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Pathophysiological mechanisms of vascular calcification in end-stage renal disease

Data up to Jan 2025

Published2001
Citations248
References95

Total Citations Per Year

Abstract

References (95)

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Clinical epidemiology of cardiovascular disease in chronic renal disease

1998 • 3,896 citations

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1998 • 2,473 citations

Coronary-Artery Calcification in Young Adults with End-Stage Renal Disease Who Are Undergoing Dialysis

2000 • 2,426 citations

CORONARY-ARTERY CALCIFICATION IN YOUNG ADULTS WITH END-STAGE RENAL DISEASE WHO ARE UNDERGOING DIALYSIS

2000 • 2,241 citations

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

1997 • 2,050 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Accelerated Atherosclerosis in Prolonged Maintenance Hemodialysis

1974 • 1,789 citations

Coronary Artery Calcification: Pathophysiology, Epidemiology, Imaging Methods, and Clinical Implications

1996 • 1,066 citations

Bone morphogenetic protein expression in human atherosclerotic lesions.

1993 • 1,014 citations

Arterial stiffening and vascular calcifications in end‐stage renal disease

2000 • 991 citations

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques.

1993 • 642 citations

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

1994 • 616 citations

Re-evaluation of risks associated with hyperphosphatemia and hyperparathyroidism in dialysis patients: Recommendations for a change in management

2000 • 598 citations

Vascular Pericytes Express Osteogenic Potential In Vitro and In Vivo

1998 • 565 citations

Contribution of localized calcium deposits to dissection after angioplasty. An observational study using intravascular ultrasound.

1992 • 525 citations

Active Serum Vitamin D Levels Are Inversely Correlated With Coronary Calcification

1997 • 488 citations

Cardiac and arterial interactions in end-stage renal disease

1996 • 473 citations

Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain

1997 • 465 citations

Cellular Pathology As Based upon Physiological and Pathological Histology.

1972 • 460 citations

TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify.

1994 • 454 citations

Calcification of Vascular Smooth Muscle Cell Cultures

1999 • 446 citations

The Physiology of Parathyroid Hormone–Related Protein

2000 • 435 citations

Transcriptional control of osteoblast growth and differentiation

1996 • 426 citations

Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome

1999 • 388 citations

Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis.

1994 • 357 citations

Osteoprotegerin Is an αvβ3-induced, NF-κB-dependent Survival Factor for Endothelial Cells

2000 • 356 citations

Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques.

1994 • 314 citations

Arterial calcification and pathology in uremic patients undergoing dialysis

1979 • 297 citations

1,25-Dihydroxyvitamin D 3 Increases In Vitro Vascular Calcification by Modulating Secretion of Endogenous Parathyroid Hormone–Related Peptide

1998 • 294 citations

Ca2+ regulates fluid shear-induced cytoskeletal reorganization and gene expression in osteoblasts

2000 • 291 citations

β-Glycerophosphate Accelerates Calcification in Cultured Bovine Vascular Smooth Muscle Cells

1995 • 287 citations

The diagnostic and prognostic significance of coronary artery calcification. A report of 800 cases.

1980 • 275 citations

Cutaneous necrosis by calcific uremic arteriolopathy

2004 • 272 citations

Cardiovascular Risk Factors in Chronic Renal Failure and Hemodialysis Populations

1992 • 271 citations

THE PHYSIOLOGY OF PARATHYROID HORMONE-RELATED PROTEIN: An Emerging Role as a Developmental Factor

1998 • 268 citations

Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta.

1993 • 267 citations

Calcification of matrix vesicles in human aortic valve and aortic media.

1976 • 259 citations

Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques. A possible association with calcification.

1993 • 259 citations

Uremic small-artery disease with medial calcification and intimal hyperplasia (so-called calciphylaxis): A complication of chronic renal failure and benefit from parathyroidectomy

1995 • 258 citations

Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction

2000 • 247 citations

Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: A critical role for nuclear targeting

1997 • 240 citations

Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction

1988 • 215 citations

Advanced Glycation and Lipoxidation End Products

2000 • 206 citations

Calcification of Medial Elastic Fibers and Aortic Elasticity

1997 • 186 citations

A case control study of proximal calciphylaxis

1998 • 180 citations

Parathyroid Hormone–Related Peptide as a Local Regulator of Vascular Calcification

1997 • 173 citations

cAMP Stimulates Osteoblast-like Differentiation of Calcifying Vascular Cells

1998 • 169 citations

The Role of Gla Proteins in Vascular Calcification

1998 • 165 citations

Reconstitution of stretch-activated cation channels by expression of the α-subunit of the epithelial sodium channel cloned from osteoblasts

1997 • 155 citations

Type I collagen gene expression in human atherosclerosis. Localization to specific plaque regions.

1993 • 153 citations

Pericytes derived from the retinal microvasculature undergo calcification in vitro

1990 • 147 citations

1,25-Dihydroxyvitamin D3 stimulates the synthesis of matrix gamma-carboxyglutamic acid protein by osteosarcoma cells. Mutually exclusive expression of vitamin K-dependent bone proteins by clonal osteoblastic cell lines.

