a prospective analysis on cardiovascular mortality.

1989 • 536 citations

Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women

1994 • 534 citations

Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator.

1991 • 529 citations

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

1996 • 521 citations

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

1994 • 498 citations

A Survey of Vascular Access for Haemodialysis in The Netherlands

1991 • 474 citations

Cardiac and arterial interactions in end-stage renal disease

1996 • 473 citations

Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency.

1994 • 473 citations

The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.

1987 • 465 citations

Association between Prior Cytomegalovirus Infection and the Risk of Restenosis after Coronary Atherectomy

1996 • 446 citations

Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis.

1996 • 428 citations

Comparison of Simultaneously Recorded Central and Peripheral Arterial Pressure Pulses During Rest, Exercise and Tilted Position in Man

1955 • 419 citations

Mechanical Principles in Arterial Disease

1995 • 394 citations

Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells

1990 • 392 citations

Aortic and large artery compliance in end-stage renal failure

1990 • 381 citations

Parallel cardiac and vascular adaptation in hypertension.

1992 • 374 citations

Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty.

1995 • 363 citations

Apo(a) isoforms predict risk for coronary heart disease. A study in six populations.

1992 • 358 citations

McDonald's Blood Flow in Arteries : Theoretic, Experimental and Clinical Principles

1990 • 354 citations

The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium.

1996 • 344 citations

Effects of Thiazide Diuretics on Plasma Lipids and Lipoproteins in Mildly Hypertensive Patients

1981 • 338 citations

Textbook of Hypertension

1995 • 337 citations

Triglyceride- and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin.

1994 • 332 citations

Cardiac hypertrophy, aortic compliance, peripheral resistance, and wave reflection in end-stage renal disease. Comparative effects of ACE inhibition and calcium channel blockade.

1994 • 331 citations

Outcome and risk factors of ischemic heart disease in chronic uremia

1996 • 327 citations

Mechanical factors predisposing to intimal hyperplasia and medial thickening in autogenous vein grafts.

1989 • 325 citations

Cohort Study of Cytomegalovirus Infection as a Risk Factor for Carotid Intimal-Medial Thickening, a Measure of Subclinical Atherosclerosis

1996 • 304 citations

High-resolution B-mode ultrasonography in evaluation of atherosclerosis in uremia

1995 • 303 citations

Glucose Intolerance in Uremia

1978 • 298 citations

Arterial calcification and pathology in uremic patients undergoing dialysis

1979 • 297 citations

Soft tissue calcification in pediatric patients with end-stage renal disease

1990 • 294 citations

PLASMA ENDOTHELIN LEVELS IN PATIENTS WITH URAEMIA

1989 • 292 citations

Lipoprotein(a) is an independent risk factor for cardiovascular disease in hemodialysis patients.

1992 • 290 citations

Patients With Early-Onset Peripheral Vascular Disease Have Increased Levels of Autoantibodies Against Oxidized LDL

1995 • 288 citations

Prediction of angiographic change in native human coronary arteries and aortocoronary bypass grafts. Lipid and nonlipid factors.

1990 • 284 citations

Coronary circulation in dogs with an experimental decrease in aortic compliance

1993 • 280 citations

Enhanced LDL oxidation in uremic patients: An additional mechanism for accelerated atherosclerosis?

1994 • 276 citations

Subendocardial ischemia after cardiopulmonary bypass

1972 • 265 citations

Increased systolic pressure in chronic uremia. Role of arterial wave reflections.

1992 • 258 citations

BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells.

1996 • 251 citations

Intermediate-density lipoprotein and cholesterol-rich very low density lipoprotein in angiographically determined coronary artery disease.

1981 • 248 citations

High dose B-vitamin treatment of hyperhomocysteinemia in dialysis patients

1996 • 242 citations

Pressure-induced myogenic activation of cat cerebral arteries is dependent on intact endothelium.

1987 • 229 citations

Elastic modulus of the radial artery wall material is not increased in patients with essential hypertension.

