Molecular Significance of Excess Body Weight in Postmenopausal Breast Cancer Patients, in Relation to Expression of Insulin‐like Growth Factor I Receptor and Insulin‐like Growth Factor II Genes

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1998 • 1,850 citations

Dual Effects of Weight and Weight Gain on Breast Cancer Risk

1997 • 813 citations

A Prospective Study of Endogenous Estrogens and Breast Cancer in Postmenopausal Women

1995 • 635 citations

Alcohol, Height, and Adiposity in Relation to Estrogen and Prolactin Levels in Postmenopausal Women

1995 • 556 citations

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor.

1993 • 554 citations

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.

1994 • 527 citations

Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation.

1997 • 343 citations

A Large‐scale, Hospital‐based Case‐Control Study of Risk Factors of Breast Cancer According to Menopausal Status

1995 • 297 citations

A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor.

1994 • 282 citations

Two insulin-like growth factor I messenger RNAs are expressed in human liver.

1986 • 260 citations

Insulin-Like Growth Factor-ll (IGF-II): A Potential Autocrine/Paracrine Growth Factor for Human Breast Cancer Acting via the IGF-I Receptor

1989 • 248 citations

Body Size and Risk of Breast Cancer

1997 • 218 citations

Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast.

1998 • 209 citations

Growth factor messenger RNA expression by human breast fibroblasts from benign and malignant lesions.

1991 • 204 citations

Insulin-like Growth Factor-I Induces bcl-2 Promoter through the Transcription Factor cAMP-Response Element-binding Protein

1999 • 200 citations

Obesity at Diagnosis of Breast Carcinoma Influences Duration of Disease-free Survival

1992 • 183 citations

Insulin-like Growth Factor Expression in Human Cancer Cell Lines

1996 • 179 citations

The Role of Body Mass Index in the Relative Risk of Developing Premenopausal versus Postmenopausal Breast Cancer

1997 • 165 citations

Type I Insulin-like Growth Factor Receptor Activation Regulates Apoptotic Proteins

1996 • 162 citations

Effect of a Null Mutation of the Insulin-Like Growth Factor I Receptor Gene on Growth and Transformation of Mouse Embryo Fibroblasts

1994 • 162 citations

p53 Regulates Insulin-Like Growth Factor-I (IGF-I) Receptor Expression and IGF-I-Induced Tyrosine Phosphorylation in an Osteosarcoma Cell Line: Interaction between p53 and Sp1

1998 • 151 citations

OVERWEIGHT AND CHANGES IN WEIGHT THROUGHOUT ADULT LIFE IN BREAST CANCER ETIOLOGY

1985 • 150 citations

Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways.

1998 • 149 citations

Insulin-Like Growth Factor-I in Relation to Premenopausal Ductal Carcinoma in Situ of the Breast

1998 • 146 citations

Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: evidence for paracrine function.

1995 • 134 citations

Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid.

1995 • 126 citations

Cardiovascular diseases and diabetes mellitus in different ethnic groups: the Finnmark study.

1998 • 110 citations

Body size indices and breast cancer risk before and after menopause

1996 • 109 citations

Body mass index and post-menopausal breast cancer: an age-specific analysis

1997 • 104 citations

The effect of body mass index and oestrogen receptor level on survival of breast cancer patients

1997 • 84 citations

Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro.

1994 • 79 citations

Survival of breast‐cancer patients and body size indicators

1990 • 78 citations

Obesity and body fat distribution and breast cancer prognosis

1991 • 71 citations

A Functional Insulin-Like Growth Factor I Receptor Is Required for the Mitogenic and Transforming Activities of the Epidermal Growth Factor Receptor

1994 • 69 citations

Specific Decrease in Liver Insulin-Like Growth Factor-I and Brain Insulin-Like Growth Factor-II Gene Expression in Energy-Restricted Rats

1991 • 65 citations

Two promoters in expression of estrogen receptor messenger RNA in human breast cancer

1997 • 58 citations

Insulin-like Growth Factor-1 Receptor and Its Ligand Regulate the Reentry of Adult Ventricular Myocytes into the Cell Cycle

1997 • 55 citations

Abnormal FHIT transcripts in human breast carcinomas: a clinicopathological and epidemiological analysis of 61 Japanese cases.

1997 • 50 citations

Effects of acute and chronic food restriction on the insulin-like growth factor axis in the guinea pig

1998 • 41 citations

Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid

1995 • 34 citations

Paradoxical effects of overexpression of the type I insulin-like growth factor (IGF) receptor on the responsiveness of human breast cancer cells to IGFs and estradiol.

1996 • 34 citations

Regulation of Insulin-Like Growth Factor I Receptor Promoter Activity by Wild-Type and Mutant Versions of the WT1 Tumor Suppressor¹

1999 • 33 citations

Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro

1994 • 28 citations

Regulation of Insulin-Like Growth Factor I Receptor Promoter Activity by Wild-Type and Mutant Versions of the WT1 Tumor Suppressor

1999 • 15 citations

Paradoxical effects of overexpression of the type I insulin-like growth factor (IGF) receptor on the responsiveness of human breast cancer cells to IGFs and estradiol

1996 • 10 citations