Boundaries and fields in early embryos

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

Ontogeny and Phylogeny

1977 • 3,887 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Models of biological pattern formation

1982 • 1,851 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

1984 • 1,066 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Expression of engrailed proteins in arthropods, annelids, and chordates

1989 • 1,019 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

1987 • 906 citations

Pattern Regulation in Epimorphic Fields

1976 • 871 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

Segmental patterns of neuronal development in the chick hindbrain

1989 • 840 citations

Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

1984 • 776 citations

Developmental Compartmentalisation of the Wing Disk of Drosophila

1973 • 770 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions

1990 • 685 citations

Molecular Genetics of the Bithorax Complex in Drosophila melanogaster

1983 • 616 citations

Materials for the study of variation

1894 • 597 citations

Genetic Control of Wing Disc Development in Drosophila

1975 • 584 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

Parasegments and compartments in the Drosophila embryo

1985 • 492 citations

Hox and HOM: Homologous gene clusters in insects and vertebrates

1989 • 467 citations

The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression

1985 • 456 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

Segmentation in the vertebrate nervous system

1984 • 440 citations

Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos

1987 • 437 citations

Control of compartment development by the engrailed gene in Drosophila

1975 • 429 citations

The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

1989 • 416 citations

Role of the Drosophila patched gene in positional signalling

1991 • 414 citations

Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein

1985 • 406 citations

Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development.

1988 • 393 citations

Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis

1988 • 383 citations

Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo

1988 • 381 citations

Compartments and Polyclones in Insect Development

1975 • 380 citations

The formation of mesodermal tissues in the mouse embryo during gastrulation and early organogenesis

1987 • 379 citations

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

1990 • 374 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

Genes controlling segmental specification in the Drosophila thorax.

1982 • 360 citations

Mechanisms of vertebrate segmentation

1988 • 356 citations

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

1989 • 348 citations

The molecular organization of the Antennapedia locus of drosophila

1983 • 331 citations

Experiments on the development of the fore limb of Amblystoma, a self‐differentiating equipotential system

1918 • 330 citations

Ontogeny and phylogeny

1978 • 304 citations

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system.

1990 • 299 citations

Roles of wingless in patterning the larval epidermis of Drosophila

1991 • 295 citations

Engrailed: a gene controlling compartment and segment formation in Drosophila.

1981 • 289 citations

Expression of engrailed during segmentation in grasshopper and crayfish

1989 • 288 citations

The generation of diversity and pattern in animal development

1992 • 284 citations

Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila.

1983 • 282 citations

The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.

1990 • 280 citations

Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila.

1987 • 276 citations

Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

1989 • 270 citations

Formation and regeneration of rhombomere boundaries in the developing chick hindbrain

1991 • 263 citations

A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo

1990 • 258 citations

Multiple modes of engrailed regulation in the progression towards cell fate determination

1991 • 248 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

Regulatory interactions between the segmentation genes fushi tarazu, hairy, and engrailed in the Drosophila blastoderm

1986 • 242 citations

Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even-skipped genes

1987 • 230 citations

Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes.

1987 • 220 citations

Expression of engrailed during segmentation in grasshopper and crayfish

1989 • 219 citations

The Elements of Experimental Embryology

1934 • 219 citations

Homoeotic and atavic mutations in insects

1977 • 214 citations

Multiple functions of segment polarity genes in Drosophila

1987 • 212 citations

Specification of limb development in the Drosophila embryo by positional cues from segmentation genes

1990 • 211 citations

The correct activation of Antennapedia and bithorax complex genes requires the fushi tarazu gene

1986 • 201 citations

Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped

1988 • 194 citations

Requirements for hedgehog, a segmental polarity gene, in patterning larval and adult cuticle of Drosophila.

1988 • 190 citations

Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene patched

1990 • 182 citations

Accumulation of collagen III at the cleft points of developing mouse submandibular epithelium

1988 • 181 citations

Gradients in the Insect Segment: The Orientation of Hairs in the Milkweed Bug Oncopeltus Fasciatus

1966 • 178 citations

Periodic segmental anomalies induced by heat shock in the chick embryo are associated with the cell cycle

1989 • 175 citations

A cell lineage analysis of segmentation in the chick embryo

1988 • 174 citations

The state of engrailed expression is not clonally transmitted during early Drosophila development

1992 • 173 citations

Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis

1986 • 171 citations

Targets of homeotic gene control in Drosophila

1990 • 159 citations

T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo

1991 • 158 citations

Hierarchical Inductions of Cell States: A Model for Segmentation in Drosophila

1986 • 157 citations

The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway

1987 • 141 citations

Homeotic genes and the control of segment diversity

1988 • 138 citations

The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells

1992 • 138 citations

Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the drosophila embryo

1990 • 137 citations

The embryonic origin of imaginal discs in Drosophila

1991 • 127 citations

Gradient fields and homeobox genes

1991 • 117 citations

Individual stripe regulatory elements in the Drosophila hairy promoter respond to maternal, gap, and pair-rule genes.

1991 • 117 citations

Pattern formation in the Drosophila embryo: allocation of cells to parasegments by even-skipped and fushi tarazu

1989 • 113 citations

The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells.

1992 • 109 citations

Molecular analysis of even-skipped mutants in Drosophila development.

1988 • 107 citations

The localized requirements for a gene affecting segmentation in Drosophila: Analysis of larvae mosaic for runt

1985 • 106 citations

Cell lineage and development in the larval epidermis ofDrosophila melanogaster

1979 • 100 citations

Beiträge zur Entwickelungsmechanik des Embryo

1888 • 100 citations

The spatial and temporal deployment ofDfdandScrtranscripts throughout development ofDrosophila

1987 • 99 citations

Region-specific alleles of the Drosophila segmentation gene hairy.

1988 • 91 citations

The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway.

1987 • 91 citations

Development of segmentation in zebrafish

1988 • 90 citations

The Development of Patterns in the Integument of Insects

1967 • 89 citations

Decoding positional information: regulation of the pair-rule gene hairy

1990 • 86 citations

Mechanism by which Cells estimate their Location within the Body

1966 • 83 citations

Segment polarity genes and cell patterning within the Drosophila body segment

1991 • 81 citations

Isolation of an abdominal-A gene from the locust Schistocerca gregaria and its expression during early embryogenesis

1990 • 75 citations

Molecular Aspects of Early Development

1984 • 64 citations

Imaginal discs can be recovered from cultured embryos mutant for the segment-polarity genes engrailed, naked and patched but not from wingless

1989 • 62 citations

Pattern stability in the insect segment

1977 • 60 citations

Dose-dependent regulation of pair-rule stripes by gap proteins and the initiation of segment polarity

1990 • 59 citations

The Wnt-1 (int-1) Oncogene Promoter and Its Mechanism of Activation by Insertion of Proviral DNA of the Mouse Mammary Tumor Virus

1990 • 59 citations

Functional dissection of the paired segmentation gene in Drosophila embryos.

1991 • 49 citations

A cellular basis for pattern formation in the insect epidermis

1989 • 39 citations

The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus.

1990 • 38 citations

Pattern stability in the insect segment

1979 • 38 citations

Homoeotic Genes and the Specification of Segmental Identity in the Embryo and Adult Thorax of Drosophila Melanogaster

1984 • 34 citations

Unrestricted expression of the Drosophila gene patched allows a normal segment polarity

1991 • 30 citations

Segmental polarity and identity in the abdomen of Drosophila is controlled by the relative position of gap gene expression

1989 • 18 citations

Segments, lineage boundaries and the domains of expression of homeotic genes

1985 • 14 citations