1994 • 228 citations

Evidence for high risk of cerebral hemorrhage in chronic dialysis patients

1993 • 221 citations

Ischemic heart disease in patients with uremia undergoing maintenance hemodialysis

1979 • 221 citations

Wave reflections and cardiac hypertrophy in chronic uremia. Influence of body size.

1993 • 218 citations

Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells.

1994 • 213 citations

Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells.

1996 • 207 citations

The role of hypertension in hemodialysis-associated atherosclerosis

1980 • 207 citations

Risk factors for the development of left ventricular hypertrophy in a prospectively followed cohort of dialysis patients.

1994 • 206 citations

Hemodialysis membrane-induced activation of phagocyte oxidative metabolism detected in vivo and in vitro within microamounts of whole blood

1985 • 204 citations

Remodeling of the Radial Artery in Response to a Chronic Increase in Shear Stress

1996 • 197 citations

ASSOCIATION BETWEEN PRIOR CYTOMEGALOVIRUS INFECTION AND THE RISK OF RESTENOSIS AFTER CORONARY ATHERECTOMY

1996 • 195 citations

Combined report on regular dialysis and transplantation in Europe, 3, 1972.

1973 • 188 citations

Common Carotid Artery Stiffness and Patterns of Left Ventricular Hypertrophy in Hypertensive Patients

1995 • 182 citations

Water soluble vitamins in chronic hemodialysis patients and need for supplementation

1993 • 181 citations

Lipid and Apolipoprotein Profiles of Uremic Dyslipoproteinemia -Relation to Renal Function and Dialysis

1991 • 180 citations

Possible Role of Cytomegalovirus in Atherogenesis

1990 • 177 citations

Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits.

1995 • 176 citations

Effect of chronic administration of propranolol on lipoprotein composition

1976 • 173 citations

Hyperhomocysteinemia and the risk for vascular disease in hemodialysis patients.

1995 • 173 citations

Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients

1995 • 162 citations

Effect of hemodialysis on lipid peroxidation and antioxidant system in patients with chronic renal failure

1992 • 161 citations

Hyperhomocysteinaemia: a significant risk factor for cardiovascular disease in renal transplant recipients

1994 • 151 citations

Relationship of coronary risk factors to hemodialysis-associated ischemic heart disease

1982 • 151 citations

Vascular changes in hemodialysis patients in response to recombinant human erythropoietin

1989 • 150 citations

Causes of death in dialysis patients

1994 • 150 citations

Regression of left ventricular hypertrophy in dialysis patients following correction of anemia with recombinant human erythropoietin.

1990 • 149 citations

Lipid-lowering therapy in patients with renal disease

1995 • 144 citations

Studies of the vessel wall properties in hemodialysis patients

1994 • 143 citations

Elevated plasma concentrations of lipoprotein(a) in patients with end-stage renal disease are not related to the size polymorphism of apolipoprotein(a).

1993 • 142 citations

Cardiovascular disease in uremic patients on hemodialysis.

1975 • 140 citations

Increased cardiovascular risk factors and features of endothelial activation and dysfunction in dialyzed uremic patients

1994 • 139 citations

Changes of Vascular Architecture Independent of Blood Pressure in Experimental Uremia

1995 • 137 citations

Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

1996 • 136 citations

Impairment of Endothelium-Dependent Dilation in Rabbit Renal Arteries by Oxidized Lipoprotein(a)

1995 • 136 citations

Transport of ¹⁴ C-4-Cholesterol between Serum and Wall in the Perfused Dog Common Carotid Artery

1973 • 128 citations

Comparative mortality from cardiovascular disease in patients with chrome renal failure

1994 • 125 citations

Lipid Peroxidation Abnormalities in Hemodialyzed Patients

1993 • 125 citations

Alcohol consumption, serum low density lipoprotein cholesterol concentration, and risk of ischaemic heart disease: six year follow up in the Copenhagen male study

1996 • 124 citations

Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status

1991 • 124 citations

Accelerated Atherosclerosis in Chronic-Dialysis Patients – Another Look

1978 • 122 citations

Pressure-induced connective tissue synthesis in pulmonary artery segments is dependent on intact endothelium.

