Interleukin-1 stimulates prostacyclin production by cultured human endothelial cells by increasing arachidonic acid mobilization and conversion.

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

Prostaglandins and Thromboxanes

1978 • 1,310 citations

Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.

1988 • 990 citations

Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells.

1984 • 944 citations

Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

1988 • 401 citations

Prostacyclin Synthesis Induced in Vascular Cells by Interleukin-1

1985 • 364 citations

Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action.

1986 • 259 citations

Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase.

1985 • 219 citations

Interleukin 1 stimulates platelet-activating factor production in cultured human endothelial cells.

1986 • 172 citations

Exaggerated human vascular cell prostaglandin biosynthesis mediated by monocytes: role of monokines and interleukin 1.

1985 • 142 citations

Modulation of endothelial cell functions by different molecular species of interleukin 1

1987 • 137 citations

Interleukin 1 amplifies receptor-mediated activation of phospholipase A2 in 3T3 fibroblasts.

1988 • 110 citations

Prostacyclin biosynthesis in cultured vascular endothelium is limited by deactivation of cyclooxygenase.

1983 • 74 citations

Prostacyclin production by perturbed bovine aortic endothelial cells in culture

1984 • 68 citations

Alkyl-ether phosphoglycerides influence calcium fluxes into human endothelial cells.

1985 • 67 citations

Prostaglandins and Thromboxanes

1978 • 59 citations

Endothelial functional responses and increased vascular permeability induced by polycations.

1988 • 58 citations

Prostacyclin production by human endothelial and bovine smooth muscle cells in culture

1983 • 49 citations

The stimulations of arachidonic acid metabolism by recombinant murine interleukin 1 and tumor promoters or 1-oleoyl-2-acetyl-glycerol are synergistic.

1985 • 31 citations

Thrombin and bradykinin modulate prostaglandin synthetase independently of phospholipase.

1980 • 11 citations

Recovery of prostacyclin production by cultured bovine smooth muscle cells after aspirin inhibition: effect of serum replacement and concentration in culture medium

1983 • 9 citations