Proapoptotic Bid binds to monolysocardiolipin, a new molecular connection between mitochondrial membranes and cell death

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

2001 • 3,867 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

The expanding role of mitochondria in apoptosis.

2001 • 2,377 citations

Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

2002 • 1,443 citations

Mitochondria

2003 • 1,233 citations

Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death

1999 • 1,024 citations

A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

2002 • 1,015 citations

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1999 • 999 citations

Cytochrome c release from mitochondria proceeds by a two-step process

2002 • 917 citations

The biosynthesis and functional role of cardiolipin

2000 • 786 citations

Nonionic Detergents Induce Dimerization among Members of the Bcl-2 Family

1997 • 583 citations

Posttranslational N-Myristoylation of BID as a Molecular Switch for Targeting Mitochondria and Apoptosis

2000 • 555 citations

Cardiolipin provides specificity for targeting of tBid to mitochondria

2000 • 462 citations

Phosphorylation of Bid by Casein Kinases I and II Regulates Its Cleavage by Caspase 8

2001 • 341 citations

Detection of Individual Phospholipids in Lipid Mixtures by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry: Phosphatidylcholine Prevents the Detection of Further Species

2001 • 308 citations

Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.

1995 • 295 citations

Cardiolipin and apoptosis

2002 • 260 citations

Fas-induced Arachidonic Acid Release Is Mediated by Ca2+-independent Phospholipase A2 but Not Cytosolic Phospholipase A2, Which Undergoes Proteolytic Inactivation

1998 • 231 citations

Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature

2002 • 229 citations

The roles of Bid.

2002 • 220 citations

A fluorescently labeled intestinal fatty acid binding protein. Interactions with fatty acids and its use in monitoring free fatty acids.

1992 • 215 citations

The Apoptotic Protein tBid Promotes Leakage by Altering Membrane Curvature

2002 • 166 citations

tBID Homooligomerizes in the Mitochondrial Membrane to Induce Apoptosis

2002 • 158 citations

The binding of lysophospholipids to rat liver fatty acid-binding protein and albumin

1994 • 137 citations

Relief of Extrinsic Pathway Inhibition by the Bid-dependent Mitochondrial Release of Smac in Fas-mediated Hepatocyte Apoptosis

2002 • 134 citations

Bid, a Widely Expressed Proapoptotic Protein of the Bcl-2 Family, Displays Lipid Transfer Activity

2001 • 130 citations

Cytochrome c Release upon Fas Receptor Activation Depends on Translocation of Full-length Bid and the Induction of the Mitochondrial Permeability Transition

2002 • 129 citations

The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment

2000 • 126 citations

Lysocardiolipin formation and reacylation in isolated rat liver mitochondria

1990 • 118 citations

Acylation of monolysocardiolipin in rat heart

1999 • 80 citations

Intramolecularly Quenched BODIPY-Labeled Phospholipid Analogs in Phospholipase A2 and Platelet-Activating Factor Acetylhydrolase Assays and in Vivo Fluorescence Imaging

1999 • 74 citations

BID-D59A Is a Potent Inducer of Apoptosis in Primary Embryonic Fibroblasts

2003 • 69 citations

Mitochondrial Lipid Alterations during Fas- and Radiation-Induced Apoptosis

2001 • 69 citations

Acyl Coenzyme A Binding Protein

1998 • 68 citations

Lipids, cardiolipin and apoptosis: a greasy licence to kill

2002 • 61 citations

Binding of two mono‐acylated lipid monomers by the barley lipid transfer protein, LTP1, as viewed by fluorescence, isothermal titration calorimetry and molecular modelling

2001 • 59 citations

Quenching of the intrinsic tryptophan fluorescence of mitochondrial ubiquinol—cytochrome‐c reductase by the binding of ubiquinone

1988 • 51 citations

Bax, along with Lipid Conspirators, Allows Cytochrome c to Escape Mitochondria

2002 • 42 citations

Limited Proteolysis of Rat Phosphatidylinositol Transfer Protein by Trypsin Cleaves the C Terminus, Enhances Binding to Lipid Vesicles, and Reduces Phospholipid Transfer Activity

1996 • 33 citations

Inhibition of mitochondrial phospholipase A2 by mono- and dilysocardiolipin

1987 • 16 citations

A quantitative electrophoretic migration shift assay for analyzing the specific binding of proteins to lipid ligands in vesicles or micelles

1995 • 15 citations

PHOSPHOLIPIDS REACYLATION AND PALMITOYLCOA CONTROL TUMOUR NECROSIS FACTOR-α SENSITIVITY

2001 • 3 citations