TAFII-independent activation mediated by human TBP in the presence of the positive cofactor PC4

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 1,001 citations

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1997 • 905 citations

BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

1996 • 721 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

The role of general initiation factors in transcription by RNA polymerase II

1996 • 653 citations

Purification and properties of an ATP-dependent nucleosome remodeling factor

1995 • 600 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Eukaryotic Transcription: An Interlaced Network of Transcription Factors and Chromatin-Modifying Machines

1998 • 561 citations

The Enhanceosome and Transcriptional Synergy

1998 • 545 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.

1988 • 477 citations

Histone acetylation: chromatin in action

1997 • 475 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 471 citations

Repression and activation by multiprotein complexes that alter chromatin structure.

1996 • 444 citations

COMMON THEMES IN ASSEMBLY AND FUNCTION OF EUKARYOTIC TRANSCRIPTION COMPLEXES

1995 • 434 citations

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

1998 • 433 citations

The basics of basal transcription by RNA polymerase II

1994 • 409 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

DNA topoisomerase I is involved in both repression and activation of transcription

1993 • 380 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II

1994 • 358 citations

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.

1994 • 355 citations

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

1996 • 351 citations

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)

1990 • 346 citations

General Initiation Factors for RNA Polymerase II

1993 • 346 citations

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1996 • 341 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 334 citations

The Mechanism of Transcriptional Synergy of an In Vitro Assembled Interferon-β Enhanceosome

1997 • 333 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 299 citations

TBP-associated factors are not generally required for transcriptional activation in yeast

1996 • 289 citations

GAL4 derivatives function alone and synergistically with mammalian activators in vitro

1988 • 274 citations

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

1996 • 255 citations

Transcription activation in cells lacking TAFIIs

1996 • 238 citations

A role for nucleosome assembly in both silencing and activation of the Xenopus TR beta A gene by the thyroid hormone receptor.

1995 • 225 citations

Polymerase II Promoter Activation: Closed Complex Formation and ATP-Driven Start Site Opening

1992 • 220 citations

Taking a new TAK on Tat transactivation

1997 • 206 citations

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.

1993 • 206 citations

Activator-dependent regulation of transcriptional pausing on nucleosomal templates.

1996 • 205 citations

A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators

1994 • 203 citations

Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH

1997 • 195 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

1997 • 193 citations

NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro.

1996 • 188 citations

Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro.

1989 • 187 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification, Genetic Specificity, and TATA Box-Promoter Interactions of TFIID

1988 • 184 citations

The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein.

1994 • 174 citations

Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations.

1996 • 172 citations

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

1993 • 167 citations

Human cyclin-dependent kinase-activating kinase exists in three distinct complexes.

1996 • 164 citations

Promoter-Selective Transcriptional Defect in Cell Cycle Mutant ts13 Rescued by hTAF _II 250

1994 • 163 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly.

1990 • 162 citations

Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro.

1995 • 160 citations

Chromatin Structure and RNA Polymerase II Connection: Implications for Transcription

1996 • 159 citations

A Class of Activation Domains Interacts Directly with TFIIA and Stimulates TFIIA-TFIID-Promoter Complex Assembly

1995 • 152 citations

Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.

1994 • 151 citations

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1996 • 144 citations

Yeast TAFII145 Required for Transcription of G1/S Cyclin Genes and Regulated by the Cellular Growth State

1997 • 143 citations

The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA.

1995 • 143 citations

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.

1996 • 141 citations

Activation of the TFIID-TFIIA complex with HMG-2.

1995 • 139 citations

Protein–Protein Contacts that Activate and Repress Prokaryotic Transcription

1998 • 136 citations

Assembly of the isomerized TFIIA--TFIID--TATA ternary complex is necessary and sufficient for gene activation.

1996 • 136 citations

Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription.

1997 • 131 citations

Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.

1995 • 126 citations

A dynamic model for PC4 coactivator function in RNA polymerase II transcription

1998 • 121 citations

The Yeast TAF145 Inhibitory Domain and TFIIA Competitively Bind to TATA-Binding Protein

1998 • 119 citations

Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH.

1996 • 119 citations

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

1994 • 116 citations

The coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formation.

1995 • 113 citations

Binding of Basal Transcription Factor TFIIH to the Acidic Activation Domains of VP16 and p53

1994 • 112 citations

Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription

1997 • 111 citations

Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

1993 • 110 citations

The human general co-factors

1996 • 105 citations

NF-E2 Disrupts Chromatin Structure at Human β-Globin Locus Control Region Hypersensitive Site 2 In Vitro

1996 • 104 citations

Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation.

1994 • 103 citations

General Transcription Factors for RNA Polymerase II1

1997 • 102 citations

Transcription initiation by RNA polymerase II does not require hydrolysis of the beta-gamma phosphoanhydride bond of ATP.

1994 • 99 citations

Multiple sets of basal factors initiate transcription by RNA polymerase II

1994 • 92 citations

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

1993 • 88 citations

Expression and purification of general transcription factors by FLAG epitope-tagging and peptide elution.

1993 • 84 citations

Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.

1996 • 83 citations

Stimulation of RNA Polymerase II Elongation by Chromosomal Protein HMG-14

1994 • 83 citations

The ts13 Mutation in the TAF_II250 Subunit (CCG1) of TFIID Directly Affects Transcription of D-Type Cyclin Genes in Cells Arrested in G₁ at the Nonpermissive Temperature

1997 • 81 citations

HMG17 is a chromatin-specific transcriptional coactivator that increases the efficiency of transcription initiation.

1995 • 78 citations

TAFs: Guilt by Association?

1997 • 77 citations

Interactions between the Human RNA Polymerase II Subunits

1997 • 77 citations

The human general co-factors

1996 • 74 citations

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

1995 • 73 citations

Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.

1994 • 68 citations

Activator-dependent transcription by mammalian RNA polymerase II: In vitro reconstitution with general transcription factors and cofactors

1996 • 65 citations

RETRACTED: TAFIIs Mediate Activation of Transcription in the Drosophila Embryo

1996 • 64 citations

TAFIIs Mediate Activation of Transcription in theDrosophilaEmbryo

1998 • 61 citations

Analysis of the Interaction of the Novel RNA Polymerase II (pol II) Subunit hsRPB4 with Its Partner hsRPB7 and with pol II

1998 • 56 citations

Activation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro

1989 • 56 citations

Interaction of the Human T-Cell Lymphotropic Virus Type 1 Tax Transactivator with Transcription Factor IIA

1996 • 55 citations

Requirement for Transcription Factor IIA (TFIIA)-TFIID Recruitment by an Activator Depends on Promoter Structure and Template Competition

1997 • 53 citations

Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA.

1996 • 44 citations

Properties of PC4 and an RNA Polymerase II Complex in Directing Activated and Basal Transcription in Vitro

1998 • 42 citations

Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex

1996 • 37 citations

Biochemistry and Structural Biology of Transcription Factor IID (TFIID)

1996 • 34 citations

Establishment of Stable Cell Lines Expressing Potentially Toxic Proteins by Tetracycline-Regulated and Epitope-Tagging Methods

1996 • 22 citations

Common Themes in Assembly and Function of Eukaryotic Transcription Complexes

1995 • 20 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 12 citations

Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH.

1996 • 5 citations