Tumor hypoxia: its impact on cancer therapy

Statistical Method in Biological Assay.

1979 • 3,679 citations

The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy

1955 • 2,174 citations

The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in Radiotherapy

1953 • 2,102 citations

Statistical Method in Biological Assay.

1966 • 820 citations

Radiation Biology in Cancer Research

1980 • 782 citations

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

1968 • 764 citations

Growth Kinetics of Tumours

1978 • 691 citations

The radiobiology of cultured mammalian cells

1967 • 687 citations

II. Clinical Application

1957 • 615 citations

Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data

1984 • 610 citations

Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells.

1981 • 552 citations

Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation

1979 • 523 citations

A critique of the evidence for active host defence against cancer, based on personal studies of 27 murine tumours of spontaneous origin

1976 • 478 citations

Definitive evidence for hypoxic cells influencing cure in cancer therapy.

1978 • 422 citations

Characteristics of a Serially Transplanted Mouse Mammary Tumor and Its Tissue-Culture-Adapted Derivative

1972 • 411 citations

Radiation and High-Dose Metronidazole in Supratentorial Glioblastomas

1976 • 309 citations

A marker for hypoxic cells in tumours with potential clinical applicability

1981 • 309 citations

The Phenomenon of Reoxygenation and Its Implications for Fractionated Radiotherapy

1972 • 296 citations

The hypoxic tumor cell: A target for selective cancer chemotherapy

1980 • 291 citations

Changes of cell proliferation characteristics in a rat rhabdomyosarcoma before and after X-irradiation

1969 • 274 citations

Oxygen diffusion and the distribution of cellular radiosensitivity in tumours

1972 • 267 citations

Experimental radiotherapy of a rat rhabdomyosarcoma with 15 MeV neutrons and 300 kV X-rays

1970 • 260 citations

Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.

1970 • 243 citations

Primary radiotherapy of larynx and pharynx carcinoma—An analysis of some factors influencing local control and survival

1986 • 241 citations

The Sensitivity of Microorganisms to Irradiation under Controlled Gas Conditions

1957 • 225 citations

A Multicomponent X-ray Survival Curve for Mouse Lymphosarcoma Cells irradiated in vivo

1963 • 224 citations

Quantitative measurements of oxygen tension in normal tissues and in the tumours of patients before and after radiotherapy

1960 • 222 citations

Statistical Theory and Methodology in Science and Engineering.

1966 • 221 citations

A Survival Curve for Mammalian Leukaemia Cells Irradiated 'in vivo (Implications for the Treatment of Mouse Leukaemia by Whole-Body Irradiation)

1959 • 218 citations

Proliferation-dependent cytotoxicity of anticancer agents: a review.

1975 • 216 citations

Oxygenation status of a transplantable tumor during fractionated radiation therapy.

1968 • 213 citations

Perfluorochemical Emulsions Can Increase Tumor Radiosensitivity

1984 • 209 citations

Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental and Human Tumors

2020 • 202 citations

Repair of Potentially Lethal Radiation DamageIn VitroandIn Vivo

1973 • 194 citations

31P NMR spectroscopy of in vivo tumors

1982 • 190 citations

On the Access of Blood-Borne Dyes to Various Tumour Regions

1962 • 187 citations

An estimation of changes in the proportions and absolute numbers of hypoxic cells after irradiation of transplanted C₃H mouse mammary tumours

1969 • 183 citations

Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.

1984 • 178 citations

Chemical sensitizers for hypoxic cells: A decade of experience in clinical radiotherapy

1985 • 177 citations

Hypoxia in neoplastic tissue

1977 • 176 citations

The gross response of an experimental tumour to single doses of x-rays.

1967 • 172 citations

³¹P Nuclear Magnetic Resonance Spectroscopic Investigation of Human Neuroblastoma in Situ

1985 • 168 citations

Rodent tumor models in experimental cancer therapy

1988 • 165 citations

Cancer a Comprehensive Treatise 2

1975 • 160 citations

Hyperbaric oxygen: the Medical Research Council trials and their clinical significance

1978 • 157 citations

Binding of 3H-misonidazole to solid human tumors as a measure of tumor hypoxia

1986 • 155 citations

Cellular Radiosensitivity and Tumor Radiation Response in the EMT6 Tumor Cell System

1973 • 149 citations

The Choice of Animal Tumors for Experimental Studies of Cancer Therapy

1978 • 143 citations

Vascular occlusion and tumour cell death

1983 • 142 citations

Radiobiologic basis of oxygen as a modifying factor in radiation therapy.

