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A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo

Data up to Jan 2025

Published1990
Citations258
References26

Total Citations Per Year

Abstract

References (26)

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner

1988 • 1,022 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo

1989 • 672 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

Determination of Anteroposterior Polarity in Drosophila

1987 • 651 citations

Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophila

1986 • 463 citations

Specification of the Basic Body Pattern in Insect Embryogenesis

1976 • 436 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Regulation of the Drosophila segmentation gene hunchback by two maternal morphogenetic centres

1988 • 366 citations

Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations

1990 • 340 citations

The Drosophila posterior-group gene nanos functions by repressing hunchback activity

1989 • 301 citations

hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo

1987 • 289 citations

Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos

1989 • 222 citations

Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps

1988 • 217 citations

Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene

1989 • 198 citations

Structure of the Drosophila BicaudalD protein and its role in localizing the posterior determinant nanos

1989 • 185 citations

Cross-regulatory interactions among the gap genes of Drosophila

1986 • 168 citations

Differential regulation of the two transcripts from the Drosophila gap segmentation gene hunchback.

1988 • 149 citations

Krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the Drosophila embryo

1989 • 140 citations

GENETIC ANALYSIS OF THREE DOMINANT FEMALE-STERILE MUTATIONS LOCATED ON THE X CHROMOSOME OF DROSOPHILA MELANOGASTER

1983 • 132 citations

Pole region-dependent repression of the Drosophila gap gene Krüppel by maternal gene products

1987 • 124 citations

Genetic analysis of pattern-formation in the embryo ofDrosophila melanogaster

1977 • 115 citations

Segmental polarity and identity in the abdomen of Drosophila is controlled by the relative position of gap gene expression

1989 • 18 citations

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A morphogenetic gradient of hunchback protein organizes the expression of the gap genes… (1990) – Nature | Metascience Observatory Explorer