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Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B glutamate receptor subunits in rat forebrain

Data up to Jan 2025

Published2006
Citations116
References72

Total Citations Per Year

Abstract

References (72)

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol

1964 • 5,892 citations

Long-Term Potentiation and Memory

2004 • 1,888 citations

Genetic enhancement of learning and memory in mice

1999 • 1,831 citations

Rapid separation of lipid classes in high yield and purity using bonded phase columns.

1985 • 939 citations

Dentritic spines : structure, dynamics and regulation

2001 • 915 citations

Mechanisms of action of docosahexaenoic acid in the nervous system

2001 • 909 citations

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase.

1991 • 660 citations

The Biochemistry of n-3 Polyunsaturated Fatty Acids

2002 • 628 citations

Distribution and fatty acid composition of phosphoglycerides in normal human brain

1968 • 623 citations

Nerve Growth Factor Treatment Increases Brain-Derived Neurotrophic Factor Selectively in TrkA-Expressing Dorsal Root Ganglion Cells and in Their Central Terminations within the Spinal Cord

1997 • 500 citations

Regional membrane phospholipid alterations in Alzheimer's disease.

1998 • 422 citations

Life-span dendritic and spine changes in areas 10 and 18 of human cortex: A quantitative golgi study

1997 • 388 citations

Cognitive decline and fatty acid composition of erythrocyte membranes—The EVA Study

2003 • 349 citations

Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2

2003 • 302 citations

Integration of biochemical signalling in spines

2005 • 283 citations

The relationship between age and the fatty acid composition of cerebral cortex and erythrocytes in human subjects

2001 • 269 citations

Evolutionary aspects of omega-3 fatty acids in the food supply

1999 • 255 citations

The Molecular Basis of Memantine Action in Alzheimers Disease and Other Neurologic Disorders: Low-affinity, Uncompetitive Antagonism

2005 • 249 citations

The AMPAR subunit GluR2: still front and center-stage11Published on the World Wide Web on 30 October 2000.

2000 • 244 citations

Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases

2003 • 240 citations

Dietary n‐3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease

2005 • 239 citations

Age-related changes in synaptic function: analysis of the effect of dietary supplementation with ω-3 fatty acids

1999 • 220 citations

Dendritic Spine Geometry: Functional Implication and Regulation

2005 • 219 citations

Chronic Administration Of Docosahexaenoic Acid Improves The Performance Of Radial Arm Maze Task In Aged Rats

2001 • 204 citations

Specific phospholipid fatty acid composition of brain regions in mice: effects of n–3 polyunsaturated fatty acid deficiency and phospholipid supplementation

2000 • 193 citations

Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified alpha-linolenic and linoleic acids: determination of the optimal omega 3-to-omega 6 ratio.

1993 • 166 citations

Facilitatory effect of docosahexaenoic acid on N‐methyl‐D‐aspartate response in pyramidal neurones of rat cerebral cortex.

1994 • 153 citations

Mild cognitive impairment (MCI) represents early-stage Alzheimer's disease

2005 • 152 citations

Dietary Supplementation with Vitamin E Reverses the Age-related Deficit in Long Term Potentiation in Dentate Gyrus

1998 • 149 citations

Calcium Dysregulation in the Aging Brain

2002 • 140 citations

Age and insulin-like growth factor-1 modulate N-methyl-D-aspartate receptor subtype expression in rats

2000 • 138 citations

Essential Fatty Acids Preparation (Sr-3) Improves Alzheimer's Patients Quality of Life

1996 • 137 citations

Aging and sex influence the anatomy of the rat anterior cingulate cortex

2002 • 132 citations

Age-related changes in phospholipid fatty acid composition and monoaminergic neurotransmission in the hippocampus of rats fed a balanced or an n-3 polyunsaturated fatty acid-deficient diet

1997 • 127 citations

The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed

1997 • 124 citations

Δ6 desaturase in brain and liver during development and aging

1990 • 121 citations

Potential role of dietary ω-3 essential fatty acids on some oxidant/antioxidant parameters in rats’ corpus striatum

2003 • 112 citations

Aging of glutamate receptors: correlations between binding and spatial memory performance in mice

1998 • 110 citations

Age-associated changes in central nervous system glycerolipid composition and metabolism.

