Back to search

A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

Data up to Jan 2025

Published2002
Citations1,015
References43

Total Citations Per Year

Abstract

References (43)

Mitochondria and Apoptosis

1998 • 8,909 citations

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

2001 • 3,867 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

The mitochondrial permeability transition

1995 • 2,412 citations

THE MITOCHONDRIAL DEATH/LIFE REGULATOR IN APOPTOSIS AND NECROSIS

1998 • 1,982 citations

BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

2001 • 1,672 citations

The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

2001 • 1,663 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Mitochondrial Transport of Cations: Channels, Exchangers, and Permeability Transition

1999 • 1,509 citations

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

1998 • 1,381 citations

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

2000 • 1,245 citations

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

2000 • 1,046 citations

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1999 • 999 citations

ULTRASTRUCTURAL BASES FOR METABOLICALLY LINKED MECHANICAL ACTIVITY IN MITOCHONDRIA

1966 • 947 citations

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

2001 • 815 citations

The internal structure of mitochondria

2000 • 810 citations

Mitochondria and cell death

1999 • 763 citations

Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence

1999 • 664 citations

Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg2+ Ions

1998 • 645 citations

Posttranslational N-Myristoylation of BID as a Molecular Switch for Targeting Mitochondria and Apoptosis

2000 • 555 citations

Interactions of Cyclophilin with the Mitochondrial Inner Membrane and Regulation of the Permeability Transition Pore, a Cyclosporin A-sensitive Channel

1996 • 460 citations

PHOSPHORYLATION COUPLED TO OXIDATION OF DIHYDRODIPHOSPHOPYRIDINE NUCLEOTIDE

1951 • 423 citations

The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol

1999 • 316 citations

Mitochondrial Proliferation and Paradoxical Membrane Depolarization during Terminal Differentiation and Apoptosis in a Human Colon Carcinoma Cell Line

1997 • 311 citations

Double-tilt electron tomography

1995 • 311 citations

Proapoptotic BH3-only Bcl-2 family members induce cytochromecrelease, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity

2000 • 273 citations

Imaging the Permeability Pore Transition in Single Mitochondria

1998 • 269 citations

Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release

2000 • 244 citations

Weighted Back-projection Methods

2008 • 239 citations

Topology of the Mitochondrial Inner Membrane: Dynamics and Bioenergetic Implications

2001 • 238 citations

The inner mitochondrial membrane contains ion‐conducting channels similar to those found in bacteria

1989 • 224 citations

Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes.

1981 • 203 citations

A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c

2001 • 156 citations

Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochrome b of the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

2000 • 86 citations

The action of digitonin on rat liver mitochondria. The effects on enzyme content

1968 • 82 citations

Sterecon—Three-Dimensional Reconstructions from Stereoscopic Contouring

1996 • 49 citations

Quantitative cytochemistry of the diaminobenzidine cytochrome oxidase reaction product in mitochondria of cardiac muscle and pancreas.

1983 • 47 citations

Biophysical and morphological correlates of kinetic change and death in a starved human melanoma cell line

1981 • 46 citations

Organelle division: Self-assembling GTPases caught in the middle

2000 • 43 citations

Rate-limiting Step Preceding Cytochrome c Release in Cells Primed for Fas-mediated Apoptosis Revealed by Analysis of Cellular Mosaicism of Respiratory Changes

2001 • 30 citations

Pathways of cytochrome c oxidation by soluble and membrane-bound cytochrome aa3

1980 • 25 citations

[Mitochondrial transport of cations].

1988 • 11 citations

Cited By (0)

No citing papers found in database

A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during… (2002) – Developmental Cell | Metascience Observatory Explorer