CD105 antagonizes the inhibitory signaling of transforming growth factor βl on human vascular endothelial cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

1994 • 1,452 citations

Smad6 inhibits signalling by the TGF-β superfamily

1997 • 1,026 citations

Defective Angiogenesis in Mice Lacking Endoglin

1999 • 851 citations

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.

1992 • 837 citations

Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity

1997 • 715 citations

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1995 • 553 citations

Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

1990 • 470 citations

TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling

1997 • 470 citations

Angiogenesis and angiogenesis inhibition: An overview

1997 • 419 citations

Molecular and Cell Biology of TGF-β

1998 • 379 citations

Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

1994 • 379 citations

Breast carcinoma: vascular density determined using CD105 antibody correlates with tumor prognosis.

1999 • 340 citations

Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy.

1995 • 334 citations

Endoglin modulates cellular responses to TGF-beta 1.

1996 • 306 citations

Increased Expression of TGF-β1 in Brain Tissue After Ischemic Stroke in Humans

1996 • 275 citations

Role of Endoglin in Cellular Responses to Transforming Growth Factor-β

1998 • 223 citations

Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-beta.

1994 • 193 citations

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis.

1996 • 161 citations

Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies.

1999 • 140 citations

EDITORIAL. CD105 AND ANGIOGENESIS

1996 • 134 citations

TGF-?1 levels in pre-treatment plasma identify breast cancer patients at risk of developing post-radiotherapy fibrosis

1999 • 103 citations

Assignment of the human endoglin gene (END) to 9q34→qter

1993 • 95 citations

The response of endothelial cells to TGFβ-1 is dependent upon cell shape, proliferative state and the nature of the substratum

1991 • 83 citations

Increased Synovial Expression of Transforming Growth Factor (TGF)-β Receptor Endoglin and TGF-β1 in Rheumatoid Arthritis: Possible Interactions in the Pathogenesis of the Disease

1995 • 80 citations

TGF-beta receptors and signal transduction.

1997 • 76 citations

Phosphorylation of the human-transforming-growth-factor-β-binding protein endoglin

1994 • 71 citations

Irradiation induces Up‐regulation of E9 protein (CD105) in human vascular endothelial cells

1995 • 58 citations

Improved In Vitro Angiogenesis Model by Collagen Density Reduction and the Use of Type III Collagen

1993 • 46 citations

Upregulation of endoglin (CD105) expression during childhood brain tumor-related angiogenesis. Anti-angiogenic therapy.

1998 • 40 citations

Quantification of the repair process involved in the repair of a cell monolayer using an in vitro model of mechanical injury.

1998 • 39 citations

Inhibition of tubular morphogenesis in human microvascular endothelial cells by co-culture with chondrocytes and involvement of transforming growth factor β: a model for avascularity in human cartilage

1994 • 31 citations

Expression of endoglin in psoriatic involved and uninvolved skin

1995 • 28 citations

Inhibition of Endothelial Cell Growth by Macrophage-like U-937 Cell-derived Oncostatin M, Leukemia Inhibitory Factor, and Transforming Growth Factor β1

1996 • 26 citations

Role of transforming growth factor β3 in lymphatic metastasis in breast cancer

1998 • 26 citations

Role of transforming growth factor β3 in lymphatic metastasis in breast cancer

1998 • 22 citations

TGF-β Receptors and Signal Transduction

1996 • 16 citations

Opposing effects of heparin with TGF‐β or aFGF during repair of a mechanical wound of human endothelium. Influence of cAMP on cell migration

1992 • 14 citations

Glucosaminylmuramyl dipeptide (GMDP) modulates endothelial cell activities in vitro but has no effect on angiogenesis in vivo

1997 • 8 citations