Asymmetric Rab11 Endosomes Regulate Delta Recycling and Specify Cell Fate in the Drosophila Nervous System

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Rab proteins as membrane organizers

2001 • 3,320 citations

A monomeric red fluorescent protein

2002 • 2,344 citations

Rab11 regulates recycling through the pericentriolar recycling endosome.

1996 • 1,293 citations

Notch Signaling

1995 • 1,282 citations

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

1999 • 1,139 citations

Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro

2002 • 1,095 citations

Signal transduction and endocytosis: close encounters of many kinds

2002 • 820 citations

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1994 • 749 citations

Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch

1996 • 656 citations

Gradient Formation of the TGF-β Homolog Dpp

2000 • 606 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

2003 • 553 citations

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

2000 • 492 citations

Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes

1998 • 479 citations

Asymmetric Localization of a Mammalian Numb Homolog during Mouse Cortical Neurogenesis

1996 • 479 citations

Systematic gain-of-function genetics in Drosophila

1998 • 467 citations

Regulation of Notch Signaling Activity

2004 • 449 citations

Dare to Be Different: Asymmetric Cell Division in Drosophila, C. elegans and Vertebrates

2004 • 444 citations

Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release

2003 • 425 citations

Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells

2004 • 419 citations

Role of inscuteable in orienting asymmetric cell divisions in Drosophila

1996 • 389 citations

Development of adult sensilla on the wing and notum of Drosophila melanogaster

1989 • 383 citations

The Endocytic Protein α-Adaptin Is Required for Numb-Mediated Asymmetric Cell Division in Drosophila

2002 • 355 citations

Drosophila Neuralized Is a Ubiquitin Ligase that Promotes the Internalization and Degradation of Delta

2001 • 333 citations

Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

2002 • 323 citations

The Recycling Endosome of Madin-Darby Canine Kidney Cells Is a Mildly Acidic Compartment Rich in Raft Components

2000 • 319 citations

The FIP3-Rab11 Protein Complex Regulates Recycling Endosome Targeting to the Cleavage Furrow during Late Cytokinesis

2004 • 304 citations

Identification and Characterization of a Family of Rab11-interacting Proteins

2001 • 295 citations

Essential Roles of Drosophila RhoA in the Regulation of Neuroblast Proliferation and Dendritic but Not Axonal Morphogenesis

2000 • 291 citations

Sec15 Is an Effector for the Rab11 GTPase in Mammalian Cells

2004 • 280 citations

Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell

1999 • 264 citations

neuralized Encodes a Peripheral Membrane Protein Involved in Delta Signaling and Endocytosis

2001 • 258 citations

Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division

2000 • 249 citations

DrosophilaEpsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch

2004 • 246 citations

Unequal Segregation of Neuralized Biases Notch Activation during Asymmetric Cell Division

2003 • 236 citations

The Partner of Inscuteable/Discs-Large Complex Is Required to Establish Planar Polarity during Asymmetric Cell Division in Drosophila

2001 • 230 citations

Xenopus Neuralized Is a Ubiquitin Ligase that Interacts with XDelta1 and Regulates Notch Signaling

2001 • 225 citations

Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis

1997 • 207 citations

Partner of Numb Colocalizes with Numb during Mitosis and Directs Numb Asymmetric Localization in Drosophila Neural and Muscle Progenitors

1998 • 201 citations

Sec15, a Component of the Exocyst, Promotes Notch Signaling during the Asymmetric Division of Drosophila Sensory Organ Precursors

2005 • 200 citations

Trafficking through Rab11 Endosomes Is Required for Cellularization during Drosophila Embryogenesis

2003 • 192 citations

Asymmetric cell division during neurogenesis in Drosophila and vertebrates

2003 • 189 citations

Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

2003 • 186 citations

Rab11 polarization of theDrosophilaoocyte: a novel link between membrane trafficking, microtubule organization, andoskarmRNA localization and translation

2002 • 168 citations

Numb Inhibits Membrane Localization of Sanpodo, a Four-Pass Transmembrane Protein, to Promote Asymmetric Divisions in Drosophila

2003 • 161 citations

Arfophilins Are Dual Arf/Rab 11 Binding Proteins That Regulate Recycling Endosome Distribution and Are Related toDrosophilaNuclear Fallout

2003 • 132 citations

Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila

1999 • 128 citations

Cell polarity: the ups and downs of the Par6/aPKC complex

2003 • 116 citations

Identification of a Novel Rab11/25 Binding Domain Present in Eferin and Rip Proteins

2001 • 110 citations

Expression of rab11a N124I in gastric parietal cells inhibits stimulatory recruitment of the H⁺-K⁺-ATPase

1999 • 104 citations

A Gain-of-Function Screen for Genes That Affect the Development of the Drosophila Adult External Sensory Organ

2000 • 103 citations

Analysis of Notch1 Function by In Vitro T Cell Differentiation ofPax5Mutant Lymphoid Progenitors

2004 • 102 citations

Modes of Protein Movement that Lead to the Asymmetric Localization of Partner of Numb during Drosophila Neuroblast Division

1999 • 98 citations

Nuclear-fallout, a Drosophila protein that cycles from the cytoplasm to the centrosomes, regulates cortical microfilament organization

1998 • 86 citations

An Interaction Type of Genetic Screen Reveals a Role of the Rab11 Gene in oskar mRNA Localization in the Developing Drosophila melanogaster Oocyte

2001 • 82 citations

Formation of Mutually Exclusive Rab11 Complexes with Members of the Family of Rab11-interacting Proteins Regulates Rab11 Endocytic Targeting and Function

2002 • 81 citations

The Drosophila centrosomal protein Nuf is required for recruiting Dah, a membrane associated protein, to furrows in the early embryo

1999 • 54 citations

Modulation of developmental signals by endocytosis: different means and many ends

2003 • 54 citations

Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila

2001 • 47 citations

Imaginal disc silencers from Ultrabithorax: evidence for Polycomb response elements

1994 • 46 citations

Endocytic trafficking during Drosophila development

2003 • 37 citations

Lineage diversity in the Drosophila nervous system

2001 • 30 citations

Deleted Work

1955 • 0 citations