Cytokine networking in the placenta

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Interleukin-6 and the acute phase response

1990 • 2,740 citations

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

1991 • 1,880 citations

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1991 • 1,864 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

1991 • 1,734 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood

1984 • 1,345 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Cytokines in context.

1991 • 808 citations

Potential antiinflammatory effects of interleukin 4: suppression of human monocyte tumor necrosis factor alpha, interleukin 1, and prostaglandin E2.

1989 • 741 citations

Infection and Preterm Labor

1988 • 717 citations

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

1989 • 711 citations

Stimulation of Muscle Protein Degradation and Prostaglandin E₂Release by Leukocytic Pyrogen (Interleukin-1)

1983 • 689 citations

Infection and labor V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes

1989 • 684 citations

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.

1990 • 679 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines.

1990 • 642 citations

Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).

1981 • 614 citations

The Receptor for Ciliary Neurotrophic Factor

1991 • 604 citations

Infection and labor

1989 • 600 citations

Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor.

1991 • 593 citations

A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein.

1991 • 571 citations

Amniotic fluid interleukin 6 in preterm labor. Association with infection.

1990 • 557 citations

A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor β-chain

1989 • 551 citations

Interleukin-8 (IL-8): The Major Neutrophil Chemotactic Factor in the Lung

1991 • 550 citations

Multiple actions of interleukin 6 within a cytokine network

1988 • 536 citations

Cytokines as communication signals between leukocytes and endothelial cells

1989 • 528 citations

Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8.

1989 • 515 citations

Interleukin 10: a novel stimulatory factor for mast cells and their progenitors.

1991 • 514 citations

Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities.

1986 • 514 citations

Human Lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization

1985 • 509 citations

Apparent role of the macrophage growth factor, CSF-1, in placental development

1987 • 506 citations

Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy

1990 • 504 citations

Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells.

1990 • 484 citations

Interferon-like sequence of ovine trophoblast protein secreted by embryonic trophectoderm

1987 • 464 citations

Infection and labor

1989 • 441 citations

Endocrine control of parturition

1979 • 432 citations

Infection in the pathogenesis of preterm labor.

1988 • 430 citations

Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

1988 • 401 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

Intraamniotic infection and the onset of labor in preterm premature rupture of the membranes

1988 • 367 citations

Neutrophil attractant/activating peptide-1 / interleukin-8 in term and preterm parturition

1991 • 353 citations

Regulation of colony-stimulating factor 1 during pregnancy.

1986 • 314 citations

Interleukins and the immune system 1.

1989 • 312 citations

Cachectin/tumor necrosis factor-alpha formation in human decidua. Potential role of cytokines in infection-induced preterm labor.

1989 • 307 citations

Interlukin-1 stimulates prostaglandin biosynthesis by human amnion

1989 • 301 citations

Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity.

1988 • 297 citations

Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

1989 • 288 citations

The immunostimulatory effect of T cells and T cell lymphokines on murine fetally derived placental cells.

1987 • 282 citations

Evidence for an Epidermal Cytokine Network

1990 • 278 citations

Human Endometrium: An Active Site of Cytokine Production and Action*

1991 • 274 citations

Altered cytosol/membrane enzyme redistribution on interleukin-3 activation of protein kinase C

1985 • 255 citations

Interleukin 1, interleukin 6 and tumor necrosis factor in infection, inflammation and immunity

1988 • 252 citations

Premature labor. II. Bacterial sources of phospholipase.

1981 • 250 citations

Interleukin-1β, human leukocyte antigen HLA-DRα, and transforming growth factor-β expression in endom trium, placenta, and placental membranes

1990 • 248 citations

IL-4 inhibits the expression of IL-8 from stimulated human monocytes.

1990 • 244 citations

T Cell‐Replacing Factor (TRF)/Interleukin 5 (IL‐5): Molecular and Functional Properties

1988 • 241 citations

Cytokine networks in the uteroplacental unit: Macrophages as pivotal regulatory cells

1989 • 240 citations

Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes.

1987 • 236 citations

Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5.

1987 • 236 citations

Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases.

1989 • 235 citations

Synergistic stimulation of fibroblast prostaglandin production by recombinant interleukin 1 and tumor necrosis factor.

1987 • 233 citations

The association of chorioamnionitis with preterm delivery.

1985 • 233 citations

Characterization of the human B cell stimulatory factor 1 receptor.

1987 • 232 citations

Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells

1991 • 232 citations

Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-beta.

1989 • 229 citations

Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes.

1988 • 227 citations

Human decidua: a source of interleukin-1.

1989 • 221 citations

Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes.

1990 • 214 citations

Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes.