1961 • 141 citations

A Factor of Importance in the Radio Sensitivity of Tumours

1936 • 140 citations

Intracapillary oxyhemoglobin saturation of malignant tumors in humans

1981 • 131 citations

The kinetics of tumour cell proliferation and radiotherapy

1971 • 130 citations

Influence of hypoxia and an acidic environment on the metabolism and viability of cultured cells: potential implications for cell death in tumors.

1986 • 130 citations

Development of Target-Oriented Anticancer Drugs

1984 • 122 citations

The effect of oxygen on cellular survival and recovery after radiation

1969 • 121 citations

The effect of anaemia on the fraction of hypoxic cells in an experimental tumour

1971 • 119 citations

The detection and measurement of hypoxic cells in solid tumors

1984 • 117 citations

The action of radium on cancer cells. II.—Some factors determining the susceptibility of cancer cells to radium

1933 • 117 citations

The Effect of Tissue Oxygen Tension on the Radiosensitivity of Leukaemia Cells Irradiated In Situ in the Livers of Leukaemic Mice

1959 • 115 citations

ESR studies of O2 uptake by Chinese hamster ovary cells during the cell cycle.

1982 • 115 citations

Tests of Two Electron-Affinic Radiosensitizers in Vivo Using Regrowth of an Experimental Carcinoma

1975 • 115 citations

Response of Chinese hamster ovary cells to anticancer drugs under aerobic and hypoxic conditions

1981 • 110 citations

Use of a perfluorochemical emulsion to improve oxygenation in a solid tumor

1985 • 110 citations

Biophysical Aspects of Radiation Quality

1968 • 102 citations

Oxygen tension in human tumors: in vivo mapping using CT-guided probes.

1985 • 102 citations

The effect of hypoxia on the growth and radiation response of mammalian cells in culture

1974 • 101 citations

Quantitative evaluation of the radiosensitivity of cells of a transplantable rhabdomyosarcoma in the rat

1966 • 99 citations

The Effect of Oxygen Breathing and Radiotherapy upon the Tissue Oxygen Tension of some Human Tumours

1963 • 99 citations

Influence of tumour size on hypoxic fraction and therapeutic sensitivity of Lewis lung tumour

1977 • 95 citations

Biological Bases and Clinical Implications of Tumor Radioresistance

1980 • 91 citations

The Inactivation of Chinese Hamster Cells by X Rays: Synchronized and Exponential Cell Populations

1975 • 91 citations

Carbogen breathing during radiation therapy The radiation therapy oncology group study

1979 • 90 citations

The statistics of dose/cure relationships for irradiated tumours. Part II

1980 • 90 citations

Demonstration of radiosensitization of hypoxic cells in solid tumours by metronidazole

1974 • 90 citations

The statistics of dose/cure relationships for irradiated tumours. Part I.

1980 • 89 citations

Dependence of response of a C3H mammary carcinoma to fractionated irradiation on fractionation number and intertreatment interval.

1977 • 87 citations

Tumor size dependency in the radiation response of the Lewis lung carcinoma.

1975 • 86 citations

Effect of Heat and Ionizing Radiation on Normal and Neoplastic Tissue of the C3H Mouse

1975 • 86 citations

Repair of radiation damage in Lewis lung carcinoma cells following in situ treatment with fast neutrons and gamma-rays.

1975 • 86 citations

The Steepness of the Dose—Response Curve in Radiation Therapy

1975 • 84 citations

The response of hypoxic B16 melanoma cells to in vivo treatment with chemotherapeutic agents.

1975 • 82 citations

Misonidazole and other hypoxia markers: Metabolism and applications

1986 • 81 citations

Response to the RIF-1 tumor in vitro and in C3H/Km mice to X-radiation (cell survival, regrowth delay, and tumor control), chemotherapeutic agents, and activated macrophages.

1980 • 81 citations

Cell cycle distribution of chronically hypoxic cells and determination of the clonogenic potential of cells accumulated in G2 + M phases after irradiation of a solid tumor in vivo.

