Protein phosphorylation in neuronal plasticity and gene expression

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

1989 • 1,114 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

1994 • 959 citations

On target with a new mechanism for the regulation of protein phosphorylation

1993 • 901 citations

Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP

1994 • 889 citations

The Multifunctional Calcium/Calmodulin-Dependent Protein Kinase: From Form to Function

1995 • 812 citations

Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB

1994 • 732 citations

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity.

1994 • 718 citations

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras

1994 • 704 citations

An Essential Role for Protein Phosphatases in Hippocampal Long-Term Depression

1993 • 678 citations

Regulation of NMDA receptors by tyrosine kinases and phosphatases

1994 • 671 citations

Synaptic plasticity in the hippocampus: LTP and LTD

1994 • 653 citations

Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein

1995 • 615 citations

Mediation of Hippocampal Mossy Fiber Long-Term Potentiation by Cyclic AMP

1994 • 600 citations

Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

1994 • 542 citations

CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP

1995 • 530 citations

Dual role of calmodulin in autophosphorylation of multifunctional cam kinase may underlie decoding of calcium signals

1994 • 508 citations

cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase

1994 • 501 citations

Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase

1994 • 483 citations

Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation

1994 • 428 citations

Synaptic Desensitization of NMDA Receptors by Calcineurin

1995 • 404 citations

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

1994 • 394 citations

Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice.

1995 • 375 citations

Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons

1994 • 371 citations

CREB: A mediator of long-term memory from mollusks to mammals

1994 • 371 citations

Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation.

1994 • 370 citations

Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons

1993 • 353 citations

Potentiated Transmission and Prevention of Further LTP by Increased CaMKII activity in Postsynaptic Hippocampal Slice Neurons

1994 • 330 citations

The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B.

1994 • 314 citations

Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus.

1994 • 251 citations

Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A

1994 • 210 citations

Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin- dependent protein kinase II and protein kinase C in cultured hippocampal neurons

1994 • 188 citations

Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase.

1994 • 185 citations

Spatial and temporal changes in signal transduction pathways during LTP

1994 • 184 citations

The role of calcium–calmodulin kinase II in three forms of synaptic plasticity

1994 • 182 citations

Glutamate receptor phosphorylation and synaptic plasticity

1994 • 175 citations

Cyclic AMP and synaptic activity-dependent phosphorylation of AMPA- preferring glutamate receptors

1994 • 125 citations

Agonists and antagonists of protein kinase C function, derived from its binding proteins.

1994 • 125 citations

Rapid Translocation of Cytosolic Ca²⁺/Calmodulin‐Dependent Protein Kinase II into Postsynaptic Density After Decapitation

1994 • 115 citations

Nitric oxide and cGMP can produce either synaptic depression or potentiation depending on the frequency of presynaptic stimulation in the hippocampus

1994 • 114 citations

A rise in postsynaptic Ca 2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons

1994 • 113 citations

Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors.

1995 • 94 citations

Block of induction and maintenance of calcium-induced LTP by inhibition of protein kinase C in postsynaptic neuron in hippocampal CA1 region

1994 • 23 citations