1989 • 114 citations

Salt and water retention and calcium blockade in uremia.

1990 • 114 citations

ACCELERATED ATHEROSCLEROSIS IN LONG-TERM DIALYSIS AND RENAL-TRANSPLANT PATIENTS: FACT OR FICTION?

1980 • 110 citations

Cytokines and smooth muscle cells in atherosclerosis

1993 • 109 citations

Serum Lipids and Lipoproteins during Continuous Ambulatory Peritoneal Dialysis

1986 • 104 citations

Enhanced development of atherosclerosis in cholesterol-fed rabbits by suppression of cell-mediated immunity.

1995 • 103 citations

Analysis of cardiovascular risk factors in chronic hemodialysis patients with special attention to the hyperlipoproteinemias

1983 • 101 citations

Apolipoprotein(a) phenotypes predict the risk for carotid atherosclerosis in patients with end-stage renal disease.

1994 • 100 citations

The role of mechanical and humoral factors in growth regulation of vascular smooth muscle and cardiac myocytes

1993 • 98 citations

Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a).

1995 • 96 citations

Resistance to erythropoietin in iron-overloaded haemodialysis patients can be overcome by ascorbic acid administration

1995 • 94 citations

Plasma cholesterol metabolism in end-stage renal disease. Difference between treatment by hemodialysis or peritoneal dialysis.

1986 • 92 citations

Effect of alpha-tocopherol on restenosis after angioplasty in a model of experimental atherosclerosis.

1995 • 90 citations

Carbamylation-induced alterations in low-density lipoprotein metabolism

1992 • 88 citations

Endothelin in Renal Failure

1990 • 88 citations

d‐α‐Tocopherol inhibits low density lipoprotein induced proliferation and protein kinase C activity in vascular smooth muscle cells

1993 • 84 citations

Is intimal hyperplasia an adaptive response or a pathologic process?—observations on the nature of nonatherosclerotic intimal thickening

1989 • 76 citations

Reduced, Free and Total Fractions of Homocysteine and Other Thiol Compounds in Plasma from Patients with Renal Failure

1995 • 76 citations

Stimulation of endothelial secretion of tissue-type plasminogen activator by repetitive stretch

1991 • 72 citations

Lipoprotein Metabolism in Patients with Chronic Uremia

1978 • 71 citations

Atherosclerosis and lipid disorders after renal transplantation.

1991 • 71 citations

Cardiovascular Disease in Dialysis Patients

1974 • 69 citations

Altered platelet and vascular prostaglandin-generation in patients with renal failure and prolonged bleeding times

1978 • 69 citations

Increased plasma homocysteine concentration in patients with chronic renal failure.

1992 • 65 citations

Atherogenesis and cardiac death: are they related to dialysis procedure and biocompatibility?

1994 • 63 citations

High serum lipoprotein(a) concentrations in uremic patients treated with continuous ambulatory peritoneal dialysis.

1992 • 61 citations

Lipoprotein Abnormalities in Chronic Haemodialysis Patients

1988 • 60 citations

Enhanced production of nitric oxide by blood-dialysis membrane interaction.

1995 • 60 citations

Pharmacological treatment of hypertension

1994 • 56 citations

Hypertension Promotes Coronary Calcium Deposit in Asymptomatic Men

1996 • 56 citations

Vascular endothelial cell function and cardiovascular risk factors in patients with chronic renal failure.

1995 • 55 citations

Protection from atherosclerosis in vein grafts by a rigid external support.

1993 • 55 citations

Plasma lipoproteins and lecithin:cholesterol acyltransferase distribution in patients on dialysis

1984 • 55 citations

Reduced lipid concentrations during four years of dialysis with low molecular weight heparin

1991 • 52 citations

Plasma level of lipoprotein Lp(a) is high in predialysis or hemodialysis, but not in CAPD

1992 • 51 citations

Beta-Amyloid Deposition in the Medial Temporal Lobe in Elderly Non-Demented Brains and in Alzheimer’s Disease

1995 • 50 citations

Enhanced scavenger receptor expression in monocyte-macrophages in dialysis patients

1996 • 47 citations

Receptors for advanced glycation end-products (AGE)--expression by endothelial cells in non-diabetic uraemic patients

1996 • 45 citations

Serum vitamin A levels and associated abnormalities in patients on regular dialysis treatment.

