Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine
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References (46)
Inflammation and Alzheimer's disease
2000 • 4,315 citations
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 • 2,527 citations
Neural plasticity in the ageing brain
2005 • 1,441 citations
Hippocampal synaptic enhancement and information storage within a distributed memory system
1987 • 1,291 citations
Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
1995 • 1,181 citations
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes
1998 • 1,138 citations
Requirement for Hippocampal CA3 NMDA Receptors in Associative Memory Recall
2002 • 1,090 citations
In-vivo measurement of activated microglia in dementia
2001 • 1,025 citations
Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles
1999 • 1,024 citations
CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity
2001 • 1,024 citations
Inhibition of Activity-Dependent Arc Protein Expression in the Rat Hippocampus Impairs the Maintenance of Long-Term Potentiation and the Consolidation of Long-Term Memory
2000 • 1,007 citations
Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data
1999 • 841 citations
Arc/Arg3.1 Is Essential for the Consolidation of Synaptic Plasticity and Memories
2006 • 810 citations
Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases.
2003 • 788 citations
Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases
2003 • 761 citations
Distinct Ensemble Codes in Hippocampal Areas CA3 and CA1
2004 • 760 citations
Neuronal ‘On’ and ‘Off’ signals control microglia
2007 • 736 citations
Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network
1992 • 700 citations
Differences in Hippocampal Neuronal Population Responses to Modifications of an Environmental Context: Evidence for Distinct, Yet Complementary, Functions of CA3 and CA1 Ensembles
2004 • 455 citations
The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence
2003 • 382 citations
Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge
1989 • 374 citations
Impaired Spatial Representation in CA1 after Lesion of Direct Input from Entorhinal Cortex
2008 • 360 citations
Spatial Exploration-InducedArcmRNA and Protein Expression: Evidence for Selective, Network-Specific Reactivation
2005 • 358 citations
Multistability of cognitive maps in the hippocampus of old rats
1997 • 355 citations
Ensemble Dynamics of Hippocampal Regions CA3 and CA1
2004 • 340 citations
The importance of inflammatory mechanisms in alzheimer disease
1998 • 325 citations
ROLE OF CEREBRAL INFLAMMATION AFTER TRAUMATIC BRAIN INJURY: A REVISITED CONCEPT
2001 • 324 citations
Tumor Necrosis Factor α Inhibits Glutamate Uptake by Primary Human Astrocytes
1996 • 317 citations
The Role of the Hippocampus in Solving the Morris Water Maze
1998 • 298 citations
Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
2001 • 250 citations
A Double Dissociation between Hippocampal Subfields
2004 • 240 citations
A hebbian form of long-term potentiation dependent on mGluR1a in hippocampal inhibitory interneurons
2001 • 198 citations
Memory for Spatial Location: Role of the Hippocampus in Mediating Spatial Pattern Separation
1998 • 190 citations
Recent behavioral history modifies coupling between cell activity and Arc gene transcription in hippocampal CA1 neurons
2006 • 182 citations
Neuronal Chemokines: Versatile Messengers In Central Nervous System Cell Interaction
2007 • 170 citations
NMDA Receptor Blockade with Memantine Attenuates White Matter Injury in a Rat Model of Periventricular Leukomalacia
2008 • 169 citations
Brain Aging: Changes in the Nature of Information Coding by the Hippocampus
1997 • 162 citations
Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat
2006 • 152 citations
Vesicle-Mediated Transport and Release of CCL21 in Endangered Neurons: A Possible Explanation for Microglia Activation Remote from a Primary Lesion
2005 • 134 citations
Neuroinflammation Alters the Hippocampal Pattern of Behaviorally InducedArcExpression
2005 • 126 citations
Brain Aging: Impaired Coding of Novel Environmental Cues
1997 • 124 citations
Macrophage/Microglial Accumulation and Proliferating Cell Nuclear Antigen Expression in the Central Nervous System in Human Immunodeficiency Virus Encephalopathy
2004 • 117 citations
Neuron-microglia signaling: Chemokines as versatile messengers
2008 • 101 citations
Inhibition of Glutamate Uptake with <scp>l</scp>‐trans‐Pyrrolidine‐2,4‐Dicarboxylate Potentiates Glutamate Toxicity in Primary Hippocampal Cultures
1993 • 100 citations
Bidirectional Hebbian Plasticity at Hippocampal Mossy Fiber Synapses on CA3 Interneurons
2008 • 65 citations
Reconciling Barnes et al. (1997) and Tanila et al. (1997a,b)
1998 • 21 citations