Back to search

Possible antidepressant effects and mechanisms of memantine in behaviors and synaptic plasticity of a depression rat model

Data up to Jan 2025

Published2011
Citations82
References57

Total Citations Per Year

Abstract

References (57)

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States

1994 • 12,456 citations

Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

2003 • 8,039 citations

Place navigation impaired in rats with hippocampal lesions

1982 • 6,277 citations

LTP and LTD

2004 • 3,754 citations

Antidepressant effects of ketamine in depressed patients

2000 • 3,482 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Neurobiology of Depression

2002 • 3,057 citations

Subgenual prefrontal cortex abnormalities in mood disorders

1997 • 2,646 citations

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

2010 • 2,611 citations

Causal Relationship Between Stressful Life Events and the Onset of Major Depression

1999 • 2,365 citations

Memantine in Moderate-to-Severe Alzheimer's Disease

2003 • 1,889 citations

Animal models of neuropsychiatric disorders

2010 • 1,812 citations

Emotion, Cognition, and Behavior

2002 • 1,799 citations

Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation

1997 • 1,773 citations

Chronic Mild Stress (CMS) Revisited: Consistency and Behavioural-Neurobiological Concordance in the Effects of CMS

2005 • 1,515 citations

Memantine Treatment in Patients With Moderate to Severe Alzheimer Disease Already Receiving Donepezil

2004 • 1,350 citations

The cellular neurobiology of depression

2001 • 1,169 citations

Cognitive deficits in depression: Possible implications for functional neuropathology

2001 • 1,146 citations

Chronic mild stress-induced anhedonia: A realistic animal model of depression

1992 • 1,120 citations

Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting

2006 • 895 citations

Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data

1999 • 841 citations

Depression: a case of neuronal life and death?

2004 • 609 citations

Differentiating anxiety and depression: A test of the cognitive content-specificity hypothesis.

1987 • 547 citations

Glutamate as a therapeutic target in psychiatric disorders

2004 • 525 citations

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

1998 • 487 citations

Differentiating anxiety and depression: A test of the cognitive content-specificity hypothesis.

1987 • 485 citations

Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression

2008 • 386 citations

Glutamate-based antidepressants: 20 years on

2009 • 376 citations

Chronic Unpredictable Stress Induces a Cognitive Deficit and Anxiety-Like Behavior in Rats that is Prevented by Chronic Antidepressant Drug Treatment

2007 • 370 citations

A Double-Blind, Placebo-Controlled Study of Memantine in the Treatment of Major Depression

2006 • 365 citations

Downregulation of Endocannabinoid Signaling in the Hippocampus Following Chronic Unpredictable Stress

2004 • 346 citations

Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.

1997 • 266 citations

Motoneuron-Specific Expression of NR3B, a Novel NMDA-Type Glutamate Receptor Subunit That Works in a Dominant-Negative Manner

2001 • 255 citations

Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.

1997 • 253 citations

Contribution of Hippocampal and Extra-Hippocampal NR2B-Containing NMDA Receptors to Performance on Spatial Learning Tasks

2008 • 237 citations

Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats

2009 • 233 citations

Reinforcement and Reversal Learning in First-Episode Psychosis

2008 • 155 citations

Chapter 28 The glutamate synapse in neuropsychiatric disorders: Focus on schizophrenia and Alzheimer's disease

1998 • 148 citations

Memantine reduces oxidative damage and enhances long-term recognition memory in aged rats

2007 • 139 citations

Enhanced NMDA Receptor-Mediated Synaptic Transmission, Enhanced Long-Term Potentiation, and Impaired Learning and Memory in Mice Lacking IRSp53

2009 • 136 citations

Low Doses of Memantine Disrupt Memory in Adult Rats

2006 • 129 citations

Role of the anterodorsal and anteroventral nuclei of the thalamus in spatial memory in the rat

2002 • 125 citations

Enhancement of long-term spatial memory in adult rats by the noncompetitive NMDA receptor antagonists, memantine and neramexane

2006 • 124 citations

Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B glutamate receptor subunits in rat forebrain

2006 • 116 citations

Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression?

2009 • 111 citations

Post weaning social isolation influences spatial cognition, prefrontal cortical synaptic plasticity and hippocampal potassium ion channels in Wistar rats

2010 • 110 citations

The Hippocampus and Spatial Memory: Findings with a Novel Modification of the Water Maze

2007 • 108 citations

Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine

2009 • 74 citations

CPT performance in major depressive disorder before and after treatment with imipramine or fluvoxamine

2002 • 72 citations

Topographic relationship between anteromedial thalamic nucleus neurons and their cortical terminal fields in the rat

1993 • 48 citations

Spatial Working and Reference Memory in Rats Bred for Autonomic Sensitivity to Cholinergic Stimulation: Acquisition, Accuracy, Speed, and Effects of Cholinergic Drugs

1995 • 41 citations

Memantine, but not dizocilpine, ameliorates cognitive deficits in adult rats withdrawn from chronic ingestion of alcohol

2001 • 35 citations

Therapeutically relevant plasma concentrations of memantine produce significant L-N-methyl-D-aspartate receptor occupation and do not impair learning in rats

2008 • 34 citations

Medial prefrontal administration of MK-801 impairs T-maze discrimination reversal learning in weanling rats

2009 • 28 citations

Directionality index of neural information flow as a measure of synaptic plasticity in chronic unpredictable stress rats

2010 • 20 citations

Cited By (0)

Loading...
Possible antidepressant effects and mechanisms of memantine in behaviors and synaptic… (2011) – Neuroscience | Metascience Observatory Explorer