Identification of the Calmodulin-binding Domain of Recombinant Calcium-independent Phospholipase A2β

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex

1992 • 1,031 citations

Sequence motifs for calmodulin recognition

1997 • 871 citations

How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

1990 • 839 citations

Molecular and Structural Basis of Target Recognition by Calmodulin

1995 • 752 citations

Modulation of Calmodulin Plasticity in Molecular Recognition on the Basis of X-Ray Structures

1993 • 615 citations

Calcium-mediated Translocation of Cytosolic Phospholipase A2 to the Nuclear Envelope and Endoplasmic Reticulum

1995 • 469 citations

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF

1995 • 424 citations

Calmodulin-binding domains: just two faced or multi-faceted?

1995 • 368 citations

Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.

1994 • 352 citations

Functional Coupling Between Various Phospholipase A2s and Cyclooxygenases in Immediate and Delayed Prostanoid Biosynthetic Pathways

1999 • 350 citations

Translocation of the 85-kDa Phospholipase A2 from Cytosol to the Nuclear Envelope in Rat Basophilic Leukemia Cells Stimulated with Calcium Ionophore or IgE/Antigen

1995 • 331 citations

Identification of neutral active phospholipase C which hydrolyzes choline glycerophospholipids and plasmalogen selective phospholipase A2 in canine myocardium.

1985 • 315 citations

A Novel Cytosolic Calcium-independent Phospholipase A2 Contains Eight Ankyrin Motifs

1997 • 302 citations

The central helix of calmodulin functions as a flexible tether.

1988 • 245 citations

Characterization of the lipid acyl hydrolase activity of the major potato (Solanum tuberosum) tuber protein, patatin, by cloning and abundant expression in a baculovirus vector

1988 • 243 citations

An Autoinhibitory Control Element Defines Calcium-regulated Isoforms of Nitric Oxide Synthase

1997 • 237 citations

Purification and characterization of canine myocardial cytosolic phospholipase A2. A calcium-independent phospholipase with absolute f1-2 regiospecificity for diradyl glycerophospholipids.

1990 • 234 citations

The Genomic Organization, Complete mRNA Sequence, Cloning, and Expression of a Novel Human Intracellular Membrane-associated Calcium-independent Phospholipase A2

2000 • 214 citations

Evidence for a bidomain structure of constitutive cerebellar nitric oxide synthase.

1994 • 201 citations

Functional domain structure of calcineurin A: mapping by limited proteolysis

1989 • 201 citations

The calmodulin binding domain of nitric oxide synthase and adenylyl cyclase

1993 • 165 citations

A fluorescent calmodulin that reports the binding of hydrophobic inhibitory ligands

1983 • 129 citations

Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet .beta.-cells

1993 • 123 citations

Depletion of Intracellular Calcium Stores Activates Smooth Muscle Cell Calcium-independent Phospholipase A2

1997 • 122 citations

Characterization of the calmodulin-binding and catalytic domains in skeletal muscle myosin light chain kinase.

1985 • 108 citations

Ca2+-dependent interaction of 5-dimethylaminonaphthalene-1-sulfonyl-calmodulin with cyclic nucleotide phosphodiesterase, calcineurin, and troponin I.

1982 • 107 citations

Molecular mechanisms of calmodulin's functional versatility

1998 • 106 citations

Target sequence recognition by the calmodulin superfamily: implications from light chain binding to the regulatory domain of scallop myosin.

1995 • 106 citations

Arachidonic acid release from aortic smooth muscle cells induced by [Arg8]vasopressin is largely mediated by calcium-independent phospholipase A2.

1993 • 105 citations

Molecular mechanisms of calmodulin's functional versatility

1998 • 98 citations

Involvement of Group VI Ca2+-independent Phospholipase A2 in Protein Kinase C-dependent Arachidonic Acid Liberation in Zymosan-stimulated Macrophage-like P388D1 Cells

1999 • 96 citations

Long‐term potentiation requires activation of calcium‐independent phospholipase A₂

1995 • 94 citations

Expression, Purification, and Kinetic Characterization of a Recombinant 80-kDa Intracellular Calcium-independent Phospholipase A2

1996 • 93 citations

The Calcium-dependent Association and Functional Coupling of Calmodulin with Myocardial Phospholipase A2

1996 • 89 citations

Characterization of an ATP-stimulatable calcium2+ independent phospholipase A2 from clonal insulin-secreting HIT cells and rat pancreatic islets: a possible molecular component of the .beta.-cell fuel sensor

1994 • 65 citations

Mass Spectrometric Evidence That Agents That Cause Loss of Ca2+ from Intracellular Compartments Induce Hydrolysis of Arachidonic Acid from Pancreatic Islet Membrane Phospholipids by a Mechanism That Does Not Require a Rise in Cytosolic Ca2+ Concentration**This work was supported by U.S. Public Health Service grants PO1-HL57278, P41-RR-00954, and S10-RR-11260 and by an American Diabetes Association Career Development Award (S.R.).

1998 • 61 citations

Nitric Oxide Activates the Glucose-dependent Mobilization of Arachidonic Acid in a Macrophage-like Cell Line (RAW 264.7) That Is Largely Mediated by Calcium-independent Phospholipase A2

1995 • 53 citations

Ca²⁺ Regulates Calmodulin Binding to IQ Motifs in IRS-1

1996 • 50 citations

The N-terminal Moiety of CDC25Mm, a GDP/GTP Exchange Factor of Ras Proteins, Controls the Activity of the Catalytic Domain

1997 • 44 citations

Thrombin activates a membrane-associated calcium-independent PLA₂ in ventricular myocytes

1998 • 43 citations

The Calmodulin‐binding Domain of the Inducible (Macrophage) Nitric Oxide Synthase

1995 • 42 citations

Identification of the domains of neuronal nitric oxide synthase by limited proteolysis

1996 • 36 citations

Multiple phospholipase A2 activities in canine vascular smooth muscle

1992 • 31 citations