Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

Excitotoxic cell death

1992 • 2,307 citations

Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

1990 • 689 citations

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2

1993 • 424 citations

Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells

1989 • 375 citations

Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux

1993 • 331 citations

Volume regulation in astrocytes: A role for taurine as an osmoeffector

1988 • 260 citations

Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels.

1995 • 191 citations

High Sensitivity of Glutamate Uptake to Extracellular Free Arachidonic Acid Levels in Rat Cortical Synaptosomes and Astrocytes

1992 • 188 citations

Does taurine act as an osmoregulatory substance in the rat brain?

1988 • 187 citations

Volume‐regulatory Cl‐ channel currents in cultured human epithelial cells.

1992 • 185 citations

Swelling-activated Organic Osmolyte Channels

1997 • 155 citations

Swelling-activated organic osmolyte efflux: A new role for anion channels

1995 • 153 citations

Sequential Development of Reversible and Irreversible Neuronal Damage Following Cerebral Ischemia

1984 • 128 citations

Potassium and Taurine Release Are Highly Correlated with Regulatory Volume Decrease in Neonatal Primary Rat Astrocyte Cultures

1994 • 126 citations

Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortex

1997 • 105 citations

Contribution of organic and inorganic osmolytes to volume regulation in rat brain cells in culture

1993 • 103 citations

Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex

1996 • 100 citations

Volume regulation in brain cells: Cellular and molecular mechanisms

1996 • 98 citations

Complete cerebral ischemia

1979 • 97 citations

Mechanism and regulation of swelling-activated inositol efflux in brain glial cells

1993 • 95 citations

Regulation of taurine transport in Ehrlich ascites tumor cells

1993 • 94 citations

A possible role for phospholipases in the release of neurotransmitter amino acids from ischemic rat cerebral cortex

1995 • 85 citations

Amino acids as volume-regulatory osmolytes in mammalian cells

1991 • 82 citations

Swelling-Induced Arachidonic Acid Release via the 85-kDa cPLA₂in Human Neuroblastoma Cells

1998 • 79 citations

Amino acid current through anion channels in cultured human glial cells

1995 • 78 citations

Cell Swelling Activates Phospholipase A 2 in Ehrlich Ascites Tumor Cells

1997 • 77 citations

Tamoxifen, a chloride channel blocker, reduces glutamate and aspartate release from the ischemic cerebral cortex

1998 • 77 citations

Role of Calmodulin and Protein Kinase C in Astrocytic Cell Volume Regulation

1992 • 69 citations

Cell volume regulation in cultured cerebellar granule neurons

1993 • 68 citations

Effects of anion channel blockers on hyposmotically induced amino acid release from the in vivo rat cerebral cortex.

1999 • 62 citations

Role of Phosphoinositide Hydrolysis in Astrocyte Volume Regulation

1993 • 62 citations

Hepoxilin A3 is the endogenous lipid mediator opposing hypotonic swelling of intact human platelets.

1993 • 58 citations

Glial Swelling in Ischemia: A Hypothesis

1993 • 55 citations

Cl channel blockers inhibit the volume-activated efflux of Cl and taurine in cultured neurons

1996 • 52 citations

Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl⁻currents

1999 • 48 citations

Inhibition by polyunsaturated fatty acids of cell volume regulation and osmolyte fluxes in astrocytes

1995 • 46 citations

Role of eicosanoids, inositol phosphates and extracellular Ca²⁺ in cell‐volume regulation of rat liver

1991 • 41 citations

Protein Kinases, Phosphatases, and the Control of Cell Volume

1992 • 39 citations

Involvement of PKC‐α in regulatory volume decrease responses and activation of volume‐sensitive chloride channels in human cervical cancer HT‐3 cells

1998 • 37 citations

Swelling-activated amino acid efflux in the human neuroblastoma cell line CHP-100

1996 • 36 citations

DIFFERENCES BETWEEN ASTROCYTES IN PRIMARY CULTURES AND GLIAL CELL LINES IN UPTAKE AND METABOLISM OF PUTATIVE AMINO ACID TRANSMITTERS

1977 • 30 citations

Accumulation of glutamate is regulated by calcium and protein kinase C in rat hippocampal slices exposed to ischemic states

1993 • 22 citations

Amino acid release during volume regulation by cardiac cells: Cellular mechanisms

1998 • 17 citations