Pathophysiology of Vascular Calcification in Chronic Kidney Disease

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2002 • 11,101 citations

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Clinical epidemiology of cardiovascular disease in chronic renal disease

1998 • 3,896 citations

Kidney Disease as a Risk Factor for Development of Cardiovascular Disease

2003 • 3,669 citations

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1998 • 2,473 citations

Coronary-Artery Calcification in Young Adults with End-Stage Renal Disease Who Are Undergoing Dialysis

2000 • 2,426 citations

Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: A national study

1998 • 2,334 citations

CORONARY-ARTERY CALCIFICATION IN YOUNG ADULTS WITH END-STAGE RENAL DISEASE WHO ARE UNDERGOING DIALYSIS

2000 • 2,241 citations

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

1997 • 2,050 citations

Death Risk in Hemodialysis Patients: The Predictive Value of Commonly Measured Variables and an Evaluation of Death Rate Differences Between Facilities

1990 • 1,983 citations

Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality

2003 • 1,778 citations

Goodpasture syndrome during the course of a Schönlein-Henoch purpura

2002 • 1,461 citations

Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients

2002 • 1,452 citations

Phosphate Regulation of Vascular Smooth Muscle Cell Calcification

2000 • 1,361 citations

Cardiac calcification in adult hemodialysis patients

2002 • 1,084 citations

Bone morphogenetic protein expression in human atherosclerotic lesions.

1993 • 1,014 citations

Arterial stiffening and vascular calcifications in end‐stage renal disease

2000 • 991 citations

Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study

2003 • 902 citations

The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification

2003 • 888 citations

C-reactive protein predicts all-cause and cardiovascular mortality in hemodialysis patients

2000 • 882 citations

Leptin and renal disease

2002 • 864 citations

Mineralized bone nodules formedin vitro from enzymatically released rat calvaria cell populations

1986 • 855 citations

Electron beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients

1996 • 794 citations

Atherosclerotic cardiovascular disease risks in chronic hemodialysis patients

2000 • 765 citations

Advanced Coronary and Carotid Arteriopathy in Young Adults With Childhood-Onset Chronic Renal Failure

2002 • 719 citations

Differential Expression of Bone Matrix Regulatory Proteins in Human Atherosclerotic Plaques

2001 • 703 citations

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques.

1993 • 642 citations

Medial Localization of Mineralization-Regulating Proteins in Association With Mönckeberg’s Sclerosis

1999 • 626 citations

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

1994 • 616 citations

Morphology of coronary atherosclerotic lesions in patients with end-stage renal failure

2000 • 611 citations

Lipid Oxidation Products Have Opposite Effects on Calcifying Vascular Cell and Bone Cell Differentiation

1997 • 602 citations

Traditional Cardiovascular Disease Risk Factors in Dialysis Patients Compared with the General Population

2002 • 592 citations

Aortic pulse wave velocity index and mortality in end-stage renal disease

2003 • 531 citations

Osteo/Chondrocytic Transcription Factors and Their Target Genes Exhibit Distinct Patterns of Expression in Human Arterial Calcification

2003 • 510 citations

Medial artery calcification in ESRD patients is associated with deposition of bone matrix proteins

2002 • 451 citations

Association Between Pulse Pressure and Mortality in Patients Undergoing Maintenance Hemodialysis

2002 • 393 citations

Aortic and large artery compliance in end-stage renal failure

1990 • 381 citations

Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis.

1994 • 357 citations

The Serum Protein α2-HS Glycoprotein/Fetuin Inhibits Apatite Formation in Vitro and in Mineralizing Calvaria Cells

1996 • 355 citations

Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells

2002 • 326 citations

Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels

2003 • 317 citations

Moderate renal insufficiency and the risk of cardiovascular mortality: Results from the NHANES I

2002 • 317 citations

Acta Chirurgica Scandinavica.

