Human tumour xenografts in radiotherapeutic research

Radiobiology for the Radiologist.

1974 • 3,582 citations

Growth Kinetics of Tumours

1978 • 691 citations

Cyclic X-Ray Responses in Mammalian Cellsin Vitro¹

2012 • 505 citations

Relation of vascular proliferation to tumor growth.

1976 • 413 citations

Cyclic X-Ray Responses in Mammalian Cells in Vitro

1968 • 403 citations

Radiation biology in cancer research

1978 • 340 citations

An in vitro colony assay for human tumours grown in immune-suppressed mice and treated in vivo with cytotoxic agents

1978 • 296 citations

The Nude mouse in experimental and clinical research

1978 • 205 citations

The response to chemotherapy of a variety of human tumour xenografts

1983 • 167 citations

Improved immune-suppression techniques for the xenografting of human tumours

1978 • 131 citations

Fractionated radiation and hyperthermia: Experimental and clinical studies

1981 • 121 citations

The biological and clinical basis of radiosensitivity

1974 • 111 citations

Differential responses to x-irradiation of subpopulations of two heterogeneous human carcinomas in vitro.

1982 • 104 citations

The therapeutic response of three human tumor lines maintained in immune-suppressed mice.

1975 • 98 citations

Vascular structure of five human malignant melanomas grown in athymic nude mice

1982 • 93 citations

Immune-deficient animals

1985 • 82 citations

Variation in response of xenografts of colo-rectal carcinoma to chemotherapy

1978 • 74 citations

Thymus & self : immunobiology of the mouse mutant nude

1973 • 72 citations

Vascular changes in a human malignant melanoma xenograft following single-dose irradiation.

1984 • 72 citations

The relationship between the ‘cell loss factor’ and the immediate response to radiation in animal tumours

1972 • 72 citations

Radiosensitivity of Four Human Tumor Xenografts. Influence of Hypoxia and Cell-Cell Contact

1983 • 68 citations

In vitro radiation response of cells from four human tumors propagated in immune-suppressed mice.

1978 • 68 citations

The effect of radiation on tumour growth delay, cell survival and cure of the animal using a single tumour system

1977 • 68 citations

Vascular Changes in a Human Malignant Melanoma Xenograft Following Single-Dose Irradiation

1984 • 67 citations

Heterogeneous response and clonal drift of sensitivities of metastatic 13762NF mammary adenocarcinoma clones to gamma-radiation in vitro.

1983 • 66 citations

Survival Curve of a Human Melanoma in Nude Mice

1977 • 66 citations

Growth characteristics of human colorectal tumours during serial passage in immune-deprived mice

1978 • 62 citations

Radiation Response of the Cells of a Human Malignant Melanoma Xenograft. Effect of Hypoxic Cell Radiosensitizers

1981 • 57 citations

Human tumour xenografts established and serially transplanted in mice immunologically deprived by thymectomy, cytosine arabinoside and whole-body irradiation

1980 • 49 citations

Tumorigenicity of Human Malignant Lymphoblasts: Comparative Study With Unmanipulated Nude Mice, Antilymphocyte Serum-Treated Nude Mice, and X-Irradiated Nude Mice23

1980 • 49 citations

Growth characteristics of human melanoma xenografts

1982 • 49 citations

Human tumour xenografts: a critical appraisal.

1980 • 40 citations

Growth and Vascular Structure of Human Melanoma Xenografts

1984 • 38 citations

Hypoxic Fraction and Repair of Potentially Lethal Radiation Damage in Two Human Melanomas Transplanted into Nude Mice

1981 • 33 citations

Radiation Responsein Vitroof Cells from Five Human Malignant Melanoma Xenografts

1981 • 29 citations

Phenotypic and Functional Characteristics of ‘T-Like’ Cells in Nude Mice

1984 • 28 citations

Effect of Single Dose Irradiation on the Proliferation Kinetics in a Human Malignant Melanoma in Athymic Nude Mice

1980 • 26 citations

Enhancement of Heterotransplanted Human Tumor Graft Survival in Nude Mice Treated With Antilymphocyte Serum and in Congenitally Athymic-Asplenic (lasat) Mice2

1978 • 26 citations

Different growth rates of lung tumours in man and their xenografts in nude mice

1980 • 26 citations

Effect of cobalt-60 gamma rays and DTIC (5-(3,3 dimethyl-1-triazeno)-imidazole-4-carboxamide) on human malignant melanomas grown in athymic nude mice

1977 • 25 citations

Elevated macrophage activity in nude mice.

1984 • 24 citations

Radiation response of two human malignant melanomas grown in athymic nude mice

1981 • 23 citations

The radiosensitizing effect of metronidazole and misonidazole (Ro–07–0582) on a human malignant melanoma grown in the athymic mutant nude mouse

1978 • 21 citations

Immunodeficient Animals for Cancer Research

1981 • 19 citations

The effect of misonidazole on the radiation response of clonogenic human pancreatic carcinoma cells.

1978 • 18 citations

Effect of Single-Dose X Irradiation on the Growth Curves of a Human Malignant Melanoma Transplanted into Nude Mice

1981 • 18 citations

Clonogenic cell survival in cryopreserved human tumour cells

1981 • 15 citations

Radiosensitivity of nall human melanoma transplanted into nude mice: Repair, reoxygenation and dose fractionation

1982 • 15 citations

Differential responses to radiation and hyperthermia of cloned cell lines derived from a single human melanoma xenograft

1984 • 14 citations

Identification and separation of mouse and human components of heterotransplanted human tumours

1980 • 13 citations

Therapeutic Response of Human Tumour Xenografts in Immune-Suppressed Mice1

2015 • 13 citations

Radiosensitization by misonidazole of a human malignant melanoma grown in athymic nude mice

1980 • 13 citations

Radiosensitivity of the Cells of an Established Human Melanoma Cell Line and the Parent Melanoma Xenograft

1983 • 11 citations

Protective Role of Natural Killer Cells in Tumor Growth and Viral Infection in Mice

1984 • 11 citations

Effect of Clinically Relevant Irradiation Regimes on Human Malignant Melanomas Grown in Athymic Nude Mice

1977 • 9 citations

Tumour control following single-dose irradiation of a human melanoma xenograft

1983 • 9 citations

Effect of X Irradiation on a Heterotransplanted Human Colonic Carcinoma before and after a Change in the Cellular DNA Content

1983 • 8 citations

Radiation and heat sensitivity of cells from two slowly growing human melanoma xenografts

1984 • 8 citations

Radiosensitizing effect of misonidazole in acute and fractionated irradiation of a human osteosarcoma xenograft

1980 • 7 citations

Tumour Growth Delay and Cell Survival as Endpoints for Studying the Fraction of Hypoxic Cells in a Human Melanoma Transplanted into Nude Mice

1980 • 7 citations

Importance of vascularity, tumor bed and other general aspects in radiosensitivity

1974 • 4 citations

Radiation and heat sensitivity of cells from human melanoma xenografts. Lack of correlations with tumour growth parameters

1983 • 3 citations