Hepatitis B Virus pX Targets TFIIB in Transcription Coactivation

Antibodies, a laboratory manual

1989 • 12,929 citations

THE MOLECULAR BIOLOGY OF THE HEPATITIS B VIRUSES

1987 • 1,046 citations

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3.

1994 • 666 citations

HBV X Protein Alters the DNA Binding Specificity of CREB and ATF-2 by Protein-Protein Interactions

1991 • 457 citations

Woodchuck hepatitis virus X protein is required for viral infection in vivo

1994 • 443 citations

Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade.

1994 • 418 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks

1993 • 372 citations

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

1993 • 371 citations

The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors.

1995 • 311 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma.

1993 • 307 citations

Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation.

1995 • 263 citations

Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation

1995 • 250 citations

Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors

1990 • 247 citations

Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins

1996 • 237 citations

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication.

1995 • 234 citations

Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.

1993 • 229 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.

1993 • 206 citations

Hepatitis B virus transactivator protein X interacts with the TATA-binding protein.

1995 • 190 citations

Promoter-Selective Transcriptional Defect in Cell Cycle Mutant ts13 Rescued by hTAF _II 250

1994 • 163 citations

Hepatitis B Virus X Protein Is a Transcriptional Modulator That Communicates with Transcription Factor IIB and the RNA Polymerase II Subunit 5

1997 • 160 citations

TFG3/TAF30/ANC1, a Component of the Yeast SWI/SNF Complex That Is Similar to the Leukemogenic Proteins ENL and AF-9

1996 • 158 citations

Identification of a minimal set of proteins that is sufficient for accurate initiation of transcription by RNA polymerase II.

1993 • 148 citations

TFIIF-TAF-RNA polymerase II connection.

1994 • 148 citations

The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein.

1991 • 131 citations

Functional domains of transcription factor TFIIB.

1993 • 131 citations

Ras- and Raf-dependent activation of c-jun transcriptional activity by the hepatitis B virus transactivator pX.

1994 • 128 citations

Induction of the DNA-Binding Activity of c-Jun/c-Fos Heterodimers by the Hepatitis B Virus Transactivator pX

1994 • 127 citations

Hepatitis B virus X gene activates kappa B-like enhancer sequences in the long terminal repeat of human immunodeficiency virus 1.

1989 • 116 citations

pX, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner.

1996 • 102 citations

Identification of three essential regions of hepatitis B virus X protein for trans-activation function.

1992 • 99 citations

Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo.

1996 • 97 citations

The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element.

1990 • 94 citations

Multiple sets of basal factors initiate transcription by RNA polymerase II

1994 • 92 citations

DNA Template and Activator-Coactivator Requirements for Transcriptional Synergism by Drosophila Bicoid

1995 • 89 citations

The X Protein of Hepatitis B Virus Coactivates Potent Activation Domains

1995 • 88 citations

Distinct domains of hTAFII100 are required for functional interaction with transcription factor TFIIF beta (RAP30) and incorporation into the TFIID complex.

1996 • 87 citations

Interaction between a transcriptional activator and transcription factor IIB in vivo

1993 • 80 citations

Multiple regions of TBP participate in the response to transcriptional activators in vivo.

1994 • 67 citations

The identification of hepatitis B virus X gene responsive elements reveals functional similarity of X and HTLV-I tax.

1990 • 65 citations

Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation.

1995 • 59 citations

Two-Codon Insertion Mutations of the HBx Define Two Separate Regions Necessary for Its Trans-activation Function

1993 • 58 citations

Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae

1996 • 56 citations

Transactivation of Human Hepatitis B Virus X Protein, HBx, Operates through a Mechanism Distinct from Protein Kinase C and Okadaic Acid Activation Pathways

1994 • 55 citations

The hepatitis B virus transactivator HBx causes elevation of diacylglycerol and activation of protein kinase C

1993 • 42 citations

The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo.

1995 • 39 citations

A Direct Interaction between a Glutamine-Rich Activator and the N Terminus of TFIIB Can Mediate Transcriptional Activation In Vivo

1995 • 39 citations

Protease footprinting reveals a surface on transcription factor TFIIB that serves as an interface for activators and coactivators.

1995 • 37 citations

pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants

1998 • 31 citations

Three Sites of the Hepatitis B Virus X Protein Cooperatively Interact with Cellular Proteins

1994 • 28 citations

Modulation of intracellular signal transduction pathways by the hepatitis B virus transactivator pX.

1995 • 20 citations

Program of Research Workshop

1995 • 10 citations

Dynamics of interaction of RNA polymerase II with nucleosomes. II. During read‐through and elongation

1993 • 9 citations