Endoglin Regulates Cytoskeletal Organization through Binding to ZRP-1, a Member of the Lim Family of Proteins

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

1994 • 1,452 citations

Hereditary Hemorrhagic Telangiectasia

1995 • 1,052 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Defective Angiogenesis in Mice Lacking Endoglin

1999 • 851 citations

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.

1992 • 837 citations

LIM domains: multiple roles as adapters and functional modifiers in protein interactions

1998 • 592 citations

Endoglin Is an Accessory Protein That Interacts with the Signaling Receptor Complex of Multiple Members of the Transforming Growth Factor-β Superfamily

1999 • 562 citations

A murine model of hereditary hemorrhagic telangiectasia

1999 • 472 citations

Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.

1990 • 450 citations

Endoglin, an Ancillary TGFβ Receptor, Is Required for Extraembryonic Angiogenesis and Plays a Key Role in Heart Development

2000 • 433 citations

Rare diseases bullet 4: Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations: issues in clinical management and review of pathogenic mechanisms

1999 • 365 citations

Role of Proteins of the Ena/VASP Family in Actin-based Motility of Listeria monocytogenes

1999 • 356 citations

Endoglin modulates cellular responses to TGF-beta 1.

1996 • 306 citations

Microfilament Structure and Function in the Cortical Cytoskeleton

1991 • 276 citations

Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line.

1988 • 256 citations

CD105 antagonizes the inhibitory signaling of transforming growth factor βl on human vascular endothelial cells

2000 • 232 citations

Role of Endoglin in Cellular Responses to Transforming Growth Factor-β

1998 • 223 citations

Regulated expression on human macrophages of endoglin, an Arg‐Gly‐Asp‐containing surface antigen

1992 • 222 citations

Zyxin: Zinc fingers at sites of cell adhesion

1997 • 213 citations

Identification and expression of two forms of the human transforming growth factor‐β‐binding protein endoglin with distinct cytoplasmic regions

1993 • 212 citations

LPP,the Preferred Fusion Partner Gene ofHMGICin Lipomas, Is a Novel Member of the LIM Protein Gene Family

1996 • 196 citations

Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta.

1994 • 193 citations

Characterization of the Interaction between Zyxin and Members of the Ena/Vasodilator-stimulated Phosphoprotein Family of Proteins

2000 • 165 citations

Zyxin and paxillin proteins: focal adhesion plaque LIM domain proteins go nuclear

2003 • 155 citations

Targeting of Zyxin to Sites of Actin Membrane Interaction and to the Nucleus

2001 • 155 citations

LPP, an Actin Cytoskeleton Protein Related to Zyxin, Harbors a Nuclear Export Signal and Transcriptional Activation Capacity

2000 • 154 citations

Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells.

1994 • 133 citations

Endoglin Controls Cell Migration and Composition of Focal Adhesions

2004 • 123 citations

ActA and human zyxin harbour Arp2/3-independent actin-polymerization activity

2001 • 119 citations

Molecular Characterization of Human Zyxin

1996 • 112 citations

Endoglin, a TGF-beta receptor-associated protein, is expressed by smooth muscle cells in human atherosclerotic plaques

2000 • 112 citations

Molecular Dissection of Zyxin Function Reveals Its Involvement in Cell Motility

1999 • 110 citations

Members of the Zyxin Family of LIM Proteins Interact with Members of the p130Cas Family of Signal Transducers

2002 • 109 citations

Using the yeast two‐hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth

1998 • 106 citations

An α-Actinin Binding Site of Zyxin Is Essential for Subcellular Zyxin Localization and α-Actinin Recruitment

1999 • 105 citations

Doing (F/L)pppps: EVH1 domains and their proline-rich partners in cell polarity and migration

2002 • 104 citations

Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion

2002 • 103 citations

Endoglin overexpression modulates cellular morphology, migration, and adhesion of mouse fibroblasts

1999 • 99 citations

TRIP6 Enhances Lysophosphatidic Acid-induced Cell Migration by Interacting with the Lysophosphatidic Acid 2 Receptor

2004 • 89 citations

Expression of Endoglin mRNA and Protein in Human Vascular Smooth Muscle Cells

1998 • 86 citations

Molecular cloning and characterization of the human and porcine transforming growth factor-β type III receptors

1992 • 85 citations

Structural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes

1997 • 84 citations

LIM domain protein Trip6 has a conserved nuclear export signal, nuclear targeting sequences, and multiple transactivation domains

2001 • 84 citations

The HumanTRIP6Gene Encodes a LIM Domain Protein and Maps to Chromosome 7q22, a Region Associated with Tumorigenesis

1998 • 80 citations

Endoglin Is Overexpressed After Arterial Injury and Is Required for Transforming Growth Factor-β–Induced Inhibition of Smooth Muscle Cell Migration

2000 • 79 citations

The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL

2000 • 70 citations

Expression analysis of endoglin missense and truncation mutations: insights into protein structure and disease mechanisms

2000 • 65 citations

Mapping epitopes to distinct regions of the extracellular domain of endoglin using bacterially expressed recombinant fragments

1997 • 63 citations

Distribution of endoglin in early human development reveals high levels on endocardial cushion tissue mesenchyme during valve formation

1998 • 62 citations

Vasodilator-Stimulated Phosphoprotein Is Involved in Stress-Fiber and Membrane Ruffle Formation in Endothelial Cells

2000 • 55 citations

Molecules in focus The focal adhesion phosphoprotein, VASP

1998 • 53 citations

ZRP-1, a Zyxin-related Protein, Interacts with the Second PDZ Domain of the Cytosolic Protein Tyrosine Phosphatase hPTP1E

1999 • 52 citations

Role of Zyxin in Differential Cell Spreading and Proliferation of Melanoma Cells and Melanocytes

2002 • 46 citations

Characterization of mouse Trip6: a putative intracellular signaling protein

1999 • 43 citations

Nuclear Localization Signal of Murine CMP-Neu5Ac Synthetase Includes Residues Required for Both Nuclear Targeting and Enzymatic Activity

2002 • 38 citations

LIM domain-containing protein trip6 can act as a coactivator for the v-Rel transcription factor.

1999 • 36 citations

A Zyxin‐Related Protein whose Synthesis is Reduced in Virally Transformed Fibroblasts

1996 • 24 citations

Production of the transforming growth factor-β binding protein endoglin is regulated during chick heart development

1998 • 23 citations