Is tumour radiosensitization by misonidazole a general phenomenon?

Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation

1979 • 523 citations

Electron-Affinic SensitizationVII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers

2012 • 353 citations

Electron-Affinic Sensitization: VII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers

1976 • 294 citations

Electron Affinic Sensitization: V. Radiosensitization of Hypoxic Bacteria and Mammalian Cells in Vitro by Some Nitroimidazoles and Nitropyrazoles

1974 • 229 citations

Hypoxic Sensitizers: Radiobiological Studies at the Cellular Level

1975 • 205 citations

The gross response of an experimental tumour to single doses of x-rays.

1967 • 172 citations

Selective chemotherapy of noncycling cells in an in vitro tumor model.

1974 • 170 citations

Effect of hyperthermia on differential cytotoxicity of a hypoxic cell radiosensitizer, Ro-07-0582, on mammalian cells in vitro

1977 • 140 citations

Tests of Two Electron-Affinic Radiosensitizers in Vivo Using Regrowth of an Experimental Carcinoma

1975 • 115 citations

Hypoxic Cell Radiosensitizers: Comparative Tests of Some Electron Affinic Compounds Using Epidermal Cell Survival in Vivo

1974 • 104 citations

The cellular proliferation kinetics of animal tumors.

1970 • 98 citations

Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice

1977 • 96 citations

Pharmacokinetic and Metabolic Studies of the Hypoxic Cell Radiosensitizer Misonidazole

1978 • 86 citations

The relationship between the ‘cell loss factor’ and the immediate response to radiation in animal tumours

1972 • 72 citations

Tumour Regrowth after Irradiation

1979 • 68 citations

A review of hypoxic cell radiosensitization in experimental tumors

1979 • 64 citations

Radiosensitization by Misonidazole (Ro 07-0582) The Importance of Timing and Tumor Concentration of Sensitizer

1978 • 59 citations

The toxicity of the radiosensitizer misonidazole towards hypoxic cellsin vitro: a model for mouse and man

1978 • 41 citations

Pharmacokinetic considerations in testing hypoxic cell radiosensitizers in mouse tumours

1979 • 37 citations

Distribution and tumour cytotoxicity of the radiosensitizer misonidazole (Ro-07-0582) in C57 mice

1979 • 29 citations

Cytotoxicity and radiosensitization in mouse and man

1978 • 26 citations

The nitroimidazoles as radiosensitizers and cytotoxic agents.

1978 • 23 citations

Sensitization of mouse tumours using fractionated X-irradiation.

1978 • 21 citations

Hypoxic cell sensitlzation by misonidazolein vivoandin vitro

1978 • 20 citations