A Novel Function for the nm23-H1 Gene: Overexpression in Human Breast Carcinoma Cells Leads to the Formation of Basement Membrane and Growth Arrest

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

1992 • 1,047 citations

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane

1989 • 700 citations

Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity.

1991 • 659 citations

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm3-transfected melanoma cells

1991 • 548 citations

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development

1989 • 487 citations

Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential.

1989 • 398 citations

Identification of a second human nm23 gene, nm23-H2.

1991 • 357 citations

Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.

1993 • 298 citations

Expression of the Antimetastatic Gene nm23 in Human Breast Cancer: An Association WIth Good Prognosis

1991 • 298 citations

A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential.

1993 • 214 citations

Inhibition of cell motility after nm23 transfection of human and murine tumor cells.

1993 • 203 citations

The influence of tissue microenvironment (stroma and extracellular matrix) on the development and function of mammary epithelium.

1993 • 183 citations

Low nm23 protein expression in infiltrating ductal breast carcinomas correlates with reduced patient survival.

1991 • 166 citations

Positive Relationship Between Expression of Anti-metastatic Factor (nm23 Gene Product or Nucleoside Diphosphate Kinase) and Good Prognosis in Human Breast Cancer

1991 • 132 citations

Reduced expression of nm23‐H1, but not of nm23‐H2, is concordant with the frequency of lymph‐node metastasis of human breast cancer

1993 • 125 citations

Nm23 Protein Expression in Ductal In Situ and Invasive Human Breast Carcinoma

1993 • 119 citations

Embryonic expression of nm23 during mouse organogenesis.

1992 • 97 citations