Regulation of p53 activity through lysine methylation

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Translating the Histone Code

2001 • 9,488 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2

1997 • 2,089 citations

Post‐translational modifications and activation of p53 by genotoxic stresses

2001 • 1,076 citations

SET Domain-containing Protein, G9a, Is a Novel Lysine-preferring Mammalian Histone Methyltransferase with Hyperactivity and Specific Selectivity to Lysines 9 and 27 of Histone H3

2001 • 761 citations

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

2003 • 735 citations

Acetylation of p53 Activates Transcription through Recruitment of Coactivators/Histone Acetyltransferases

2001 • 704 citations

MDM2 — master regulator of the p53 tumor suppressor protein

2000 • 637 citations

SUMO-1 modification activates the transcriptional response of p53

1999 • 627 citations

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

2002 • 555 citations

Purification and Functional Characterization of a Histone H3-Lysine 4-Specific Methyltransferase

2001 • 511 citations

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1

1999 • 507 citations

Acetylation of p53 Inhibits Its Ubiquitination by Mdm2

2002 • 478 citations

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

2004 • 406 citations

Structure and catalytic mechanism of the human histone methyltransferase SET7/9

2003 • 369 citations

Gene-Specific Modulation of TAF10 Function by SET9-Mediated Methylation

2004 • 242 citations

Data collection and processing

2013 • 199 citations

Functional analysis and intracellular localization of p53 modified by SUMO-1

2001 • 131 citations

Dynamics of the p53 Acetylation Pathway

2004 • 58 citations

The High Levels of p53 Present in Adenovirus Early Region 1-Transformed Human Cells do Not Cause Up-Regulation of MDM2 Expression

1995 • 29 citations