Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

SR proteins: a conserved family of pre-mRNA splicing factors.

1992 • 766 citations

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1991 • 708 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein

1991 • 433 citations

Structure of spliceosomal snRNPs and their role in pre-mRNA splicing

1990 • 407 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway.

1991 • 297 citations

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

1988 • 266 citations

Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

1992 • 244 citations

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

1992 • 209 citations

Pre-mRNA Splicing in Yeast

1989 • 209 citations

Antisense probing of the human U4U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides

1989 • 169 citations

Mapping of B cell epitopes on small nuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies.

1989 • 164 citations

Splice site selection and ribonucleoprotein complex assembly during in vitro pre-mRNA splicing.

1988 • 163 citations

The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins

1989 • 156 citations

U1-Specific Protein C needed for Efficient Complex Formation of U1 snRNP with a 5′ Splice Site

1990 • 135 citations

Purification of small nuclear ribonucleoprotein particles with antibodies against modified nucleosides of small nuclear RNAs

1990 • 68 citations

Characterisation of human and murine snRNP proteins by two-dimensional gel electrophoresis and phosphopeptide analysis of U1-specific 70K protein variants

1990 • 63 citations

RNA-protein organization of U1, U5 and U4-U6 small nuclear ribonucleoproteins in HeLa cells

1986 • 62 citations

Adenosine phosphorothioates (ATP alpha S and ATP tau S) differentially affect the two steps of mammalian pre-mRNA splicing.

1992 • 53 citations

An ATP-independent U2 small nuclear ribonucleoprotein particle/precursor mRNA complex requires both splice sites and the polypyrimidine tract.

1992 • 41 citations

Polypeptide components of human small nuclear ribonucleoproteins.

1983 • 35 citations

Recognition of 5' and 3' splice site sequences in pre-mRNA studied with a filter binding technique.

1987 • 26 citations

The 5′ end domain of U2 snRNA is required to establish the interaction of U2 snRNP with U2 auxiliary factor(s) during mammalian spliceosome assembly

1991 • 10 citations