Heat Shock Enhances the Susceptibility of Tumor Cells to Lysis by Lymphokine-Activated Killer Cells

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

Heat shock, stress proteins, chaperones, and proteotoxicity

1991 • 1,069 citations

Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein

1990 • 1,035 citations

Proteins as molecular chaperones

1987 • 910 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

Stress proteins, infection, and immune surveillance

1989 • 477 citations

Tumor rejection antigens of chemically induced sarcomas of inbred mice.

1986 • 463 citations

Unusual expression and localization of heat‐shock proteins in human tumor cells

1992 • 439 citations

Human γδ+ T cells respond to mycobacterial heat-shock protein

1989 • 417 citations

Human major histocompatibility complex contains genes for the major heat shock protein HSP70.

1989 • 336 citations

Lymphokine-activated killer cells: lysis of fresh syngeneic natural killer-resistant murine tumor cells by lymphocytes cultured in interleukin 2.

1984 • 299 citations

Leu-11+ lymphocytes with natural killer (NK) activity are precursors of recombinant interleukin 2 (rIL 2)-induced activated killer (AK) cells.

1985 • 263 citations

Current results of conservative surgery for differentiated thyroid carcinoma

1986 • 189 citations

Rapid assay for evaluating the chemosensitivity of human tumors in soft agar culture.

1982 • 124 citations

Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes.

1985 • 95 citations

Intrapleural administration of OK432 in cancer patients: Activation of nk cells and reduction of suppressor cells

1983 • 95 citations

Selective lysis of the autologous tumor by δTCS1⁺ γ/δ⁺ tumor‐infiltrating lymphocytes from human lung carcinomas

1990 • 87 citations

Mortality from papillary thyroid carcinoma: A case-control study of 56 lethal cases

1988 • 80 citations

Heat shock protects WEHI‐164 target cells from the cytolysis by tumor necrosis factors α and β

1989 • 80 citations

Modified neck dissection in treatment of thyroid cancer: A safe procedure

1988 • 66 citations

Modified neck dissection for patients with nonadvanced, differentiated carcinoma of the thyroid

1988 • 51 citations

Elevated temperature regulates tumor necrosis factor‐mediated immune killing

1989 • 50 citations

Recruitment of T lymphocytes and induction of tumor necrosis factor in thyroid cancer by a local immunotherapy

1992 • 45 citations

Effects of stress on lysability of tumor targets by cytotoxic T cells and tumor necrosis factor.

1990 • 43 citations

External irradiation for malignant thyroid tumors.

1980 • 30 citations

Effect of tunicamycin on sialomucin and natural killer susceptibility of rat mammary tumor ascites cells.

1990 • 26 citations

Suppression of human natural killer cell activity by amino sugars

1989 • 22 citations

Effect of heat treatment on tumor cells and antitumor effector cells.

1990 • 22 citations

Papillary carcinoma of the thyroid gland.

1985 • 20 citations

Interstitial thermal radiation therapy: five-year experience with head and neck tumors.

1992 • 17 citations

Simultaneous Radiotherapy and Chemotherapy with Carboplatin in Inoperable Squamous Cell Carcinoma of the Head and Neck: A Phase II Study

1992 • 17 citations

Swainsonine Augments the Cytotoxicity of Human Lymphokine-Activated Killer Cells Against Autologous Thyroid Cancer Cells

1994 • 16 citations

Primary advanced and local recurrent head and neck tumors: effective management with interstitial thermal radiation therapy.

1990 • 16 citations

Effects of interleukin 2 treatment combined with local hyperthermia in mice inoculated with Lewis lung carcinoma cells.

1990 • 15 citations

Responses of killer cells in head and neck cancer patients

1990 • 10 citations

Interstitial thermoradiotherapy for recurrent head and neck cancer

1989 • 8 citations

Immunohistochemical studies on local antitumor effects of streptococcal immunopotentiator, OK-432, in human solid malignant tumors.

1988 • 6 citations

Lymphokine-activated Killer (LAK) Activity Against Autologous Malignant Tumors of the Skin

1988 • 5 citations

Tumor-specific lysis by long-term cultured tumor-infiltrating lymphocytes

1987 • 4 citations