An Essential Role for Protein Phosphatases in Hippocampal Long-Term Depression

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

1992 • 1,675 citations

Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1990 • 1,627 citations

Okadaic acid: a new probe for the study of cellular regulation

1990 • 1,396 citations

A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

1989 • 1,114 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

Calyculin A and okadaic acid: Inhibitors of protein phosphatase activity

1989 • 1,032 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation

1993 • 780 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

Mechanisms Underlying Long-Term Potentiation of Synaptic Transmission

1991 • 615 citations

Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases.

1990 • 589 citations

Persistent protein kinase activity underlying long-term potentiation

1988 • 557 citations

Protein Phosphorylation and Neuronal Function

1985 • 525 citations

Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II

1993 • 437 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II.

1993 • 402 citations

The Influence of Prior Synaptic Activity on the Induction of Long-Term Potentiation

1992 • 398 citations

Protein phosphatases: recent progress.

1991 • 391 citations

Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices

1991 • 356 citations

Postsynaptic factors control the duration of synaptic enhancement in area CA1 of the hippocampus

1991 • 319 citations

The effects of repetitive low frequency stimulation on control and “potentiated” synaptic responses in the hippocampus

1980 • 315 citations

Stable depression of potentiated synaptic responses in the hippocampus with 1–5 Hz stimulation

1990 • 303 citations

Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase

1993 • 294 citations

Feasibility of long-term storage of graded information by the Ca2+/calmodulin-dependent protein kinase molecules of the postsynaptic density.

1988 • 261 citations

Phosphorylation and Modulation of a Kainate Receptor (GluR6) by cAMP-Dependent Protein Kinase

1993 • 231 citations

and effects of protein phosphatase inhibitors, microcystins and nodularin, on mouse skin and fibroblasts

1990 • 197 citations

Persistent protein kinase activation in the maintenance phase of long-term potentiation.

1991 • 166 citations

Identification of protein phosphatase 1 in synaptic junctions: dephosphorylation of endogenous calmodulin-dependent kinase II and synapse-enriched phosphoproteins

1985 • 162 citations

Postsynaptic protein kinase C essential to induction and maintenance of long-term potentiation in the hippocampal CA1 region.

1992 • 157 citations

Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin.

1990 • 156 citations

Structure-activity relationship within a series of okadaic acid derivatives

1990 • 139 citations

Active site-directed inhibition of Ca2+/calmodulin-dependent protein kinase type II by a bifunctional calmodulin-binding peptide.

1988 • 94 citations

Serine/threonine phosphatases in the nervous system

1991 • 64 citations

Long-term depression: not so depressing after all.

1993 • 58 citations

Characterization of the integration time for the stabilization of long- term potentiation in area CA1 of the hippocampus

1992 • 55 citations