HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Map of the human MHC

1993 • 585 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

1992 • 380 citations

A role for peptide in determining MHC class II structure

1991 • 275 citations

Histocompatibility Testing 1984

1984 • 252 citations

A new human HLA class II-related locus, DM

1991 • 251 citations

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

1990 • 236 citations

Invariant Chain Peptides in Most HLA-DR Molecules of an Antigen-Processing Mutant

1992 • 218 citations

Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains

1982 • 183 citations

Epstein-Barr virus shuttle vector for stable episomal replication of cDNA expression libraries in human cells.

1988 • 154 citations

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation.

1992 • 125 citations

A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex.

1991 • 106 citations

A mouse monoclonal antibody detecting a DR-related MT2-like specificity: Serology and biochemistry

1984 • 97 citations

A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides.

1994 • 91 citations

Activation of human B cells. Comparison of the signal transduced by IL-4 to four different competence signals.

1989 • 90 citations

Direct demonstration of an HLA-DR allotypic determinant on the low molecular weight (beta) subunit using a mouse monoclonal antibody specific for DR3

1982 • 83 citations

MHC class II deletion mutant expresses normal levels of transgene encoded class II molecules that have abnormal conformation and impaired antigen presentation ability.

1992 • 72 citations

Gene dosage and gene expression in the HLA region: Evidence from deletion variants

1982 • 66 citations

HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants.

1985 • 60 citations

<scp>l</scp>-Histidinol Provides Effective Selection of Retrovirus-Vector-Transduced Keratinocytes Without Impairing Their Proliferative Potential

1991 • 47 citations

Induction of HLA mutations by chemical mutagens in human lymphoid cells

1977 • 44 citations

Transcriptional regulation of HLA class II and invariant chain genes.

1985 • 42 citations

Deletion mapping of HLA and chromosome 6p genes.

1985 • 35 citations

Characterization of a monoclonal antibody recognizing a polymorphic epitope mainly on HLA‐DPw2 and DPw4 molecules

1989 • 13 citations

Recognition by a murine monoclonal antibody of a unique epitope specific for the human alloantigen HLA-B8

1984 • 7 citations