Minimal DNA sequences that control the cell lineage-specific expression of the pro alpha 2(I) collagen promoter in transgenic mice.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1990 • 1,002 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta.

1987 • 736 citations

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.

1991 • 677 citations

A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

1988 • 620 citations

Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

1990 • 600 citations

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1987 • 578 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors

1988 • 452 citations

Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene

1983 • 422 citations

Appearance and distribution of collagens and laminin in the early mouse embryo

1980 • 395 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

In situ hybridization analysis of TGFβ3 RNA expression during mouse development: comparative studies with TGFβ1 and β2

1990 • 325 citations

Differential expression of TGF β1, β2 and β3 genes during mouse embryogenesis

1991 • 296 citations

Expression of the mouse α1 (II) collagen gene is not restricted to cartilage during development

1991 • 264 citations

Transforming Growth Factor β: Biochemistry and Roles in Embryogenesis, Tissue Repair and Remodeling, and Carcinogenesis

1988 • 255 citations

The dopamine β-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice

1991 • 251 citations

TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis

1990 • 239 citations

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.

1984 • 229 citations

Colocalization of TGF-beta 1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis*

1990 • 226 citations

Selective Activation of Transcription by a Novel CCAAT Binding Factor

1988 • 206 citations

Thyroid Hormone Regulates the Mouse Thyrotropin β-Subunit Gene Promoter in Transfected Primary Thyrotropes

1989 • 203 citations

A CCAAT DNA binding factor consisting of two different components that are both required for DNA binding.

1988 • 175 citations

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

1991 • 167 citations

The localization and synthesis of some collagen types in developing mouse embryos

1979 • 142 citations

Transforming-growth-factor-β activation elements in the distal promoter regions of the rat α1 type I collagen gene

1991 • 138 citations

Differential utilization of regulatory domains within the alpha 1(I) collagen promoter in osseous and fibroblastic cells.

1992 • 134 citations

Transcriptional Control of the Mouse α₂(I) Collagen Gene: Functional Deletion Analysis of the Promoter and Evidence for Cell-Scific Expression

1986 • 89 citations

Point mutations and small substitution mutations in three different upstream elements inhibit the activity of the mouse alpha 2(I) collagen promoter.

1988 • 84 citations

An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice.

1991 • 83 citations

Tissue-specific expression of the mouse alpha 2(I) collagen promoter. Studies in transgenic mice and in tissue culture cells.

1992 • 78 citations

Temporal and spatial patterns of transforming growth factor-β1 expression in developing rat molars

1990 • 77 citations

Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice.

1986 • 72 citations

Conservation of binding sites for regulatory factors in the coordinately expressed α1(I) and α2(I) collagen promoters

1991 • 71 citations

The Role of TGFβ in Mouse Development^a

1990 • 45 citations

An Upstream Regulatory Region Mediates High-Level, TissueSpecific Expression of the Human al(I) Collagen Gene in Transgenic Mice

1991 • 28 citations