1992 • 204 citations

Macrophage populations in the human placenta and amniochorion.

1984 • 202 citations

Prostaglandin biosynthesis by human decidual cells: Effects of inflammatory mediators

1990 • 197 citations

Coordinate regulation of immune and inflammatory responses by T cell‐derived lymphokines

1988 • 197 citations

Eosinophil differentiation factor also has B-cell growth factor activity: proposed name interleukin 4.

1986 • 194 citations

Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.

1983 • 187 citations

Expression of the c-fms proto-oncogene and of the cytokine, CSF-1, during mouse embryogenesis

1989 • 187 citations

Preterm labor: Stimulation of arachidonic acid metabolism in human amnion cells by bacterial products

1987 • 187 citations

Amniotic fluid interleukin-1 in spontaneous labor at term.

1990 • 182 citations

Transcriptional regulation of the human prointerleukin 1 beta gene.

1987 • 172 citations

INTERFERON SEQUENCE HOMOLOGY AND RECEPTOR BINDING ACTIVITY OF OVINE TROPHOBLAST ANTILUTEOLYTIC PROTEIN

1987 • 172 citations

Trophoblast-Derived Interleukin-6 (IL-6) Regulates Human Chorionic Gonadotropin Release through IL-6 Receptor on Human Trophoblasts*

1990 • 162 citations

Control of Parturition in Man

1977 • 160 citations

Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders.

1987 • 158 citations

Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation

1989 • 154 citations

Effects of recombinant interleukin 11 on human megakaryocyte progenitor cells.

1991 • 151 citations

Immunohistological characterization of lymphoid cell populations in the early human placental bed.

1984 • 147 citations

PGE2-mediated immunosuppression by first trimester human decidual cells blocks activation of maternal leukocytes in the decidua with potential anti-trophoblast activity

1989 • 134 citations

Decidual cell biosynthesis of interleukin-6: regulation by inflammatory cytokines

1992 • 134 citations

Expression cloning of cDNA encoding a novel human hematopoietic growth factor: human homologue of murine T-cell growth factor P40

1989 • 134 citations

High homology between a trophoblastic protein (trophoblastin) isolated from ovine embryo and α‐interferons

1988 • 125 citations

Silent chorioamnionitis as a cause of preterm labor refractory to tocolytic therapy

1984 • 120 citations

A transforming growth factor beta 2 (TGF-beta 2)-like immunosuppressive factor in amniotic fluid and localization of TGF-beta 2 mRNA in the pregnant uterus.

1990 • 120 citations

InVitroMetabolism of 25-Hydroxycholecalciferol by Isolated Cells from Human Decidua*

1985 • 120 citations

EFFECT OF BACTERIAL PRODUCTS ON PROSTAGLANDIN E PRODUCTION BY AMNION CELLS

1985 • 117 citations

Demonstration of tumor necrosis factor in human amniotic fluids and supernatants of placental and decidual tissues.

1988 • 117 citations

Isolation and characterization of an expressible cDNA encoding human IL-3. Induction of IL-3 mRNA in human T cell clones.

1988 • 113 citations

Maternal T cells promote placental growth and prevent spontaneous abortion

1988 • 109 citations

Endotoxin stimulates prostaglandin E2 production by human amnion.

1988 • 109 citations

Prostaglandin production by human chorion laeve cells in response to inflammatory mediators

1991 • 107 citations

Active suppression of host-vs graft reaction in pregnant mice. IX. Soluble suppressor activity obtained from allopregnant mouse decidua that blocks the cytolytic effector response to IL-2 is related to transforming growth factor-beta.

1988 • 107 citations

Endogenous Prostaglandins in Human Parturition

1979 • 106 citations

Phosphatidylinositol-Derived Precursors and Signals

1990 • 103 citations

Expression of colony-stimulating factors and inflammatory cytokines in the uterus of CD1 mice during Days 1 to 3 of pregnancy

1992 • 97 citations

Interleukin-1 alpha and tumor necrosis factor alpha cause placental injury in the rat.

1989 • 90 citations

Evaluation of the pregnancy immunotrophism hypothesis by assessment of the reproductive performance of young adult mice of genotype scid/scid.bg/bg

1990 • 89 citations

Endothelin increases cytoplasmic calcium and myosin phosphorylation in human myometrium

1990 • 87 citations

The course of labor in term patients with chorioamnionitis

1983 • 82 citations

Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFN-gamma.

1989 • 81 citations

Production of Interleukin-6 by Fetal and Maternal Cells in Vivo during Intraamniotic Infection and in Vitro after Stimulation with Interleukin-1

1991 • 75 citations

Immunohistological characterization of the decidual leucocytic infiltrate related to endometrial gland epithelium in early human pregnancy.