1930 • 307 citations

Arterial calcification and pathology in uremic patients undergoing dialysis

1979 • 297 citations

1,25-Dihydroxyvitamin D ₃ Increases In Vitro Vascular Calcification by Modulating Secretion of Endogenous Parathyroid Hormone–Related Peptide

1998 • 294 citations

THE CLINICAL EPIDEMIOLOGY OF CARDIOVASCULAR DISEASES IN CHRONIC KIDNEY DISEASE: Cardiovascular Disease in Chronic Renal Failure: Pathophysiologic Aspects

2003 • 290 citations

β-Glycerophosphate Accelerates Calcification in Cultured Bovine Vascular Smooth Muscle Cells

1995 • 287 citations

Hyperhomocysteinemia predicts cardiovascular outcomes in hemodialysis patients

2002 • 286 citations

Vascular Calcification

2003 • 285 citations

Fetuin/α2-HS Glycoprotein Is a Transforming Growth Factor-β Type II Receptor Mimic and Cytokine Antagonist

1996 • 253 citations

Cardiovascular disease risk factors in chronic renal insufficiency

2002 • 235 citations

Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells

2001 • 226 citations

Arterial calcification: A review of mechanisms, animal models, and the prospects for therapy

2001 • 221 citations

BMP-7 Is an Efficacious Treatment of Vascular Calcification in a Murine Model of Atherosclerosis and Chronic Renal Failure

2003 • 217 citations

Matrix GLA Protein Modulates Differentiation Induced by Bone Morphogenetic Protein-2 in C3H10T1/2 Cells

2001 • 210 citations

High-Density Lipoprotein Regulates Calcification of Vascular Cells

2002 • 206 citations

Parathyroid Hormone–Related Peptide as a Local Regulator of Vascular Calcification

1997 • 173 citations

Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats

2003 • 165 citations

Natural history of vascular calcification in dialysis and transplant patients

2004 • 165 citations

An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis

2002 • 164 citations

Sevelamer hydrochloride prevents ectopic calcification and renal osteodystrophy in chronic renal failure rats

2003 • 160 citations

Acetylated Low-Density Lipoprotein Stimulates Human Vascular Smooth Muscle Cell Calcification by Promoting Osteoblastic Differentiation and Inhibiting Phagocytosis

2002 • 153 citations

Assessment of vascular calcification in ESRD patients using spiral CT

2003 • 153 citations

Chronic Renal Failure Accelerates Atherogenesis in Apolipoprotein E–Deficient Mice

2003 • 151 citations

C-reactive protein and cardiovascular disease in peritoneal dialysis patients

2002 • 149 citations

Significant association between the progression of coronary artery calcification and dyslipidemia in patients on chronic hemodialysis

2001 • 148 citations

Management of Secondary Hyperparathyroidism: The Importance and the Challenge of Controlling Parathyroid Hormone Levels without Elevating Calcium, Phosphorus, and Calcium-Phosphorus Product

2003 • 146 citations

Regulation of Osteogenesis by Fetuin

1999 • 133 citations

The Effects of Sevelamer Hydrochloride and Calcium Carbonate on Kidney Calcification in Uremic Rats

2002 • 111 citations

Advanced Glycation Endproducts Accelerate Calcification in Microvascular Pericytes

1999 • 109 citations

The Effects of Sevelamer and Calcium Acetate on Proxies of Atherosclerotic and Arteriosclerotic Vascular Disease in Hemodialysis Patients

2003 • 107 citations

Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7

2002 • 94 citations

Cardiac calcification in renal patients: what we do and don't know

2004 • 83 citations

Serum calcium, phosphorus and albumin levels in relation to the angiographic severity of coronary artery disease

1997 • 81 citations

In subtotally nephrectomized rats 22-oxacalcitriol suppresses parathyroid hormone with less risk of cardiovascular calcification or deterioration of residual renal function than 1,25(OH)2 vitamin D3

2003 • 70 citations

Calciphylaxis and vascular calcification: a continuum of extra-skeletal osteogenesis

2003 • 66 citations

Systemic inhibition of spontaneous calcification by the serum protein alpha 2-HS glycoprotein/fetuin.

2001 • 65 citations

Antibody to oxidized low-density lipoprotein and cardiovascular mortality in end-stage renal disease

2002 • 55 citations

Vascular calcification in chronic kidney disease

2004 • 54 citations

Role of Lipoprotein (a) and TGF-β1 in Atherosclerosis of Hemodialysis Patients

2000 • 54 citations

THE CLINICAL EPIDEMIOLOGY OF CARDIOVASCULAR DISEASES IN CHRONIC KIDNEY DISEASE: Is Chronic Kidney Disease a Cardiovascular Disease Risk Factor?

2003 • 44 citations

Homocysteine potentiates calcification of cultured rat aortic smooth muscle cells

2003 • 39 citations

Arterial lesions of the radial artery in uraemic patients.

1979 • 35 citations

Matrix Gla Protein, a Marker of Vascular Calcification, in Hyperlipidemia

2003 • 3 citations