1979 • 45 citations

Cardiovascular function in hemodialysis patients.

1991 • 44 citations

Relation between carotid artery atherosclerosis and time on dialysis. A non-invasive study in vivo.

1994 • 44 citations

Serum Ascorbic Acid in Patients Undergoing Chronic Hemodialysis

1983 • 44 citations

Diurnal blood-pressure variations in haemodialysis and CAPD patients

1994 • 40 citations

Vascular Ca overload produced by vitamin D3 plus nicotine diminishes arterial distensibility in rats

1994 • 39 citations

Serum and Erythrocyte Tocopherol in Uremic Patients: Effect of Hemodialysis versus Peritoneal Dialysis

1993 • 39 citations

The effect of malnutrition on cardiovascular mortality in dialysis patients: is L-arginine the answer?

1994 • 38 citations

Uraemic medium causes endothelial cell dysfunction characterized by an alteration of the properties of its subendothelial matrix

1995 • 37 citations

1,25(OH)2D3 modulates intracellular Ca2+ and force generation in resistance arteries

1996 • 35 citations

Chairman's Workshop Report: Hypertension and cardiovascular effects--long-term safety and potential long-term benefits of r-HuEPO

1995 • 33 citations

Atherogenic lipid profile and lipoprotein(a) in relation to serum albumin in haemodialysis patients

1995 • 32 citations

No tissue level abnormality of vitamin A concentration despite elevated serum vitamin A of uremic patients.

1986 • 31 citations

Plasma Retinol and Retinol Binding Protein Concentrations in Patients on Maintenance Haemodialysis with and without Vitamin A Supplements

1982 • 29 citations

Vascular Consequences of Maintenance Hemodialysis – An Unproven Case

1978 • 28 citations

Alterations in soluble and leukocyte surface L-selectin (CD 62L) in hemodialysis patients.

1995 • 26 citations

Pathogenesis and Prevalence of Atherosclerosis in Hypertensive Patients

1994 • 26 citations

The effect of malnutrition on cardiovascular mortality in dialysis patients: is L-arginine the answer?

1994 • 24 citations

Correction by insulin of disturbed TG-rich LP metabolism in rats with chronic renal failure

1986 • 24 citations

Defect in cholesteryl ester transport in serum of patients with uremia receiving maintenance hemodialysis: increased inhibitor activity for cholesteryl ester transfer.

1988 • 22 citations

Chromosomal polymorphism in <i>Equus hemionu</i><i>s</i>

1978 • 20 citations

Atherogenesis—Is It Accelerated in Uremia?

1989 • 19 citations

Effect of Selective Serotonin Receptor Agonists on Prolactin Secretion in Male Rats

1993 • 18 citations

Decreased low-density lipoprotein receptor function and mRNA levels in lymphocytes from uremic patients

1992 • 18 citations

Defect in cholesterol transport in patients receiving maintenance hemodialysis.

1985 • 17 citations

Vascular endothelial dysfunction in patients on regular dialysis treatment.

1994 • 16 citations

Hemodialysis using high flux membranes improves lipid profiles.

1994 • 11 citations

Effect of apo B-containing lipoprotein particles on the progression of atherosclerotic lesions in the Monitored Atherosclerosis Regression Study (MARS)

1994 • 6 citations

Disturbances of apolipoprotein distribution in lipoproteins of uremic patients

1993 • 6 citations

[Isolated systolic hypertension in uremic hemodialyzed patients].

1991 • 5 citations

Treatment and prevention of hypertension: where have we been and where are we going?

1995 • 5 citations

Protection from atherosclerosis in vein graft by rigid external support

1992 • 5 citations

Niedermolekulares Heparin: Wie beeinflußt es den Fettstoffwechsel bei chronischen Hämodialysepatienten?

1991 • 4 citations