Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix

1995 • 1,184 citations

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

1992 • 1,047 citations

Type IV collagenases in tumor invasion and metastasis

1990 • 502 citations

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

1991 • 491 citations

Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

1990 • 466 citations

Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.

1994 • 466 citations

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

1989 • 462 citations

Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression [published erratum appears in J Cell Biol 1996 Feb;132(4):following 752]

1994 • 405 citations

Extracellular Matrix Degradation

1991 • 262 citations

Differences in secretion of the proteinase cathepsin B at the edges of human breast carcinomas and fibroadenomas

1978 • 260 citations

Extracellular matrix regulates expression of the TGF-beta 1 gene.

1993 • 260 citations

Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells.

1992 • 219 citations

Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin.

1992 • 204 citations

Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor.

1991 • 178 citations

A Novel Function for the nm23-H1 Gene: Overexpression in Human Breast Carcinoma Cells Leads to the Formation of Basement Membrane and Growth Arrest

1994 • 157 citations

Cathepsin D in breast cancer cells can digest extracellular matrix in large acidic vesicles.

1990 • 116 citations

Stromelysin in tumor progression and metastasis

1990 • 105 citations

The role of interstitial collagens in cleft formation of mouse embryonic submandibular gland during initial branching

1988 • 101 citations

Transforming growth factor‐β1 stimulates macrophage urokinase expression and release of matrix‐bound basic fibroblast growth factor

1993 • 97 citations

Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice.

1995 • 88 citations

Urokinase binding and receptor identification in cultured endothelial cells.

1991 • 56 citations

Proteinases and proteinase inhibitors as modulators of animal cell growth

1992 • 14 citations