1979 • 81 citations

Correlations between 31 P NMR Spectroscopy and 15 O Perfusion Measurements in the RIF-1 Murine Tumor in Vivo

1986 • 80 citations

The labelling of EMT-6 tumours in BALB/C mice with¹⁴C-misonidazole

1983 • 80 citations

Covalent binding of a fluorinated 2-nitroimidazole to emt-6 tumors in Balb/C mice: detection by f-19 nuclear magnetic resonance at 2.35 T

1986 • 78 citations

Repair of Potentially Lethal Radiation Damage in Acute and Chronically Hypoxic Tumor Cellsin Vivo

1976 • 77 citations

Dependence of Response of a C3H Mammary Carcinoma to Fractionated Irradiation on Fractionation Number and Intertreatment Interval

1977 • 76 citations

On the nature of the radiobiologically hypoxic fraction in tumors

1980 • 75 citations

A clinical trial of Fluosol DA 20% in advanced squamous cell carcinoma of the head and neck

1986 • 75 citations

Cellular radiosensitivity of a rat brain tumor

1975 • 74 citations

In vivotesting of hypoxic radiosensitizers using the KHT murine tumour assayed by the lung-colony technique

1975 • 73 citations

Tumors of Bone and Soft Tissue.

1965 • 73 citations

The growth of transplanted murine tumours in pre-irradiated sites

1968 • 73 citations

Plateau Phase in Growth Induced by Hypoxia

1973 • 70 citations

The relative effects of fast neutrons and X rays on tumour and normal tissue in the rat. Part II. Fractionation: recovery and reoxygenation

1968 • 70 citations

The effect of radiation on tumour growth delay, cell survival and cure of the animal using a single tumour system

1977 • 68 citations

Radiosensitivity of Four Human Tumor Xenografts. Influence of Hypoxia and Cell-Cell Contact

1983 • 68 citations

A Rapid Method for studying Tumour Blood Supply using Systemic Dyes

1959 • 68 citations

On the Alteration in the Sensitivity of Cells Towards Radiation Produced by Cold and by Anærobiosis

1935 • 67 citations

Survival Curve of a Human Melanoma in Nude Mice

1977 • 66 citations

Is tumour radiosensitization by misonidazole a general phenomenon?

1980 • 64 citations

Demonstration of an Anoxic Component in a Mouse Tumor-Cell Population by in Vivo Assay of Survival Following Irradiation

1964 • 64 citations

The Effect of Oxygen on the Response of Spontaneous Tumours in Mice to Radiotherapy

1963 • 63 citations

Human tumors as examined by in vivo 31P NMR in athymic mice

1982 • 63 citations

Evidence for an Unconventional Radiosensitivity of Rat 9L Subcutaneous Tumors

1980 • 63 citations

In vitro and in vivo radiosensitivity of human tumour cells obtained from a pancreatic carcinoma xenograft

1976 • 62 citations

The effect of prolonged hypoxia on growth and viability of Chinese hamster cells

1976 • 62 citations

Dose-response curve and split-dose recovery in human skin cancer

1984 • 62 citations

Tumour cords in 52 human bronchial and cervical squamous cell carcinomas: Inferences for their cellular kinetics and radiobiology

1985 • 61 citations

Fluorescent nitroheterocycles for identifying hypoxic cells.

1983 • 60 citations

Biological Basis for High-LET Radiotherapy

1973 • 59 citations

La Ronde—radiation sciences and medical radiology

1983 • 58 citations

Radiation Response of the Cells of a Human Malignant Melanoma Xenograft. Effect of Hypoxic Cell Radiosensitizers

1981 • 57 citations

The radiosensitivity of a murine fibrosarcoma as measured by three cell survival assays.

1980 • 56 citations

The effect of single and fractionated doses of X rays on the effective proportion of hypoxic cells in C₃H mouse mammary tumours

1972 • 56 citations

The Proliferative Status And Clonogenic Capacity Of Tumour Cells In A Transplantable Rhabdomyosarcoma Of The Rat Before And After Irradiation With 800 Rad Of X‐Rays

1978 • 55 citations

Cell killing, radiosensitization and cell cycle redistribution induced by chronic hypoxia

1984 • 53 citations

Repair of Sublethal Radiation Injury in Hypoxic Cells of a C 3 H Mouse Mammary Carcinoma

1969 • 53 citations

In vivo-in vitro tumour cell lines: characteristics and limitations as models for human cancer.

1980 • 52 citations

The Effect of Hypoxia on the Generation Time of Mammalian Cells

1973 • 51 citations

Reoxygenation in the RIF-1 tumor

1984 • 50 citations

Changes in misonidazole binding with hypoxic fraction in mouse tumors

1985 • 50 citations

Oxygenation in radiotherapy.

