Acetaldehyde increases collagen gene transcription in cultured human fibroblasts.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.

1985 • 839 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

Variety in the level of gene control in eukaryotic cells

1982 • 772 citations

Cloning and characterization of five overlapping cDNAs specific for the human proα 1(I) collagen chain

1982 • 496 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

Pathogenesis of alcohol-induced accumulation of protein in the liver.

1977 • 308 citations

The determination of acetaldehyde in blological samples by head-space gas chromatography

1977 • 306 citations

The hepatic extracellular matrix. II. Electron immunohistochemical studies in rats with CCl4-induced cirrhosis.

1985 • 267 citations

Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts.

1986 • 263 citations

Perivenular Fibrosis in Alcoholic Liver Injury: Ultrastructure and Histologic Progression

1982 • 249 citations

Collagen biosynthesis during connective tissue development in chick embryo

1972 • 218 citations

Histogenesis of alcoholic fibrosis and cirrhosis in the baboon.

1980 • 208 citations

Cloning a cDNA for the pro-alpha 2 chain of human type I collagen.

1981 • 192 citations

Medical Disorders of Alcoholism: Pathogenesis and Treatment.

1983 • 169 citations

Fine structural analysis of the human pro-alpha 1 (I) collagen gene. Promoter structure, AluI repeats, and polymorphic transcripts.

1985 • 162 citations

The distribution and metabolism of acetaldehyde in rats during ethanol oxidation—I

1977 • 159 citations

Lymphocyte modulation of fibroblast function in vitro: stimulation and inhibition of collagen production by different effector molecules.

1984 • 139 citations

Acetaldehyde and lactate stimulate collagen synthesis of cultured baboon liver myofibroblasts

1984 • 139 citations

Binding of acetaldehyde to rat liver microsomes: Enhancement after chronic alcohol consumption

1981 • 128 citations

Procollagen production and procollagen messenger RNA levels and activity in human lung fibroblasts during periods of rapid and stationary growth.

1981 • 97 citations

DNA and chromatin structure of the human alpha 1 (I) collagen gene.

1984 • 90 citations

Acetaldehyde Stimulates Collagen and Noncollagen Protein Production by Human Fibroblasts

1984 • 88 citations

Specifically decreased collagen biosynthesis in scurvy dissociated from an effect on proline hydroxylation and correlated with body weight loss. In vitro studies in guinea pig calvarial bones.

1983 • 86 citations

The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance

1985 • 85 citations

Bacterial cell wall-induced hepatic granulomas. An in vivo model of T cell-dependent fibrosis.

1986 • 82 citations

Medical Disorders of Alcoholism: Pathogenesis and Treatment

1983 • 74 citations

Enhancement of acetaldehyde-protein adduct formation by l-ascorbate

1984 • 66 citations

The Rate of Synthesis of Glycosaminoglycans and Collagen by Fibroblasts Cultured from Adult Human Liver Biopsies

1977 • 59 citations

Transcriptional regulation of type I collagen genes in cultured fibroblasts by a factor isolated from thioacetamide-induced fibrotic rat liver.

1984 • 59 citations

Role of Acetaldehyde in the Ethanol-Induced Impairment of Glycoprotein Metabolism in Rat Liver Slices

1977 • 58 citations

Hepatocyte collagen production in vivo in normal rats.

1986 • 58 citations

Nonparenchymal Cells Cultivated from Explants of Fibrotic Liver Resemble Endothelial and Smooth Muscle Cells from Blood Vessel Walls

1982 • 56 citations

Development and Use of a Rat Albumin cDNA Clone to Evaluate the Effect of Chronic Ethanol Administration on Hepatic Protein Synthesis†

1983 • 55 citations

Use of in situ hybridization to identify collagen and albumin mRNAs in isolated mouse hepatocytes.

1983 • 41 citations

Selective inhibition of collagen synthesis by the Ca2+ ionophore A23187 in cultured human fibroblasts.

1986 • 35 citations

Collagen degradation in human lung fibroblasts: Extent of degradation, role of lysosomal proteases, and evaluation of an alternate hypothesis

1984 • 32 citations

Non-selective decrease of collagen synthesis by cultured fetal lung fibroblasts after non-lethal doses of ethanol

1980 • 13 citations

[3H]tryptophan-[14C]proline dual label method for the simultaneous determination of collagen and noncollagen protein production

1984 • 9 citations