New insights into the auxiliary domains of eukaryotic RNA binding proteins

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

SR proteins: a conserved family of pre-mRNA splicing factors.

1992 • 766 citations

RNA recognition: towards identifying determinants of specificity

1991 • 739 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A

1990 • 622 citations

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

1992 • 619 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

RIBOSOMAL RNA AND TRANSLATION

1991 • 489 citations

mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.

1986 • 455 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

1992 • 367 citations

Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells.

1990 • 359 citations

Cloning and characterization of PSF, a novel pre-mRNA splicing factor.

1993 • 359 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA

1993 • 332 citations

Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities.

1988 • 327 citations

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

1989 • 314 citations

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA

1993 • 309 citations

The elav Gene Product of Drosophila , Required in Neurons, Has Three RNP Consensus Motifs

1988 • 302 citations

Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B" and their cognate RNAs

1990 • 283 citations

GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast.

1992 • 270 citations

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

1988 • 266 citations

Modular structure of transcription factors: Implications for gene regulation

1991 • 260 citations

RNA recognition: A family matter?

1993 • 253 citations

Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains.

1993 • 243 citations

General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection.

1992 • 241 citations

Peptides with sequences similar to glycine, arginine-rich motifs in proteins interacting with RNA are efficiently recognized by methyltransferase(s) modifying arginine in numerous proteins

1993 • 236 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins.

1987 • 229 citations

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1991 • 224 citations

The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.

1991 • 218 citations

Pre-mRNA Splicing in Yeast

1989 • 209 citations

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

1992 • 209 citations

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit.

1992 • 203 citations

cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins.

1987 • 203 citations

Protein Enhancement of Hammerhead Ribozyme Catalysis

1993 • 199 citations

The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site.

1992 • 198 citations

The glycine-rich domain of nucleolin has an unusual supersecondary structure responsible for its RNA-helix-destabilizing properties.

1992 • 194 citations

Functional domains of the human splicing factor ASF/SF2.

1993 • 188 citations

Interaction of the RNA-binding domain of the hnRNP C proteins with RNA.

1992 • 186 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

Specific binding of arginine to TAR RNA.

1992 • 174 citations

Mammalian heterogeneous nuclear ribonucleoprotein complex protein A1. Large-scale overproduction in Escherichia coli and cooperative binding to single-stranded nucleic acids.

1988 • 170 citations

The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins

1989 • 156 citations

Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing

1993 • 152 citations

Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs.

1991 • 148 citations

Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA.

1990 • 139 citations

Renaturation of complementary DNA strands mediated by purified mammalian heterogeneous nuclear ribonucleoprotein A1 protein: implications for a mechanism for rapid molecular assembly.

1990 • 139 citations

The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs.

1992 • 131 citations

Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.

1992 • 128 citations

Molecular cloning of Xenopus fibrillarin, a conserved U3 small nuclear ribonucleoprotein recognized by antisera from humans with autoimmune disease.

1990 • 127 citations

Proton, carbon-13, and nitrogen-15 NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins

1992 • 125 citations

Concerted activities of the RNA recognition and the glycine‐rich C‐terminal domains of nucleolin are required for efficient complex formation with pre‐ribosomal RNA

1992 • 119 citations

Studies of the strand-annealing activity of mammalian hnRNP complex protein A1

1990 • 114 citations

Protein and cDNA sequence of a glycine-rich, dimethylarginine-containing region located near the carboxyl-terminal end of nucleolin (C23 and 100 kDa).

1986 • 109 citations

Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1.

1986 • 107 citations

Human SR Proteins and Isolation of a cDNA Encoding SRp75

1993 • 105 citations

The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins

1993 • 103 citations

Heterogeneous nuclear ribonucleoprotein A1 catalyzes RNA.RNA annealing.

1992 • 98 citations

Rapid renaturation of complementary DNA strands mediated by cationic detergents: a role for high-probability binding domains in enhancing the kinetics of molecular assembly processes.

1991 • 93 citations

Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors

1993 • 92 citations

Phosphorylation of human hnRNP protein A1 abrogatesin vitrostrand annealing activity

1993 • 91 citations

Alternative splicing in the human gene for the core protein A1 generates another hnRNP protein.

1990 • 86 citations

Interactions of the A1 heterogeneous nuclear ribonucleoprotein and its proteolytic derivative, UP1, with RNA and DNA: Evidence for multiple RNA binding domains and salt-dependent binding mode transitions

1991 • 78 citations

Isolation of an active gene encoding human hnRNP protein A1

1989 • 77 citations

Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA.

1993 • 74 citations

Isolation of RRM-type RNA-binding protein genes and the analysis of their relatedness by using a numerical approach.

1993 • 64 citations

Cell Cycle-Regulated Phosphorylation of the Pre-mRNA-Binding (Heterogeneous Nuclear Ribonucleoprotein) C Protein

1993 • 63 citations

Recombinant hnRNP protein A1 and its N-terminal domain show preferential affinity for oligodeoxynucleotides homologous to intron/exon acceptor sites

1990 • 61 citations

RNA annealing activity is intrinsically associated with U2AF

1993 • 59 citations

Rapid assembly and disassembly of complementary DNA strands through an equilibrium intermediate state mediated by A1 hnRNP protein.

1992 • 57 citations

Mammalian Heterogeneous Ribonucleoprotein A1 and its Constituent Domains

1993 • 52 citations

Human SR proteins and isolation of a cDNA encoding SRp75.

1993 • 49 citations

PUB1: a major yeast poly(A)+ RNA-binding protein.

1993 • 46 citations

Cell cycle-regulated phosphorylation of the pre-mRNA-binding (heterogeneous nuclear ribonucleoprotein) C proteins.

1993 • 44 citations

Characterization of a 48‐kDa nucleic‐acid‐binding fragment of nucleolin

1989 • 35 citations

An RNA-binding protein gene (RBP1) of Saccharomyces cerevisiae encodes a putative glucose-repressible protein containing two RNA recognition motifs

1993 • 33 citations

Changes in heterogeneous nuclear RNP core polypeptide complements during the cell cycle.

1987 • 30 citations

Solar systems in the making

1990 • 12 citations

Fibrillarin and U3 RNA expression during Xenopus oogenesis and embryo development

1990 • 12 citations