Endoglin modulates cellular responses to TGF-beta 1.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

1994 • 1,452 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.

1992 • 837 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)

1993 • 755 citations

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

1991 • 661 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

The TGF-β family and its composite receptors

1994 • 539 citations

Transforming growth factor beta: the good, the bad, and the ugly.

1994 • 491 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.

1990 • 450 citations

Use of the polymerase chain reaction in the quantitation of MDR-1 gene expression

1990 • 427 citations

Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

1994 • 379 citations

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin.

1994 • 377 citations

Characterization and Cloning of a Receptor for BMP-2 and BMP-4 from NIH 3T3 Cells

1994 • 368 citations

Cloning and characterization of different human sequences related to the onc gene (v-myc) of avian myelocytomatosis virus (MC29).

1982 • 348 citations

A Transforming Growth Factor β Type I Receptor that Signals to Activate Gene Expression

1994 • 296 citations

TGF-β receptors and actions

1994 • 291 citations

Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line.

1988 • 256 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

Regulated expression on human macrophages of endoglin, an Arg‐Gly‐Asp‐containing surface antigen

1992 • 222 citations

VLA‐3: A novel polypeptide association within the VLA molecular complex: cell distribution and biochemical characterization

1986 • 214 citations

Identification and expression of two forms of the human transforming growth factor‐β‐binding protein endoglin with distinct cytoplasmic regions

1993 • 212 citations

Transforming growth factor beta enhances integrin expression and type IV collagenase secretion in human monocytes.

1993 • 211 citations

Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta.

1994 • 193 citations

Identification of distinct epitopes of endoglin, an RGD-containing glycoprotein of endothelial cells, leukemic cells, and syncytiotrophoblasts

1992 • 186 citations

The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand.

1993 • 181 citations

Receptors for Transforming Growth Factor-β

1993 • 181 citations

TGF-β Regulates Production of Growth Factors and TGF-β by Human Peripheral Blood Monocytes

1990 • 178 citations

Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells.

1994 • 133 citations

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

1995 • 131 citations

Transforming growth factor-beta potentiates vitamin D3-induced terminal monocytic differentiation of human leukemic cell lines.

1993 • 111 citations

Differential expression of endoglin on fetal and adult hematopoietic cells in human bone marrow.

1995 • 102 citations

Assignment of the human endoglin gene (END) to 9q34→qter

1993 • 95 citations

Endoglin is expressed on a subpopulation of immature erythroid cells of normal human bone marrow.

1991 • 92 citations

Molecular cloning and characterization of the human and porcine transforming growth factor-β type III receptors

1992 • 85 citations

Endoglin: a 180-kD endothelial cell and macrophage restricted differentiation molecule

1992 • 71 citations

Phosphorylation of the human-transforming-growth-factor-β-binding protein endoglin

1994 • 71 citations

Type I Receptors Specify Growth-Inhibitory and Transcriptional Responses to Transforming Growth Factor β and Activin

1994 • 70 citations

Signaling by the transforming growth factor-β receptor

1995 • 67 citations

Endoglin is a component of the transforming growth factor (TGF)-beta receptor complex of human pre-B leukemic cells.

1996 • 63 citations

Synergy between transforming growth factor-beta and tumor necrosis factor-alpha in the induction of monocytic differentiation of human leukemic cell lines

1990 • 62 citations

IFN-gamma and transforming growth factor-beta 1 differently regulate fibronectin and laminin receptors of human differentiating monocytic cells.

1992 • 62 citations

Characterization of a novel myeloid antigen regulated during differentiation of monocytic cells

1989 • 34 citations

Functional regulation of platelet/endothelial cell adhesion molecule-1 by TGF-beta 1 in promonocytic U-937 cells.

1994 • 33 citations

Regulation of Transforming Growth Factor a Gene Expression in an Ovarian Surface Epithelial Cell Line Derived from a Human Carcinoma1

1995 • 33 citations