Indirect recognition of donor HLA-DR peptides in organ allograft rejection.

Heart-Lung Transplantation

2016 • 2,165 citations

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1990 • 906 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice.

1978 • 791 citations

T Cell-Dependent B Cell Activation

1993 • 727 citations

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.

1994 • 539 citations

Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis.

1995 • 522 citations

Why do so many lymphocytes respond to major histocompatibility antigens?

1977 • 462 citations

An essential role for HLA–DM in antigen presentation by class II major histocompatibility molecules

1994 • 378 citations

The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice.

1993 • 325 citations

The molecular basis of alloreactivity

1990 • 278 citations

Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection.

1992 • 266 citations

HLA-DMA and DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

1994 • 247 citations

Contribution of direct and indirect recognition pathways to T cell alloreactivity.

1993 • 242 citations

Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific Th1 clones.

1988 • 241 citations

Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo.

1994 • 227 citations

Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides.

1992 • 218 citations

Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat.

1992 • 163 citations

SOLUBLE HLA ANTIGENS, ANTI-HLA ANTIBODIES, AND ANTIIDIOTYPIC ANTIBODIES IN THE CIRCULATION OF RENAL TRANSPLANT RECIPIENTS

1991 • 162 citations

Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells.

1989 • 156 citations

Role of Indirect Allorecognition in Allograft Rejection

1996 • 147 citations

Early signaling defects in human T cells anergized by T cell presentation of autoantigen.

1992 • 143 citations

Bmdp Statistical Software Manual: To Accompany the 1988 Software Release

1988 • 124 citations

The rat mixed lymphocyte reaction: roles of a dendritic cell in intestinal lymph and T-cell subsets defined by monoclonal antibodies.

1981 • 123 citations

T cell recognition of allo-peptides in context of syngeneic MHC

1991 • 98 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 94 citations

MEDIATION OF ACUTE BUT NOT CHRONIC REJECTION OF MHC-INCOMPATIBLE RAT KIDNEY GRAFTS BY ALLOREACTIVE CD4 T CELLS ACTIVATED BY THE DIRECT PATHWAY OF SENSITIZATION

1993 • 89 citations

Heterogeneity in antigen processing by different types of antigen-presenting cells. Effect of cell culture on antigen processing ability.

1992 • 85 citations

Limited T cell response to donor MHC peptides during allograft rejection. Implications for selective immune therapy in transplantation.

1994 • 85 citations

T cell recognition of allopeptides in context of syngeneic MHC.

1992 • 78 citations

THE INDIRECT PATHWAY OF ALLORECOGNITION

1995 • 74 citations

Allorecognition of isolated, denatured chains of class I and class II major histocompatibility complex molecules. Evidence for an important role for indirect allorecognition in transplantation

1992 • 66 citations

Limited usage of T cell receptor V beta genes by allopeptide-specific T cells.

1993 • 63 citations

Indirect T cell allorecognition: a cyclosporin A resistant pathway for T cell help for antibody production to donor MHC antigens

1993 • 57 citations

NOMENCLATURE FOR FACTORS OF THE HLA SYSTEM, 1994

1994 • 56 citations

Indirect Recognition of Donor MHC Class II Antigens in Human Transplantation

1996 • 53 citations

Indirect T Cell Recognition in Allograft Rejection

1996 • 46 citations

T Cell\-Dependent B Cell Activation

1993 • 45 citations

Molecular mimicry by major histocompatibility complex molecules and peptides accounts for some alloresponses

1992 • 42 citations

The Contribution of Peptides to T Cell Allorecognition and Allograft Rejection

1996 • 41 citations

T cell recognition of self-human histocompatibility leukocyte antigens (HLA)-DR peptides in context of syngeneic HLA-DR molecules.

1992 • 41 citations

New Approaches to Specific Immunomodulation in Transplantation

1996 • 29 citations

NOMENCLATURE FOR FACTORS OF THE HLA SYSTEM, 1995

1995 • 28 citations

Suppression of the Indirect Pathway of T Cell Reactivity by High Doses of Allopeptide

1995 • 22 citations

Antigen‐processing organelles from DRB1*1101 and DRB1*1104 B cell lines display a differential degradation activity

1995 • 16 citations

Presentation of a self-peptide for in vivo tolerance induction of CD4+ T cells is governed by a processing factor that maps to the class II region of the major histocompatibility complex locus.

1995 • 16 citations

T cell recognition of allo-peptides in context of syngeneic MHC

1991 • 15 citations

Additive value of immunologic monitoring to histologic grading of heart allograft biopsy specimens: implications for therapy.

1995 • 14 citations

Pathology of human cardiac transplantation.

1995 • 12 citations

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

1994 • 11 citations

The molecular basis of alloreactivity

1997 • 7 citations

Indirect recognition of donor MHC class II antigens in human transplantation

1997 • 2 citations