1959 • 49 citations

Oxygenation of malignant tumors after localized microwave hyperthermia

1982 • 49 citations

The Radiation Sensitivities of R3327-H and R3327-AT Rat Prostate Adenocarcinomas

1985 • 49 citations

Intracapillary HbO2 saturation in malignant tumors during normoxia and hyperoxia

1979 • 48 citations

OXYGEN EFFECT FACTOR AND TUMOR VOLUME IN THE C₃H MOUSE MAMMARY CARCINOMA

1966 • 48 citations

Tumour oxygenation under normobaric and hyperbaric conditions

1983 • 46 citations

The Effect of Pentobarbital Anaesthesia on the Radiosensitivity of Four Mouse Tumours

1979 • 46 citations

The Effect of Extreme Hypoxia and Glucose on the Repair of Potentially Lethal and Sublethal Radiation Damage by Mammalian Cells

1977 • 45 citations

Oxygenation and reoxygenation in 'sandwich' tumours.

1977 • 45 citations

The Effect of Hypoxia on the Repair of Sublethal Radiation Damage in Cultured Mammalian Cells

1972 • 44 citations

Effects of extreme hypoxia on the growth and viability of EMT6/SF mouse tumor cells in vitro.

1983 • 44 citations

A comparison of the effects of radiation on tumour growth delay and cell survival (The effect of oxygen)

1973 • 44 citations

Radioprotection by Pentobarbitone Sodium of a Murine Tumourin Vivo

1977 • 43 citations

Binding of misonidazole to V79 spheroids and fragments of dunning rat prostatic and human colon carcinomas in vitro: Diffusion of oxygen and reactive metabolites

1984 • 42 citations

Quantitative Radiosensitivity Studies of Solid Carcinomas <italic>In Vivo</italic>: Methodology and Effect of Anoxia<xref ref-type="fn" rid="FN1">2</xref>

1966 • 42 citations

EXPLOITATION OF THE OXYGEN ENHANCEMENT RATIO IN CLINICAL PRACTICE

1973 • 41 citations

Cell Cycle Kinetics of Aerated, Hypoxic and Re‐Aerated Cells In Vitro Using Flow Cytometric Determination of Cellular Dna and Incorporated Bromodeoxyuridine

1985 • 41 citations

Human tumour xenografts: a critical appraisal.

1980 • 40 citations

Effect of hyperthermia on the hypoxic fraction in an experimental mammary carcinomain vivo

1981 • 40 citations

Inhibition of cell-cycle progression by acute treatment with various degrees of hypoxia: Modifications induced by low concentrations of misonidazole present during hypoxia

1983 • 40 citations

A New Method of Determining the Fraction of Hypoxic Cells in a Transplantable Murine Sarcoma

1977 • 39 citations

Effect of Induced Host Anaemia on the Viability and Radiosensitivity of Murine Malignant Cells in vivo

1971 • 39 citations

Measurement of Mammary Tumor Blood Flow in Unanesthetized Rats2

1978 • 39 citations

Will hyperthermia conquer the elusive hypoxic cell? Implications of heat effects on tumor and normal-tissue microcirculation.

1980 • 38 citations

Response of Anoxic C3H Mouse Mammary Carcinoma Isotransplants (1–25 mm<sup>3</sup>) to X Irradiation<xref ref-type="fn" rid="FN2">2</xref>

1963 • 37 citations

The response of C₃H mammary tumours to Irradiation in single and fractionated doses

1968 • 37 citations

The effect of tumor size and host anemia on tumor cell survival after irradiation

1978 • 37 citations

Reoxygenation of tumours in “sandwich” chambers

1979 • 36 citations

Is cell survival a determinant of the in situ response of 9L tumours?

1980 • 35 citations

Human tumour xenografts in radiotherapeutic research

1985 • 35 citations

Cell Proliferation In Emt6 Tumors Treated With Single Doses of X‐Rays Or Hydroxyurea. I. Experimental Results

1978 • 35 citations

Effect of duration of breathing 95% oxygen plus 5% carbon dioxide before X-irradiation on cure of C3H mammary tumor

1970 • 34 citations

Thein VitroSensitivity of Chronically Hypoxic EMT6/SF Cells to X-radiation and Hypoxic Cell Radiosensitizers

1985 • 34 citations

Radiation Response of Cell Populations Irradiated in Situ and Separated from a Fibrosarcoma

1976 • 34 citations

Evidence for repair capacity in mouse tumors relative to skin

1979 • 34 citations

Hypoxic Fraction and Repair of Potentially Lethal Radiation Damage in Two Human Melanomas Transplanted into Nude Mice

