Immunoaffinity Purification and Functional Characterization of Human Transcription Factor IIH and RNA Polymerase II from Clonal Cell Lines That Conditionally Express Epitope-tagged Subunits of the Multiprotein Complexes

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

DNA EXCISION REPAIR

1996 • 1,127 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

RNA POLYMERASE II

1991 • 729 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 653 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Reversible Phosphorylation of the C-terminal Domain of RNA Polymerase II

1996 • 498 citations

BRCA1 is a component of the RNA polymerase II holoenzyme

1997 • 450 citations

Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

1992 • 407 citations

Temporal Regulation of RNA Polymerase II by Srb10 and Kin28 Cyclin-Dependent Kinases

1998 • 400 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.

1994 • 381 citations

Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II

1994 • 358 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

1994 • 325 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE.

1987 • 278 citations

Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation.

1995 • 263 citations

Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.

1995 • 239 citations

The multiple roles of transcription/repair factor TFIIH

1996 • 227 citations

Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

1992 • 219 citations

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.

1993 • 206 citations

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.

1993 • 206 citations

Taking a new TAK on Tat transactivation

1997 • 206 citations

A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators

1994 • 203 citations

Purification and interaction properties of the human RNA polymerase B(II) general transcription factor BTF2.

1991 • 202 citations

TAFII250 Is a Bipartite Protein Kinase That Phosphorylates the Basal Transcription Factor RAP74

1996 • 194 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity

1998 • 192 citations

Three transitions in the RNA polymerase II transcription complex during initiation

1997 • 181 citations

Regulation of CDK7 substrate specificity by MAT1 and TFIIH

1997 • 177 citations

Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: a model for promoter clearance.

1994 • 176 citations

Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription

1993 • 176 citations

RNA Polymerase II Subunit RPB4 Is Essential for High- and Low-Temperature Yeast Cell Growth

1989 • 173 citations

Purification of eukaryotic RNA polymerase II by immunoaffinity chromatography. Elution of active enzyme with protein stabilizing agents from a polyol-responsive monoclonal antibody.

1990 • 163 citations

Hepatitis B Virus pX Targets TFIIB in Transcription Coactivation

1998 • 145 citations

The role of Cdk7 in CAK function, a retro-retrospective

1998 • 145 citations

The multiple roles of transcription/repair factor TFIIH

1996 • 136 citations

RNA polymerase II subunit composition, stoichiometry, and phosphorylation.

1990 • 127 citations

A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes

1997 • 127 citations

Evidence for a mediator cycle at the initiation of transcription

1997 • 126 citations

Characterization of the Residues Phosphorylated in Vitro by Different C-terminal Domain Kinases

1998 • 126 citations

A Portion of RNA Polymerase II Molecules Has a Component Essential for Stress Responses and Stress Survival

1993 • 122 citations

A dynamic model for PC4 coactivator function in RNA polymerase II transcription

1998 • 121 citations

Identification of phosphorylation sites in the repetitive carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

1991 • 117 citations

The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

1995 • 113 citations

Transcription Elongation through DNA Arrest Sites

1997 • 111 citations

Transcription units as RNA processing units

1997 • 110 citations

Trajectory of DNA in the RNA polymerase II transcription preinitiation complex

1997 • 109 citations

The Role of Multisite Phosphorylation in the Regulation of RNA Polymerase II Activity

1994 • 100 citations

RNA polymerase II subunit RPB9 is required for accurate start site selection.

1995 • 100 citations

Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo

1998 • 95 citations

Yeast RNA polymerase II subunit RPB9 is essential for growth at temperature extremes.

1991 • 94 citations

Interaction of Elongation Factors TFIIS and Elongin A with a Human RNA Polymerase II Holoenzyme Capable of Promoter-specific Initiation and Responsive to Transcriptional Activators

1997 • 94 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE.

1990 • 84 citations

Purification of human RNA polymerase II and general transcription factors

1996 • 82 citations

RNA polymerases IIA and IIO have distinct roles during transcription from the TATA-less murine dihydrofolate reductase promoter.

1993 • 81 citations

Genes For Tfb2, Tfb3, and Tfb4 Subunits of Yeast Transcription/Repair Factor IIH

1997 • 79 citations

Interactions between the Human RNA Polymerase II Subunits

1997 • 77 citations

Promoter-proximal stalling results from the inability to recruit transcription factor IIH to the transcription complex and is a regulated event

1998 • 76 citations

Promoter escape limits the rate of RNA polymerase II transcription and is enhanced by TFIIE, TFIIH, and ATP on negatively supercoiled DNA

1998 • 74 citations

Phosphorylation negatively regulates the function of coactivator PC4.

1994 • 70 citations

The DNA-dependent ATPase activity associated with the class II basic transcription factor BTF2/TFIIH

1994 • 67 citations

Structure of wild-type yeast RNA polymerase II and location of Rpb4 and Rpb7

1998 • 62 citations

Promoter Escape by RNA Polymerase II A ROLE FOR AN ATP COFACTOR IN SUPPRESSION OF ARREST BY POLYMERASE AT PROMOTER-PROXIMAL SITES

1996 • 60 citations

Analysis of the Interaction of the Novel RNA Polymerase II (pol II) Subunit hsRPB4 with Its Partner hsRPB7 and with pol II

1998 • 56 citations

Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae

1996 • 56 citations

TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4

1998 • 49 citations

Properties of PC4 and an RNA Polymerase II Complex in Directing Activated and Basal Transcription in Vitro

1998 • 42 citations

Affinity Purification of Human DNA Repair/Transcription Factor TFIIH Using Epitope-tagged Xeroderma Pigmentosum B Protein

1998 • 35 citations

Immunoaffinity purification of RNA polymerase II and transcription factors using polyol-responsive monoclonal antibodies

1996 • 30 citations

Immunoaffinity Purification of the Human Multisubunit Transcription Factor IIH

1998 • 26 citations

Abortive Initiation and First Bond Formation at an Activated Adenovirus E4 Promoter

1995 • 24 citations

Establishment of Stable Cell Lines Expressing Potentially Toxic Proteins by Tetracycline-Regulated and Epitope-Tagging Methods

1996 • 22 citations

Rpb3, Stoichiometry and Sequence Determinants of the Assembly into Yeast RNA Polymerase II in Vivo

1998 • 17 citations

Repeated tertiary fold of RNA polymerase II and implications for DNA binding

1998 • 10 citations