1985 • 74 citations

Production of prostaglandin E2 by human amnion in vitro in response to addition of media conditioned by microorganisms associated with chorioamnionitis and preterm labor

1990 • 74 citations

The effect of human placental protein 14 (PP14) on the production of interleukin-1 from mitogenically stimulated mononuclear cell cultures.

1990 • 71 citations

IL-1 serves as a secondary signal for IL-9 expression.

1991 • 71 citations

Prostaglandin E2 inhibits human T-cell proliferation after crosslinking of the CD3-Ti complex by directly affecting T cells at an early step of the activation process

1987 • 70 citations

Vitamin D and Pregnancy: The Maternal-Fetal Metabolism of Vitamin D

1981 • 67 citations

Decidual Activation in Parturition: Examination of Amniotic Fluid for Mediators of the Inflammatory Response^a

1991 • 64 citations

INHIBITION OF PROSTACLANDIN SYNTHESIS BY HUMAN AMNIOTIC FLUID: ACUTE REDUCTION IN INHIBITORY ACTIVITY OF AMNIOTIC FLUID OBTAINED DURING LABOR

1982 • 63 citations

Regulation of the pathophysiology of tumor necrosis factor.

1990 • 62 citations

Prostaglandin production by amnion and decidual cells in response to bacterial products

1991 • 57 citations

Biosynthesis of interleukin-6 by cultured human chorion laeve cells: regulation by cytokines.

1992 • 57 citations

Human tumour necrosis factor-alpha (TNF-alpha) directly stimulates arachidonic acid release in human neutrophils.

1990 • 54 citations

The role of prostaglandins in human parturition

1990 • 51 citations

Localization of leukocytes and cytokines in chorionic villi of normal placentas and complete hydatidiform moles

1990 • 49 citations

The cytokine receptor superfamily

1991 • 45 citations

Role of Interferon-γ in Counteracting the Suppressive Effects of Transforming Growth Factor-β2 and Glucocorticoids on the Production of Tumor Necrosis Factor-α

1990 • 44 citations

Interleukin-1 stimulates prostacyclin production by cultured human endothelial cells by increasing arachidonic acid mobilization and conversion.

1990 • 41 citations

Protein Kinase-C Activation Is Required for Oxytocin-Induced Prostaglandin Production in Human Amnion Cells*

1991 • 39 citations

Endothelin-1,2 levels are increased in the amniotic fluid of women with preterm labor and microbial invasion of the amniotic cavity

1992 • 39 citations

Endothelin production by amnion and its regulation by cytokines

1991 • 32 citations

Stimulation of arachidonic acid metabolism: Differences in potencies of recombinant human interleukin-1α and interleukin-1β on two cell types

1986 • 27 citations

Administration of extra-amniotic arachidonic acid and the suppression of uterine prostaglandin synthesis during pregnancy in the rhesus monkey

1978 • 25 citations

Enhancement of ectopic β-human chorionic gonadotrophin expression by interferon-α

1989 • 25 citations

Effects of pregnancy, oxytocin, ovine trophoblast protein-1 and their interactions on endometrial production of prostaglandin F2α in vitro in perifusion chambers

1989 • 21 citations

Cytokines: Molecular and Biological Characteristics

1988 • 18 citations

Catecholamines modulate epidermal growth factor-induced prostaglandin E2 production in amnion-like (WISH) cells by means of a cyclic adenosine monophosphate-dependent pathway

1992 • 17 citations

Colony-Stimulating Factor I in the Mouse and Human Uteroplacental Unit

1991 • 14 citations

Regulation of eicosanoid biosynthesis during pregnancy and parturition

1987 • 14 citations

Endothelin Transfer and Endothelin Effects on Water Transfer in Human Fetal Membranes

1992 • 12 citations

Induction and Regulation of Interleukin-8 Gene Expression

1991 • 11 citations

Granulocyte colony-stimulating factor modulation of cytokine receptors on murine bone marrow cells. In vivo and in vitro studies.

1991 • 10 citations

The Molecular Genetics of Beta‐2 Interferon/Interleukin‐6 (IFNβ2/IL6)^a

1989 • 8 citations

Fetal, Placental, and Maternal Hormones

1984 • 5 citations

Interleukin 1 signal transduction.

1991 • 3 citations

Actions of interleukin-4 on prostaglandin production by human amnion

1992 • 2 citations

The effects of interleukin-2 on amnion prostaglandin-E2 biosynthesis

1992 • 1 citations