1981 • 33 citations

Kryomicrophotometry as a Method for Analyzing the Intracapillary HbO2 Saturation of Organs Under Different O2 Supply Conditions

1976 • 33 citations

Effect of tumor blood flow manipulations on radiation response

1983 • 33 citations

Split dose recovery of a mouse tumour and its stroma during fractionated irradiation

1982 • 32 citations

Biological Properties and Response to X-rays of First-generation Transplants of Spontaneous Mammary Carcinomas in C3H Mice

1975 • 32 citations

In Vivo Cell Survival and Volume Response Characteristics of Rat Rhabdomyosarcoma Tumors Irradiated in the Extended Peak Region of Carbon- and Neon-Ion Beams

1980 • 32 citations

Effects of Sodium Pentobarbital on the Radiation Response of EMT6 Cells in Vitro and EMT6 Tumors in Vivo

1980 • 32 citations

The Response of Viable Tumor Cords to a Single Dose of Radiation

1973 • 31 citations

Deoxycytidylate shortage is a cause of G1 arrest of ascites tumor cells under oxygen deficiency

1983 • 30 citations

Hypoxic Fraction Determinations with the BA1112 Rat Sarcoma: Variation within and among Assay Techniques

1984 • 30 citations

Modification of tumor response to cyclophosphamide and irradiation by preirradiation of the tumor bed: Prolonged growth delay but reduced curability

1985 • 29 citations

Modification of radiation response

1984 • 29 citations

The oxygen effect and radiotherapy with fast neutrons

1971 • 29 citations

An appraisal of in vivo assays of excised tumours.

1980 • 28 citations

Effects of Radiation on Animal Tumor Models

1977 • 28 citations

Advances in radiation research : biology and medicine

1973 • 28 citations

Cellular and Molecular Repair of X-Ray-Induced Damage: Dependence on Oxygen Tension and Nutritional Status

1985 • 28 citations

Modification of the radiocurability of a syngeneic murine squamous carcinoma by its site of growth, by electron-affinic drugs, and by ICRF 159

1976 • 27 citations

Combinations of Radiation and Misonidazole in a Murine Lung Tumor Model

1981 • 27 citations

The Change in Hypoxic and Chronically Hypoxic Cell Fraction in Murine Tumors Treated with Hyperthermia

1983 • 27 citations

Response of EMT-6 Tumors to Single Fractions of X Rays and Cyclotron Neutrons: Evaluation and Comparison of Multiple Endpoints

1977 • 26 citations

Towards a further understanding of the growth-inhibiting action of oxygen deficiency

1985 • 25 citations

The Effect of Anesthetics on the Radiosensitivity of a Murine Tumor

1979 • 25 citations

Reoxygenation of the RIF-1 tumor after fractionated radiotherapy

1986 • 25 citations

Bromomisonidazole: Synthesis and Characterization of a New Radiosensitizer

1982 • 24 citations

Further investigations of the effects of the hypoxic-cell radiosensitizer, Ro-07-0582, on local control of a mouse tumour

1977 • 24 citations

Radiation response of two human malignant melanomas grown in athymic nude mice

1981 • 23 citations

Comparative chemosensitivity of exponential- versus plateau-phase cells in both in vitro model systems.

1976 • 23 citations

Kinetic heterogeneity in density-separated murine fibrosarcoma subpopulations.

1982 • 23 citations

Tumor-to-tumor variability in the hypoxic fractions of experimental rodent tumors

1984 • 23 citations

In vitro hypoxic cytotoxicity of nitroimidazoles: Uptake and cell cycle phase specificity

1982 • 22 citations

A Rapid Method for studying Tumour Blood Supply using Lissamine Green

1960 • 22 citations

Experimental chemotherapy studies: intercomparison of assays.

1980 • 22 citations

Regional variation in the oxygenation of mouse mammary tumoursin vivodemonstrated by fluorescence of pyridine nucleotide

1972 • 22 citations

“Oxygen Effect” and Tumor Size as Related to Response of C3H/Ba Adenocarcinoma to Local X Irradiation

1960 • 21 citations

RADIATION DOSE FRACTIONATION AND HIGH PRESSURE OXYGEN IN RADIOTHERAPY OF THE DBA MOUSE MAMMARY CARCINOMA

1967 • 21 citations

Cell Survival in Rat Rhabdomyosarcoma Tumors Irradiated in Vivo with Extended-Peak Silicon Ions

1982 • 20 citations

Recovery from sublethal damage by acutely hypoxic tumour cellsin vivoandin vitro

1979 • 20 citations

The recovery of the survival curve shoulder after protracted hypoxia

1971 • 20 citations

Preliminary results of bladder carcinoma irradiated with low individual doses and a high total dose

1976 • 20 citations

Nitroakridin 3582: a fluorescent nitroacridine stain for identifying hypoxic cells

1983 • 19 citations

Oxygen washout studies in the anesthetized dog

1963 • 19 citations

A Change in the Oxygen Effect Throughout the Cell-cycle of Human Cells of the Line NHIK 3025 Cultivatedin Vitro

1977 • 18 citations

Influence of tumour size on radiosensitization by misonidazole.

