Human tumour xenografts: a critical appraisal.

An in vitro colony assay for human tumours grown in immune-suppressed mice and treated in vivo with cytotoxic agents

1978 • 296 citations

Improved immune-suppression techniques for the xenografting of human tumours

1978 • 131 citations

Growth and antigenic properties of a biopsy‐derived Burkitt's lymphoma in thymus‐less (nude) mice

1973 • 131 citations

Human Brain Tumor Transplantation Into Nude Mice2

1979 • 120 citations

Chemotherapy of human colon cancer xenografts in athymic nude mice

1977 • 107 citations

The therapeutic response of three human tumor lines maintained in immune-suppressed mice.

1975 • 98 citations

Enhanced Post‐Irradiation Recovery of the Haemopoietic System In Animals Pretreated With A Variety of Cytotoxic Agents

1978 • 77 citations

The growth kinetics of xenografts of human colorectal tumours in immune deprived mice

1975 • 76 citations

Epidemic Nonmeningitic Lymphocytic-Choriomeningitis-Virus Infection

1966 • 76 citations

Variation in response of xenografts of colo-rectal carcinoma to chemotherapy

1978 • 74 citations

In vitro radiation response of cells from four human tumors propagated in immune-suppressed mice.

1978 • 68 citations

Survival Curve of a Human Melanoma in Nude Mice

1977 • 66 citations

In vitro and in vivo radiosensitivity of human tumour cells obtained from a pancreatic carcinoma xenograft

1976 • 62 citations

Growth characteristics of human colorectal tumours during serial passage in immune-deprived mice

1978 • 62 citations

The therapeutic response of bronchial carcinoma xenografts: a direct patient-xenograft comparison.

1980 • 56 citations

Human Tumours grown in Mice

1972 • 52 citations

A colony-forming assay for human tumour xenografts using agar in diffusion chambers

1976 • 49 citations

Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum

1977 • 43 citations

Gastrointestinal Cancer Studies in the Human to Nude Mouse Heterotransplant System

1977 • 42 citations

The Behaviour of Carcinoma of the Large Bowel in Man Following Transplantation into Immune Deprived Mice

1973 • 38 citations

Human neuroblastoma serially transplanted in nude mice and metastases

1978 • 31 citations

The interpretation of marker protein assays: a critical appraisal in clinical studies and a xenograft model.

1980 • 30 citations

Metastatic Spread of Human Tumour Implanted into Thymectomized, Antithymocyte Serum Treated Hamsters

1972 • 30 citations

In vitro chemosensitivity tests on xenografted human melanomas

1980 • 28 citations

Hexamethylmelamine-induced regression of human lung tumors growing in immune deprived mice.

1975 • 27 citations

Growth kinetics of human large bowel cancer growing in immune-deprived mice and some chemotherapeutic observations

2006 • 26 citations

Enhancement of Heterotransplanted Human Tumor Graft Survival in Nude Mice Treated With Antilymphocyte Serum and in Congenitally Athymic-Asplenic (lasat) Mice2

1978 • 26 citations

Effect of cobalt-60 gamma rays and DTIC (5-(3,3 dimethyl-1-triazeno)-imidazole-4-carboxamide) on human malignant melanomas grown in athymic nude mice

1977 • 25 citations

Effect of serial passage in nude athymic mice on the growth characteristics and chemotherapy responsiveness of 13762 and R3230AC mammary tumor xenografts.

1978 • 24 citations

Human lactic dehydrogenase as a marker for human tumor cells grown in athymic mice.

1977 • 22 citations

The growth and therapeutic response of human tumours in immune deficient mice.

1978 • 19 citations

The effect of misonidazole on the radiation response of clonogenic human pancreatic carcinoma cells.

1978 • 18 citations

Identification of murine endogenous xenotropic retrovirus in cultured multicellular tumour spheroids from nude‐mouse‐passaged nasopharyngeal carcinoma

1979 • 17 citations

Effects of cytotoxic agents on TdR incorporation and growth delay in human colonic tumour xenografts

1977 • 16 citations

Development of a method for assessing the antitumor activity of chemotherapeutic agents using human tumor xenografts.

1974 • 16 citations

Serial cytogenetic studies of human colonic tumour xenografts

1978 • 16 citations

The Sensitivity to Chemotherapeutic Agents of a Rat Tumour Grown in Immunosuppressed Mice

1971 • 16 citations

Growth of Human Melanoma in Nude Mice: Suppression by T-Lymphocytes From the Tumor Donor: Brief Communication 2

1977 • 14 citations

Chemotherapy of human choriocarcinoma transplanted to nude mice

1978 • 12 citations

Direct and serial transplantation of a Ph1 +ve human myeloblastoid tumour into nude mice

1977 • 11 citations

Metastatic growth of human tumour xenografts in thymectomised irradiated mice reconstituted with syngeneic bone marrow cells

1975 • 10 citations

GROWTH KINETICS OF A RAT MAMMARY TUMOUR TRANSPLANTED INTO IMMUNE‐SUPPRESSED MICE

1979 • 10 citations

Evaluation of cytotoxic agents in human colonic tumor xenografts and mouse gastrointestinal tissues using a 3H-thymidine fractional incorporation assay

1979 • 8 citations

Clonogenic cell survival curves for human melanoma xenografts using agar diffusion chamber and lung colony assays.

1980 • 6 citations