The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways

2000 • 832 citations

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

1994 • 749 citations

A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

2000 • 740 citations

Asymmetric segregation of Numb and Prospero during cell division

1995 • 489 citations

Drosophila Atypical Protein Kinase C Associates with Bazooka and Controls Polarity of Epithelia and Neuroblasts

2000 • 467 citations

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

1999 • 450 citations

Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity

2001 • 421 citations

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

2000 • 405 citations

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts

1999 • 375 citations

The PROSPERO transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila

1996 • 333 citations

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

2000 • 332 citations

A protein complex containing Inscuteable and the Gα-binding protein Pins orients asymmetric cell divisions in Drosophila

2000 • 332 citations

Asymmetric segregation of the homeodomain protein Prospero duringDrosophila development

1995 • 330 citations

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

2000 • 326 citations

Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions

1997 • 324 citations

Heterotrimeric G Proteins Direct Two Modes of Asymmetric Cell Division in the Drosophila Nervous System

2001 • 314 citations

Miranda Is Required for the Asymmetric Localization of Prospero during Mitosis in Drosophila

1997 • 284 citations

Cytoplasmic myosin from Drosophila melanogaster.

1986 • 256 citations

Control of spindle orientation in Drosophila by the Par-3-related PDZ-domain protein Bazooka

1998 • 233 citations

Yeast Homologues of Tomosyn and lethal giant larvae Function in Exocytosis and Are Associated with the Plasma Membrane Snare, Sec9

1999 • 216 citations

Partner of Numb Colocalizes with Numb during Mitosis and Directs Numb Asymmetric Localization in Drosophila Neural and Muscle Progenitors

1998 • 201 citations

Mammalian Homolog of Drosophila Tumor Suppressor Lethal (2) Giant Larvae Interacts with Basolateral Exocytic Machinery in Madin-Darby Canine Kidney Cells

2002 • 183 citations

The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain.

1994 • 171 citations

Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster

2002 • 167 citations

The Drosophila lethal(2)giant larvae tumor suppressor protein is a component of the cytoskeleton.

1994 • 134 citations

A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.

1995 • 83 citations

Sro7p, a Saccharomyces cerevisiae Counterpart of the Tumor Suppressor l(2)gl Protein, Is Related to Myosins in Function

1998 • 67 citations

A serine-kinase associated with the p127-l(2)gl tumour suppressor of Drosophila may regulate the binding of p127 to nonmuscle myosin II heavy chain and the attachment of p127 to the plasma membrane

1996 • 61 citations

Drosophila syntaxin Is Required for Cell Viability and May Function in Membrane Formation and Stabilization

1996 • 59 citations