1988 • 140 citations

Oxford Textbook of Surgery

1995 • 134 citations

Aortic Calcification Produced by Vitamin D<sub>3</sub> plus Nicotine

1997 • 133 citations

Mechanically Strained Cells of the Osteoblast Lineage Organize Their Extracellular Matrix Through Unique Sites of αVβ3-Integrin Expression

2000 • 131 citations

Fibronectin and Collagen I Matrixes Promote Calcification of Vascular Cells in Vitro, Whereas Collagen IV Matrix Is Inhibitory

1998 • 123 citations

Accelerated Atherosclerosis in Chronic-Dialysis Patients – Another Look

1978 • 122 citations

Dexamethasone Enhances In Vitro Vascular Calcification by Promoting Osteoblastic Differentiation of Vascular Smooth Muscle Cells

1999 • 121 citations

Gene Expression during Vascular Pericyte Differentiation

1999 • 120 citations

Five cases of calciphylaxis and a review of the literature

1999 • 113 citations

Atherosclerotic calcification: Relation to developmental osteogenesis

1995 • 113 citations

Ethnic Origin and Serum Levels of 1α,25-Dihydroxyvitamin D 3 Are Independent Predictors of Coronary Calcium Mass Measured by Electron-Beam Computed Tomography

1997 • 112 citations

ACCELERATED ATHEROSCLEROSIS IN LONG-TERM DIALYSIS AND RENAL-TRANSPLANT PATIENTS: FACT OR FICTION?

1980 • 110 citations

Advanced Glycation Endproducts Accelerate Calcification in Microvascular Pericytes

1999 • 109 citations

Osteopontin stimulates gelsolin-associated phosphoinositide levels and phosphatidylinositol triphosphate-hydroxyl kinase.

1996 • 109 citations

Medial arterial calcification and diabetes mellitus

2000 • 106 citations

Expression of mineralisation-regulating proteins in association with human vascular calcification

2000 • 105 citations

Biotin- or digoxigenin-conjugated nucleotides bind to matrix vesicles in atherosclerotic plaques.

1996 • 99 citations

Matrix Gla protein synthesis and gamma-carboxylation in the aortic vessel wall and proliferating vascular smooth muscle cells--a cell system which resembles the system in bone cells.

1999 • 97 citations

Atherosclerosis in uremia: possible roles of hyperparathyroidism and intermediate density lipoprotein accumulation.

1997 • 88 citations

Calcifying Subpopulation of Bovine Aortic Smooth Muscle Cells Is Responsive to 17β-Estradiol

1997 • 80 citations

Induction of matrix gla protein synthesis during prolonged 1,25-Dihydroxyvitamin D3 treatment of osteosarcoma cells

1990 • 71 citations

Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells.

1996 • 65 citations

Cell differentiation in vascular calcification

2000 • 61 citations

Matrix Gla Protein Synthesis and Gamma-carboxylation in the Aortic Vessel Wall and Proliferating Vascular Smooth Muscle Cells

1999 • 56 citations

Mechanism of atherosclerotic calcification

2000 • 54 citations

Evidence That Implicates the Parathyroid Hormone–Related Peptide in Vascular Stenosis

1996 • 51 citations

New analogs of vitamin D3

1999 • 48 citations

The role of osteoprogenitors in vascular calcification

2000 • 47 citations

Receptors for parathyroid hormone and parathyroid hormone-related peptide: exploration of their biological importance

1999 • 46 citations

Tubular osteopontin expression in human glomerulonephritis and renal vasculitis

2000 • 45 citations

Analysis of regulatory regions in the COL1A1 gene responsible for 1,25‐dihydroxyvitamin D3‐mediated transcriptional repression in osteoblastic cells

1994 • 44 citations

Calcium-sensing receptor and calcimimetic agents

1999 • 42 citations

Phosphate binders on iron basis: A new perspective?

1999 • 36 citations

Arterial lesions of the radial artery in uraemic patients.

1979 • 35 citations

Calciphylaxis: a rare limb and life threatening cause of ischaemic skin necrosis and ulceration

2000 • 29 citations

Endogenous parathyroid hormone-related peptide enhances proliferation and inhibits differentiation in the osteoblast-like cell line ROS 17/2.8

2000 • 28 citations

Parathyroid hormone-related protein in the pancreatic islet and the cardiovascular system.

1998 • 24 citations

Amino-terminal fragment (1-34) of parathyroid hormone-related protein inhibits migration and proliferation of cultured vascular smooth muscle cells

1998 • 23 citations

Surgery for coronary artery disease.

1978 • 22 citations

Factors in the Differential Rate of Arteriosclerosis (AS) Between Long Surviving Renal Transplant Recipients And Dialysis Patients

1976 • 20 citations

Vascular smooth muscle and arterial calcification

2000 • 20 citations

Increased myogenic tone precedes structural changes in mild experimental uraemia in the absence of hypertension in rats

1998 • 10 citations

Vascular pericytes express osteogenic markers in vitro and form bone in vivo

1996 • 2 citations

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Pathophysiological mechanisms of vascular calcification in end-stage renal disease (2001) – Kidney International | Metascience Observatory Explorer