Loss of HLA molecules in B lymphomas is associated with an aggressive clinical course

A Predictive Model for Aggressive Non-Hodgkin's Lymphoma

1993 • 4,650 citations

A predictive model for aggressive non-Hodgkin's lymphoma

1993 • 3,483 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

A Critical Role for Tapasin in the Assembly and Function of Multimeric MHC Class I-TAP Complexes

1997 • 528 citations

Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinial relevance

1995 • 478 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

Natural history of HLA expression during tumour development

1993 • 448 citations

NK susceptibility varies inversely with target cell class I HLA antigen expression.

1987 • 433 citations

Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals

1995 • 426 citations

A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4.

1994 • 365 citations

Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas.

1994 • 333 citations

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1995 • 320 citations

Control of programmed cell death in normal and leukemic cells: new implications for therapy

1993 • 297 citations

HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in Western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy

1990 • 252 citations

Natural Killer Cells: From No Receptors to Too Many

1997 • 236 citations

Site α Is Crucial for Two Routes of IFNγ-Induced MHC Class I Transactivation: The ISRE-Mediated Route and a Novel Pathway Involving CIITA

1997 • 217 citations

Induction of MHC Class I Expression by the MHC Class II Transactivator CIITA

1997 • 209 citations

A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer

1996 • 196 citations

Loss of antigen-presenting molecules (MHC class I and TAP-1) in lung cancer

1996 • 186 citations

The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1.

1997 • 159 citations

Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors.

1994 • 143 citations

High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas

1998 • 143 citations

CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.

1997 • 140 citations

Human Histocompatibility Leukocyte Antigen (HLA)-G Molecules Inhibit NKAT3 Expressing Natural Killer Cells

1997 • 139 citations

High frequency of altered HLA class I phenotypes in invasive breast carcinomas

1996 • 120 citations

Lymphocyte programmed cell death is mediated via HLA class II DR

1994 • 111 citations

Autologous Tumor Infiltrating T Cells Cytotoxic for Follicular Lymphoma Cells Can Be Expanded In Vitro

1997 • 102 citations

HLA-DR (Ia) immune phenotype predicts outcome for patients with diffuse large cell lymphoma.

1988 • 99 citations

HLA‐G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex

1997 • 90 citations

Defective expression of MHC class I antigens is frequent in B‐cell lymphomas of high‐grade malignancy

1987 • 88 citations

Anti-human class I MHC antibodies induce apoptosis by a pathway that is distinct from the Fas antigen-mediated pathway.

1997 • 80 citations

Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma

1996 • 80 citations

MHC class I ligation of human T cells activates the ZAP70 and p56lck tyrosine kinases, leads to an alternative phenotype of the TCR/CD3 zeta-chain, and induces apoptosis.

1997 • 78 citations

HLA Class II–Mediated Death Is Induced Via Fas/Fas Ligand Interactions in Human Splenic B Lymphocytes

1997 • 74 citations

Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes

1995 • 73 citations

B‐cell lymphomas of high‐grade malignancy frequently lack HLA‐DR, ‐DP and ‐DQ antigens and associated invariant chain

1987 • 66 citations

The effect of class II gene transfection on the tumourigenicity of the H-2K-negative mouse leukaemia cell line K36.16.

1991 • 46 citations

Are transporter associated with antigen processing (TAP) and tapasin class I MHC chaperones?

1997 • 42 citations

Ligation of HLA class II molecules promotes sensitivity to CD95 (Fas antigen, APO‐1)‐mediated apoptosis

1995 • 38 citations

Deficient expression of class-I HLA in some cases of acute leukemia

1984 • 25 citations

DISTRIBUTION OF HLA‐G ALTERNATIVE mRNAs INCLUDING SOLUBLE FORMS IN NORMAL LYMPHOCYTES AND IN LYMPHOID CELL‐DERIVED LEUKEMIA

1996 • 22 citations

Altered expression of histocompatibility antigens on "B" large cell lymphomas

1981 • 15 citations

Autologous Tumor Infiltrating T Cells Cytotoxic for Follicular Lymphoma Cells Can Be Expanded In Vitro

1997 • 12 citations

Major histocompatibility complex class I and class II antigen expression in diffuse large cell and large cell immunoblastic lymphomas. Absence of a correlation between antigen expression and clinical outcome.

1993 • 11 citations

Loss of surface HLA class I molecules in leukemic myeloblasts is correlated with an increased leukocyte concentration at onset.

1992 • 9 citations

QUANTITATIVE EXPRESSION OF HLA CLASS I MOLECULES IN ACUTE NON‐LYMPHOBLASTIC LEUKAEMIA CELLS

1993 • 3 citations