2002 • 107 citations

Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat

2000 • 107 citations

Differential expression of N‐methyl‐<scp>d</scp>‐aspartate receptor NR2 isoforms in Alzheimer's disease

2004 • 106 citations

DHA-enriched phospholipid diets modulate age-related alterations in rat hippocampus

2002 • 103 citations

Effect of Docosahexaenoic Acid on the Synthesis of Phosphatidylserine in Rat Brain Microsomes and C6 Glioma Cells

1998 • 99 citations

Morphological alterations in neurons forming corticocortical projections in the neocortex of aged Patas monkeys

2002 • 96 citations

Deficits in the expression of the NR2B subunit in the hippocampus of aged Fisher 344 rats

2001 • 95 citations

The potent free radical scavenger α-lipoic acid improves memory in aged mice: Putative relationship to NMDA receptor deficits

1993 • 89 citations

Sulindac improves memory and increases NMDA receptor subunits in aged Fischer 344 rats

2003 • 89 citations

Age-related changes in GluR2 and NMDAR1 glutamate receptor subunit protein immunoreactivity in corticocortically projecting neurons in macaque and patas monkeys

2002 • 83 citations

High-Performance Liquid Chromatographic Analysis of Phospholipids from Different Sources with Combined Fluorescence and Ultraviolet Detection

1994 • 82 citations

Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats

2001 • 82 citations

Age-related changes in LTP and antioxidant defenses are reversed by an α-lipoic acid-enriched diet

1999 • 81 citations

Age-related changes in prefrontal cortex of Macaca mulatta: Synaptic density

1980 • 78 citations

Age-related changes in expression of ampa-selective glutamate receptor subunits: Is calcium-permeability altered in hippocampal neurons?

1994 • 69 citations

A single amino acid residue determines the Ca2+ permeability of AMPA-selective glutamate receptor channels

1991 • 68 citations

Age-related alterations of NMDA-receptor properties in the mouse forebrain: partial restoration by chronic phosphatidylserune treatment

1992 • 66 citations

Ionotropic glutamate receptor subtypes in the aged memory-impaired and unimpaired Long–Evans rat

1996 • 66 citations

Long-term potentiation in aged rats is restored when the age-related decrease in polyunsaturated fatty acid concentration is reversed

2002 • 66 citations

The role of peroxisomes in aging

1998 • 64 citations

Changes in the expression of the NR2B subunit during aging in macaque monkeys

2003 • 56 citations

Age-dependent loss of NMDA receptors in hippocampus, striatum, and frontal cortex of the rat: Prevention by acetyl-l-carnitine

1994 • 52 citations

Microdetermination of phosphoinositides in a single extract

1985 • 46 citations

Decline in motor functions in aging is related to the loss of NMDA receptors

2001 • 36 citations

Visual recognition memory is related to basic expression level of NMDA receptor NR1/NR2B subtype in hippocampus and striatum of rats1

2005 • 16 citations

Experimental approaches and drugs in development for the treatment of dementia

2001 • 11 citations

EFFECTS OF DIETARY LONG CHAIN PUFAs ON HIPPOCAMPAL LIPID PEROXIDATION AND NMDA RECEPTOR SUBUNITS A AND B CONCENTRATION IN STREPTOZOTOCIN-DIABETIC RATS

2004 • 9 citations

Lipoprotein lipase activity and protein oxidative damage are increased in brain by age but not by fish oil ingestion

1998 • 4 citations

Sphingomyelin biosynthesis and efflux correlates with cholesterol metabolism and is higher in vascular endothelial cells than in smooth muscle cells

1993 • 2 citations

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Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related… (2006) – Neurobiology of Aging | Metascience Observatory Explorer