Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

2001 • 3,867 citations

Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

2002 • 1,443 citations

BAX and BAK Regulation of Endoplasmic Reticulum Ca ²⁺ : A Control Point for Apoptosis

2003 • 1,363 citations

Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis

1999 • 1,255 citations

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

2005 • 1,169 citations

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria.

1982 • 1,152 citations

Cytosol-to-membrane redistribution of Bax and Bcl-X_Lduring apoptosis

1997 • 1,117 citations

A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

2002 • 1,015 citations

Cytochrome c release from mitochondria proceeds by a two-step process

2002 • 917 citations

Lipids of mitochondria

1985 • 842 citations

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

2002 • 801 citations

Caspase-independent cell death

2005 • 699 citations

The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

2002 • 695 citations

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

2000 • 619 citations

Regulated Targeting of BAX to Mitochondria

1998 • 617 citations

IMPORT OF PROTEINS INTO MITOCHONDRIA

1991 • 583 citations

Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario

2006 • 569 citations

Dnm1 forms spirals that are structurally tailored to fit mitochondria

2005 • 554 citations

Role of curvature and phase transition in lipid sorting and fission of membrane tubules

2005 • 466 citations

Cardiolipin provides specificity for targeting of tBid to mitochondria

2000 • 462 citations

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

2006 • 448 citations

Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes

2007 • 366 citations

Cardiolipin: Setting the beat of apoptosis

2007 • 283 citations

Lipidic Pore Formation by the Concerted Action of Proapoptotic BAX and tBID

2004 • 234 citations

Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature

2002 • 229 citations

Inhibiting the Mitochondrial Fission Machinery Does Not Prevent Bax/Bak-Dependent Apoptosis

2006 • 224 citations

Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein

2002 • 192 citations

Bid-Cardiolipin Interaction at Mitochondrial Contact Site Contributes to Mitochondrial Cristae Reorganization and CytochromecRelease

2004 • 157 citations

Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

2001 • 148 citations

TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax

2006 • 147 citations

Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis

2006 • 144 citations

Proapoptotic Bid binds to monolysocardiolipin, a new molecular connection between mitochondrial membranes and cell death

2003 • 125 citations

Bax activation and stress-induced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes

2007 • 125 citations

Tumor Necrosis Factor-related Apoptosis-inducing Ligand Activates a Lysosomal Pathway of Apoptosis That Is Regulated by Bcl-2 Proteins

2007 • 123 citations

Two eukaryote-specific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast

1996 • 114 citations

Phospholipid asymmetry of the outer membrane of rat liver mitochondria

1993 • 98 citations

Regulation of Bcl-2 proteins and of the permeability of the outer mitochondrial membrane

2005 • 96 citations

Identification and functional characterization of hCLS1, a human cardiolipin synthase localized in mitochondria

2006 • 93 citations

Cardiolipin Is Not Required for Bax-mediated Cytochrome c Release from Yeast Mitochondria

2004 • 74 citations

The N-terminal conformation of Bax regulates cell commitment to apoptosis

2007 • 57 citations

Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells

2006 • 57 citations

Phosphorylation of mitochondrial phospholipid scramblase 3 by protein kinase C‐δ induces its activation and facilitates mitochondrial targeting of tBid

2007 • 48 citations

Capillary electrophoresis of cardiolipin with on‐line dye interaction and spectrophotometric detection

2003 • 31 citations

Bax Function in the Absence of Mitochondria in the Primitive Protozoan Giardia lamblia

2007 • 16 citations