BMP-7 Is an Efficacious Treatment of Vascular Calcification in a Murine Model of Atherosclerosis and Chronic Renal Failure

Coronary-Artery Calcification in Young Adults with End-Stage Renal Disease Who Are Undergoing Dialysis

2000 • 2,426 citations

CORONARY-ARTERY CALCIFICATION IN YOUNG ADULTS WITH END-STAGE RENAL DISEASE WHO ARE UNDERGOING DIALYSIS

2000 • 2,241 citations

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Increased bone formation in osteocalcin-deficient mice

1996 • 1,692 citations

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage [published erratum appears in J Cell Biol 1995 Feb;128(4):following 713]

1994 • 1,442 citations

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

1995 • 1,118 citations

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.

1995 • 1,021 citations

Bone morphogenetic protein expression in human atherosclerotic lesions.

1993 • 1,014 citations

Arterial stiffening and vascular calcifications in end‐stage renal disease

2000 • 991 citations

Vascular Pericytes Express Osteogenic Potential In Vitro and In Vivo

1998 • 565 citations

Warfarin Causes Rapid Calcification of the Elastic Lamellae in Rat Arteries and Heart Valves

1998 • 531 citations

Contribution of localized calcium deposits to dissection after angioplasty. An observational study using intravascular ultrasound.

1992 • 525 citations

Cardiac and arterial interactions in end-stage renal disease

1996 • 473 citations

Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins

2002 • 451 citations

Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat.

1998 • 328 citations

Arterial calcification and pathology in uremic patients undergoing dialysis

1979 • 297 citations

Diet-induced Diabetes Activates an Osteogenic Gene Regulatory Program in the Aortas of Low Density Lipoprotein Receptor-deficient Mice

1998 • 248 citations

Pathophysiological mechanisms of vascular calcification in end-stage renal disease

2001 • 248 citations

Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction

2000 • 247 citations

Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification.

1994 • 244 citations

Loss of Tubular Bone Morphogenetic Protein—7 in Diabetic Nephropathy

2001 • 233 citations

BMP7 Null Mutation in Mice: Developmental Defects in Skeleton, Kidney, and Eye

1997 • 230 citations

Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy11Professor Robert Chevalier served as a guest editor for this paper.

2003 • 226 citations

The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression.

1994 • 223 citations

Bone Morphogenetic Protein-7 Improves Renal Fibrosis and Accelerates the Return of Renal Function

2002 • 222 citations

Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse development.

1995 • 180 citations

cAMP Stimulates Osteoblast-like Differentiation of Calcifying Vascular Cells

1998 • 169 citations

Cardiac hypertrophy and arterial alterations in end-stage renal disease: hemodynamic factors.

1993 • 166 citations

Pericytes derived from the retinal microvasculature undergo calcification in vitro

1990 • 147 citations

Transforming Growth Factor-β Induces Renal Epithelial Jagged-1 Expression in Fibrotic Disease

2002 • 144 citations

Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney

1999 • 143 citations

Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro

2000 • 142 citations

Chronic Uremia Induces Permeability Changes, Increased Nitric Oxide Synthase Expression, and Structural Modifications in the Peritoneum

2001 • 113 citations

Medial arterial calcification and diabetes mellitus

2000 • 106 citations

Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7

2002 • 94 citations

Crystal adsorption and growth slowing by nephrocalcin, albumin, and Tamm-Horsfall protein

1988 • 70 citations

Modified indirect immunodetection allows study of murine tissue with mouse monoclonal antibodies.

1994 • 67 citations

A reproducible model for chronic renal failure in the mouse

1983 • 57 citations

Surgery for coronary artery disease.

1978 • 22 citations

New approaches to delay the progression of chronic renal failure

2002 • 19 citations

Analysis of Expression of Genes Involved in Apolipoprotein E-Based Lipoprotein Metabolism in Pregnant Mice Deficient in the Receptor-Associated Protein, the Low Density Lipoprotein Receptor, or Apolipoprotein E1

1999 • 9 citations