1978 • 18 citations

Effectiveness and biological effects of techniques used to induce hypoxia in solid tumors

1986 • 18 citations

A comparison of the effects of radiation on tumour growth delay and cell survival. The effect of radiation quality

1975 • 18 citations

Tumour size: a factor influencing the isoeffect analysis of tumour response to combined modalities.

1980 • 18 citations

Radiobiological studies of tumours in situ compared with cell survival.

1980 • 18 citations

Comparison between the Binding of [ 3 H]Misonidazole and AF-2 in Chinese Hamster V79 Spheroids

1986 • 17 citations

Assessment of tumour response in a rat rhabdomyosarcoma.

1980 • 16 citations

Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus

1980 • 15 citations

Influence ofin vitroassay conditions on the assessment of radiobiological parameters of the MT tumour

1980 • 15 citations

A Low Oxygen-enhancement Ratio for Tumour-cell Survival as Compared with that for Tumour-growth Delay

1972 • 14 citations

Monitored Regional Hypoxia in Radiotherapy

1966 • 14 citations

Tumour response endpoints in the BA1112 rat sarcoma.

1980 • 14 citations

Stromal radiosensitivity: influence of tumour type on the Tumour Bed Effect assay

1985 • 13 citations

Radiosensitivity of Lymph Node Metastases versus Initial Subcutaneous Tumors in Nude Mice

1979 • 13 citations

Thein VitroSensitivities to Radiation and Misonidazole of Mouse Bone Marrow Cells Derived from Different Microenvironments

1985 • 12 citations

Alterations in the DNA metabolism of MCa-11 mouse mammary tumor cells grown in vivo and in vitro.

1986 • 12 citations

Unconventional fractionation in clinical radiotherapy.

1978 • 11 citations

Effects of irradiation by single or multiple fractions per day on a transplantable murine mammary carcinoma

1982 • 11 citations

Experimental radiation therapy and apparent radioresistance of autochthonous tumors subcutaneously induced with 3-methylcholanthrene in mice.

1980 • 11 citations

Oxygen and nitroreductase-dependent binding of af-2 in spheroids and murine tumors

1986 • 10 citations

Hypoxia mediated binding of misonidazole in non-malignant tissue

1986 • 8 citations

Comparison of the effects of neutron and/or photon irradiation on spontaneous squamous-cell carcinoma in mice.

1980 • 7 citations

Cell-cycle distributions and radiation responses of Chinese hamster cells cultured continuously under hypoxic conditions

1984 • 6 citations

A low frequency imaging electron spin resonance spectrometer for non-invasive measurement of tumor oxygenation and other parameters characterizing tumor radiosensitivity

1986 • 6 citations

31P NMR spectroscopy of in vivo tumors

1984 • 5 citations

Preliminary Observations of Oxygen Levels in Microcirculation of Tumors in C3H Mice

1976 • 5 citations

Characterization of cell suspensions from solid tumors

1985 • 5 citations

RADIATION SENSITIVITY AND RECOVERY PATTERNS OF SPONTANEOUS AND ISOLOGOUSLY TRANSPLANTED MOUSE TUMORS

1964 • 4 citations

The Proliferative State of Clonogenic Cells In the Lewis Lung Tumour After Treatment With Cytotoxic Agents

1978 • 4 citations

The effect of recovery from potentially lethal damage on the determination of repair and repopulation in a murine tumour

1985 • 3 citations

Comparison of growth delay and cell survival as end-points of tumour response following treatment with combinations of cytotoxic agents.

1980 • 3 citations

Potentiation of Radiation Effects in Hypoxic HeLa Cells

1977 • 2 citations

Radiation response of autochthonous mammary tumors in SHN mice.

1981 • 2 citations

Reoxygenation between radiotherapy fractions in an experimental osteosarcoma

1985 • 2 citations

Tumor control and normal tissue tolerance in fractionated low dose rate radiotherapy

1986 • 1 citations