Sp1 Is Required for the Early Response of α2(I) Collagen to Transforming Growth Factor-β1

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

The Molecular and Cellular Biology of Wound Repair

1988 • 1,508 citations

Cell Biology of Extracellular Matrix

1988 • 1,498 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta.

1987 • 736 citations

Sp1-mediated transcriptional activation is repressed by Sp3.

1994 • 692 citations

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

1988 • 620 citations

THE FAMILY OF COLLAGEN GENES

1990 • 511 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability.

1988 • 420 citations

The role of extracellular matrix in postinflammatory wound healing and fibrosis

1994 • 415 citations

Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells.

1991 • 381 citations

Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo.

1991 • 320 citations

An AP-1 Binding Sequence Is Essential for Regulation of the Human α2(I) Collagen (COL1A2) Promoter Activity by Transforming Growth Factor-β

1996 • 312 citations

Transforming growth factor-beta stimulates alpha 2(I) collagen gene expression through a cis-acting element that contains an Sp1-binding site.

1994 • 311 citations

The retinoblastoma gene product regulates Sp1-mediated transcription.

1992 • 253 citations

Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice.

1995 • 239 citations

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression.

1995 • 212 citations

The Retinoblastoma Gene Product RB Stimulates Spl-Mediated Transcription by Liberating Spl from a Negative Regulator

1994 • 189 citations

Cytokines in rheumatoid arthritis.

1995 • 170 citations

Cell-specific Induction of Distinct Oncogenes of the Jun Family Is Responsible for Differential Regulation of Collagenase Gene Expression by Transforming Growth Factor-β in Fibroblasts and Keratinocytes

1996 • 157 citations

Organization of the human pro-alpha 2(I) collagen gene.

1987 • 156 citations

A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic mice.

1996 • 148 citations

Transcriptional Regulation of the Human α2(I) Collagen Gene

1996 • 148 citations

Acetaldehyde increases collagen gene transcription in cultured human fibroblasts.

1987 • 143 citations

Collagen and Other Matrix Glycoproteins in Embryogenesis

1991 • 139 citations

Differential utilization of regulatory domains within the alpha 1(I) collagen promoter in osseous and fibroblastic cells.

1992 • 134 citations

Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen genes.

1990 • 127 citations

Characterization of a GC-rich Region Containing Sp1 Binding Site(s) as a Constitutive Responsive Element of the α2(I) Collagen Gene in Human Fibroblasts

1995 • 127 citations

Regulation of expression of the type I collagen genes

1993 • 121 citations

Wound Repair

1988 • 113 citations

Overlapping Pathways Mediate the Opposing Actions of Tumor Necrosis Factor-α and Transforming Growth Factor-β on α2(I) Collagen Gene Transcription

1995 • 110 citations

Separate binding sites for nuclear factor 1 and a CCAAT DNA binding factor in the mouse alpha 2(I) collagen promoter.

1987 • 109 citations

Monoclonal antibodies against eucaryotic ribosomes. Use to characterize a ribosomal protein not previously identified and antigenically related to the acidic phosphoproteins P1/P2.

1982 • 109 citations

Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events.

1991 • 102 citations

Association of p107 with Sp1: Genetically Separable Regions of p107 Are Involved in Regulation of E2F- and Sp1-Dependent Transcription

1995 • 98 citations

Transcription of the KpnI families of long interspersed DNAs in human cells

1983 • 87 citations

Point mutations and small substitution mutations in three different upstream elements inhibit the activity of the mouse alpha 2(I) collagen promoter.

1988 • 84 citations

Tissue-specific expression of the mouse alpha 2(I) collagen promoter. Studies in transgenic mice and in tissue culture cells.

1992 • 78 citations

Minimal DNA sequences that control the cell lineage-specific expression of the pro alpha 2(I) collagen promoter in transgenic mice.

1992 • 71 citations

Transcriptional interactions of transforming growth-factor-β with pro-inflammatory cytokines

1993 • 53 citations

Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.

1993 • 50 citations

Requirements for Transforming Growth Factor-β Regulation of the Pro-α2(I) Collagen and Plasminogen Activator Inhibitor-1 Promoters

1995 • 50 citations

Antagonistic Regulation of a Proline-rich Transcription Factor by Transforming Growth Factor β and Tumor Necrosis Factor α

1996 • 37 citations

Evidence for three major transcription activation elements in the proximal mouse proalpha2(I) collagen promoter

1996 • 32 citations

Tyrosine Dephosphorylation of Nuclear Proteins Mimics Transforming Growth Factor β1 Stimulation of α2(I) Collagen Gene Expression

1995 • 30 citations

Identification of an upstream regulatory region essential for cell type-specific transcription of the pro-alpha 2(V) collagen gene (COL5A2).

1992 • 28 citations